Literature DB >> 24734311

Chocolate--guilty pleasure or healthy supplement?

Laura S Latham, Zeb K Hensen, Deborah S Minor.   

Abstract

Dark chocolate and other cocoa products are popular in the population as a whole, but their overall health benefit remains controversial. Observations from the Kuna Indian population have shown an impressive cardiovascular health benefit from cocoa. For various reasons, this benefit has not been as robust as in other populations. Additionally, several mechanisms have been proposed that might confer cocoa's possible health benefit, but no consensus has been reached on cocoa's physiologic role in promoting cardiovascular health. Flavanols, as well as theobromine, may contribute to enhancements in endothelial function and subsequent improvements in various contributors to cardiovascular disease (CVD) including hypertension, platelet aggregation and adhesion, insulin resistance, and hypercholesterolemia. While the benefits of cocoa may be altered at the various stages of growth, development, and production, it appears that for many people "healthy" dark chocolate may, indeed, provide a pleasurable role in CVD risk reduction. The objectives of this review are to discuss the associations of cocoa with decreased blood pressure and improved CVD risk, to describe the possible mechanisms for these potential benefits, and to highlight considerations for the use of cocoa as a dietary supplement.

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Year:  2014        PMID: 24734311      PMCID: PMC8031600          DOI: 10.1111/jch.12223

Source DB:  PubMed          Journal:  J Clin Hypertens (Greenwich)        ISSN: 1524-6175            Impact factor:   3.738


  36 in total

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Journal:  J Agric Food Chem       Date:  2006-01-11       Impact factor: 5.279

2.  Effects of diet and sodium intake on blood pressure: subgroup analysis of the DASH-sodium trial.

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Journal:  Ann Intern Med       Date:  2001-12-18       Impact factor: 25.391

Review 3.  Blood pressure and cardiovascular risk: what about cocoa and chocolate?

Authors:  Davide Grassi; Giovambattista Desideri; Claudio Ferri
Journal:  Arch Biochem Biophys       Date:  2010-06-01       Impact factor: 4.013

4.  Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.

Authors:  Aram V Chobanian; George L Bakris; Henry R Black; William C Cushman; Lee A Green; Joseph L Izzo; Daniel W Jones; Barry J Materson; Suzanne Oparil; Jackson T Wright; Edward J Roccella
Journal:  Hypertension       Date:  2003-12-01       Impact factor: 10.190

5.  Effect of cocoa and theobromine consumption on serum HDL-cholesterol concentrations: a randomized controlled trial.

Authors:  Nicole Neufingerl; Yvonne E M P Zebregs; Ewoud A H Schuring; Elke A Trautwein
Journal:  Am J Clin Nutr       Date:  2013-04-17       Impact factor: 7.045

6.  Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans.

Authors:  Jaakko Mursu; Sari Voutilainen; Tarja Nurmi; Tiina H Rissanen; Jyrki K Virtanen; Jari Kaikkonen; Kristiina Nyyssönen; Jukka T Salonen
Journal:  Free Radic Biol Med       Date:  2004-11-01       Impact factor: 7.376

7.  Plasma LDL and HDL cholesterol and oxidized LDL concentrations are altered in normo- and hypercholesterolemic humans after intake of different levels of cocoa powder.

Authors:  Seigo Baba; Midori Natsume; Akiko Yasuda; Yuko Nakamura; Takaaki Tamura; Naomi Osakabe; Minoru Kanegae; Kazuo Kondo
Journal:  J Nutr       Date:  2007-06       Impact factor: 4.798

8.  Cocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertension.

Authors:  Ranganath Muniyappa; Gail Hall; Terrie L Kolodziej; Rajaram J Karne; Sonja K Crandon; Michael J Quon
Journal:  Am J Clin Nutr       Date:  2008-12       Impact factor: 7.045

9.  Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women.

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Journal:  Am J Clin Nutr       Date:  2007-03       Impact factor: 7.045

Review 10.  Flavanols and platelet reactivity.

Authors:  Debra A Pearson; Roberta R Holt; Dietrich Rein; Teresa Paglieroni; Harold H Schmitz; Carl L Keen
Journal:  Clin Dev Immunol       Date:  2005-03
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  11 in total

Review 1.  What an anticardiovascular diet should be in 2015.

Authors:  David R Jacobs; Linda C Tapsell
Journal:  Curr Opin Lipidol       Date:  2015-08       Impact factor: 4.776

2.  Chocolate is good for me, right?

Authors:  F Willford Germino
Journal:  J Clin Hypertens (Greenwich)       Date:  2013-12-13       Impact factor: 3.738

Review 3.  Dietary phytochemicals and neuro-inflammaging: from mechanistic insights to translational challenges.

Authors:  Sergio Davinelli; Michael Maes; Graziamaria Corbi; Armando Zarrelli; Donald Craig Willcox; Giovanni Scapagnini
Journal:  Immun Ageing       Date:  2016-04-14       Impact factor: 6.400

Review 4.  Habitual chocolate consumption and the risk of incident heart failure among healthy men and women.

Authors:  C S Kwok; Y K Loke; A A Welch; R N Luben; M A H Lentjes; S M Boekholdt; R Pfister; M A Mamas; N J Wareham; K-T Khaw; P K Myint
Journal:  Nutr Metab Cardiovasc Dis       Date:  2016-01-28       Impact factor: 4.222

5.  Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice.

Authors:  Yuta Nakagawa; Kana Ishimura; Satomi Oya; Masaki Kamino; Yasuyuki Fujii; Fumio Nanba; Toshiya Toda; Takeshi Ishii; Takahiro Adachi; Yoshitomo Suhara; Naomi Osakabe
Journal:  PLoS One       Date:  2018-07-30       Impact factor: 3.240

Review 6.  Dietary Polyphenols Targeting Arterial Stiffness: Interplay of Contributing Mechanisms and Gut Microbiome-Related Metabolism.

Authors:  Tess De Bruyne; Bieke Steenput; Lynn Roth; Guido R Y De Meyer; Claudia Nunes Dos Santos; Kateřina Valentová; Maija Dambrova; Nina Hermans
Journal:  Nutrients       Date:  2019-03-08       Impact factor: 5.717

7.  Elucidation of the Interaction between Flavan-3-ols and Bovine Serum Albumin and Its Effect on Their In-Vitro Cytotoxicity.

Authors:  Yasuyuki Fujii; Yoshitomo Suhara; Yusuke Sukikara; Tomohiro Teshima; Yoshihisa Hirota; Kenjiro Yoshimura; Naomi Osakabe
Journal:  Molecules       Date:  2019-10-11       Impact factor: 4.411

Review 8.  At the interface of antioxidant signalling and cellular function: Key polyphenol effects.

Authors:  Asimina Kerimi; Gary Williamson
Journal:  Mol Nutr Food Res       Date:  2016-03-29       Impact factor: 5.914

Review 9.  To Eat or Not to Eat: A Review of the Relationship between Chocolate and Migraines.

Authors:  Magdalena Nowaczewska; Michał Wiciński; Wojciech Kaźmierczak; Henryk Kaźmierczak
Journal:  Nutrients       Date:  2020-02-26       Impact factor: 5.717

Review 10.  Chocolate--guilty pleasure or healthy supplement?

Authors:  Laura S Latham; Zeb K Hensen; Deborah S Minor
Journal:  J Clin Hypertens (Greenwich)       Date:  2014-02       Impact factor: 3.738

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