Literature DB >> 22743708

Get on the exosome bus with ALIX.

James H Hurley1, Greg Odorizzi.   

Abstract

Exosomes have a growing inventory of functions, but the mechanism of protein sorting into exosomes has been unclear. Now, a signal sequence first described in viral budding provides just such a cargo sorting mechanism, revealing closer-than-expected parallelism between exosome biogenesis and the ESCRT-dependent endolysosomal pathway.

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Year:  2012        PMID： 22743708     DOI： 10.1038/ncb2530

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  15 in total

1.  Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.

Authors:  Maria Francesca Baietti; Zhe Zhang; Eva Mortier; Aurélie Melchior; Gisèle Degeest; Annelies Geeraerts; Ylva Ivarsson; Fabienne Depoortere; Christien Coomans; Elke Vermeiren; Pascale Zimmermann; Guido David
Journal:  Nat Cell Biol       Date:  2012-06-03       Impact factor: 28.824

Review 2.  The ESCRT complexes.

Authors:  James H Hurley
Journal:  Crit Rev Biochem Mol Biol       Date:  2010-07-23       Impact factor: 8.250

3.  An Alix fragment potently inhibits HIV-1 budding: characterization of binding to retroviral YPXL late domains.

Authors:  Utpal M Munshi; Jaewon Kim; Kunio Nagashima; James H Hurley; Eric O Freed
Journal:  J Biol Chem       Date:  2006-12-08       Impact factor: 5.157

Review 4.  Cell biology of the ESCRT machinery.

Authors:  Phyllis I Hanson; Soomin Shim; Samuel A Merrill
Journal:  Curr Opin Cell Biol       Date:  2009-06-26       Impact factor: 8.382

5.  The P4-ATPase TAT-5 inhibits the budding of extracellular vesicles in C. elegans embryos.

Authors:  Ann M Wehman; Corey Poggioli; Peter Schweinsberg; Barth D Grant; Jeremy Nance
Journal:  Curr Biol       Date:  2011-11-17       Impact factor: 10.834

6.  Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding.

Authors:  Robert D Fisher; Hyo-Young Chung; Qianting Zhai; Howard Robinson; Wesley I Sundquist; Christopher P Hill
Journal:  Cell       Date:  2007-03-09       Impact factor: 41.582

7.  ALIX catches HIV.

Authors:  Juan Martin-Serrano; Mark Marsh
Journal:  Cell Host Microbe       Date:  2007-03-15       Impact factor: 21.023

8.  Ceramide triggers budding of exosome vesicles into multivesicular endosomes.

Authors:  Katarina Trajkovic; Chieh Hsu; Salvatore Chiantia; Lawrence Rajendran; Dirk Wenzel; Felix Wieland; Petra Schwille; Britta Brügger; Mikael Simons
Journal:  Science       Date:  2008-02-29       Impact factor: 47.728

9.  Solution structure of the ESCRT-I and -II supercomplex: implications for membrane budding and scission.

Authors:  Evzen Boura; Bartosz Różycki; Hoi Sung Chung; Dawn Z Herrick; Bertram Canagarajah; David S Cafiso; William A Eaton; Gerhard Hummer; James H Hurley
Journal:  Structure       Date:  2012-05-09       Impact factor: 5.006

10.  ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting.

Authors:  Michael R Dores; Buxin Chen; Huilan Lin; Unice J K Soh; May M Paing; William A Montagne; Timo Meerloo; JoAnn Trejo
Journal:  J Cell Biol       Date:  2012-04-30       Impact factor: 10.539
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  84 in total

Review 1.  ESCRTs are everywhere.

Authors:  James H Hurley
Journal:  EMBO J       Date:  2015-08-25       Impact factor: 11.598

Review 2.  Circulating Exosomes of Neuronal Origin as Potential Early Biomarkers for Development of Stroke.

Authors:  Ghada Yousif; Shahnaz Qadri; Mahmoud Haik; Yousef Haik; Aijaz Sultan Parray; Ashfaq Shuaib
Journal:  Mol Diagn Ther       Date:  2021-01-16       Impact factor: 4.074

Review 3.  Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets.

Authors:  Gyongyi Szabo; Fatemeh Momen-Heravi
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2017-06-21       Impact factor: 46.802

4.  Port-to-port delivery: Mobilization of toxic sphingolipids via extracellular vesicles.

Authors:  Giuseppe Scesa; Ana Lis Moyano; Ernesto R Bongarzone; Maria I Givogri
Journal:  J Neurosci Res       Date:  2016-11       Impact factor: 4.164

Review 5.  Extracellular vesicles as potential biomarkers for alcohol- and drug-induced liver injury and their therapeutic applications.

Authors:  Young-Eun Cho; Byoung-Joon Song; Mohammed Akbar; Moon-Chang Baek
Journal:  Pharmacol Ther       Date:  2018-04-03       Impact factor: 12.310

Review 6.  Pathobiology of biliary epithelia.

Authors:  Angela C Cheung; Maria J Lorenzo Pisarello; Nicholas F LaRusso
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2017-07-15       Impact factor: 5.187

7.  Primed mesenchymal stem cells package exosomes with metabolites associated with immunomodulation.

Authors:  Megan R Showalter; Benjamin Wancewicz; Oliver Fiehn; Joehleen A Archard; Shannon Clayton; Joseph Wagner; Peter Deng; Julian Halmai; Kyle D Fink; Gerhard Bauer; Brian Fury; Nicholas H Perotti; Michelle Apperson; Janelle Butters; Peter Belafsky; Gregory Farwell; Maggie Kuhn; Jan A Nolta; Johnathon D Anderson
Journal:  Biochem Biophys Res Commun       Date:  2019-03-26       Impact factor: 3.575

8.  Copper-64 Labeled PEGylated Exosomes for In Vivo Positron Emission Tomography and Enhanced Tumor Retention.

Authors:  Sixiang Shi; Tingting Li; Xiaofei Wen; Sherry Y Wu; Chiyi Xiong; Jun Zhao; Victor R Lincha; Diana S Chow; Yiyao Liu; Anil K Sood; Chun Li
Journal:  Bioconjug Chem       Date:  2019-09-27       Impact factor: 4.774

Review 9.  Extracellular vesicles in liver pathobiology: Small particles with big impact.

Authors:  Petra Hirsova; Samar H Ibrahim; Vikas K Verma; Leslie A Morton; Vijay H Shah; Nicholas F LaRusso; Gregory J Gores; Harmeet Malhi
Journal:  Hepatology       Date:  2016-10-20       Impact factor: 17.425

Review 10.  Membrane fission reactions of the mammalian ESCRT pathway.

Authors:  John McCullough; Leremy A Colf; Wesley I Sundquist
Journal:  Annu Rev Biochem       Date:  2013-03-18       Impact factor: 23.643
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