Literature DB >> 22740750

Remission of chronic, advanced heart failure after left ventricular unloading with an implantable left ventricular assist device.

Zumrut T Demirozu1, O H Frazier.   

Abstract

We describe the case of a 35-year-old man with severe, dilated idiopathic cardiomyopathy who was placed on the waiting list for cardiac transplantation. While awaiting transplantation, his heart failure decompensated to such a degree that left ventricular assist device support was necessary. He did well on device support until a pump-pocket infection (methicillin-resistant coagulase-negative staphylococci) developed at 10 months. At that time, echocardiograms showed normal heart size and an ejection fraction of 0.45 to 0.49 without pump support. The pump was, therefore, explanted emergently. The patient has remained clinically stable with preserved ventricular function nearly 13 years after the explantation procedure.

Entities:  

Keywords:  Cardiomyopathy, dilated/complications/physiopathology; cardiovascular agents/therapeutic use; device removal; heart failure/therapy; heart-assist devices; treatment outcome; ventricular dysfunction, left/physiopathology

Mesh:

Year:  2012        PMID: 22740750      PMCID: PMC3384055     

Source DB:  PubMed          Journal:  Tex Heart Inst J        ISSN: 0730-2347


  9 in total

1.  Long-term use of a left ventricular assist device for end-stage heart failure.

Authors:  E A Rose; A C Gelijns; A J Moskowitz; D F Heitjan; L W Stevenson; W Dembitsky; J W Long; D D Ascheim; A R Tierney; R G Levitan; J T Watson; P Meier; N S Ronan; P A Shapiro; R M Lazar; L W Miller; L Gupta; O H Frazier; P Desvigne-Nickens; M C Oz; V L Poirier
Journal:  N Engl J Med       Date:  2001-11-15       Impact factor: 91.245

2.  Long-term results in patients with idiopathic dilated cardiomyopathy after weaning from left ventricular assist devices.

Authors:  Michael Dandel; Yuguo Weng; Henryk Siniawski; Evgenij Potapov; Hans B Lehmkuhl; Roland Hetzer
Journal:  Circulation       Date:  2005-08-30       Impact factor: 29.690

3.  Prolonged bed rest in the treatment of the dilated heart.

Authors:  G E Burch; J J Walsh; V J Ferrans; R Hibbs
Journal:  Circulation       Date:  1965-11       Impact factor: 29.690

4.  Midterm follow-up of patients who underwent removal of a left ventricular assist device after cardiac recovery from end-stage dilated cardiomyopathy.

Authors:  R Hetzer; J H Müller; Y G Weng; M Loebe; G Wallukat
Journal:  J Thorac Cardiovasc Surg       Date:  2000-11       Impact factor: 5.209

5.  Dobutamine stress echocardiography predicts myocardial improvement in patients supported by left ventricular assist devices (LVADs): hemodynamic and histologic evidence of improvement before LVAD explantation.

Authors:  Tehreen Khan; Reynolds M Delgado; Brano Radovancevic; Guillermo Torre-Amione; Jackie Abrams; Kathy Miller; Timothy Myers; Kristen Okerberg; Sonny J Stetson; Igor Gregoric; Antonita Hernandez; O H Frazier
Journal:  J Heart Lung Transplant       Date:  2003-02       Impact factor: 10.247

6.  Left ventricular assist device and drug therapy for the reversal of heart failure.

Authors:  Emma J Birks; Patrick D Tansley; James Hardy; Robert S George; Christopher T Bowles; Margaret Burke; Nicholas R Banner; Asghar Khaghani; Magdi H Yacoub
Journal:  N Engl J Med       Date:  2006-11-02       Impact factor: 91.245

7.  Advanced heart failure treated with continuous-flow left ventricular assist device.

Authors:  Mark S Slaughter; Joseph G Rogers; Carmelo A Milano; Stuart D Russell; John V Conte; David Feldman; Benjamin Sun; Antone J Tatooles; Reynolds M Delgado; James W Long; Thomas C Wozniak; Waqas Ghumman; David J Farrar; O Howard Frazier
Journal:  N Engl J Med       Date:  2009-11-17       Impact factor: 91.245

8.  Improved left ventricular function after chronic left ventricular unloading.

Authors:  O H Frazier; C R Benedict; B Radovancevic; R J Bick; P Capek; W E Springer; M P Macris; R Delgado; L M Buja
Journal:  Ann Thorac Surg       Date:  1996-09       Impact factor: 4.330

9.  Heart failure reversal by ventricular unloading in patients with chronic cardiomyopathy: criteria for weaning from ventricular assist devices.

Authors:  Michael Dandel; Yuguo Weng; Henryk Siniawski; Alexander Stepanenko; Thomas Krabatsch; Evgenij Potapov; Hans B Lehmkuhl; Christoph Knosalla; Roland Hetzer
Journal:  Eur Heart J       Date:  2010-10-07       Impact factor: 29.983

  9 in total
  1 in total

Review 1.  Anastasis: recovery from the brink of cell death.

Authors:  Ho Man Tang; Ho Lam Tang
Journal:  R Soc Open Sci       Date:  2018-09-19       Impact factor: 2.963

  1 in total

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