Literature DB >> 22707064

Prevalence and risk factors of radiographic vertebral fractures in elderly Chinese men and women: results of Mr. OS (Hong Kong) and Ms. OS (Hong Kong) studies.

A W L Kwok1, J-S Gong, Y-X J Wang, J C S Leung, T Kwok, J F Griffith, P C Leung.   

Abstract

UNLABELLED: This study investigated the prevalence of radiographic vertebral fractures using Genant's semiquantitative (SQ) scoring system in elderly Chinese men (n = 2,000; mean age, 72.4 years) and women (n = 2,000; mean age, 72.6 years). Vertebral deformities had similar prevalence in elderly men (14.9 %) and women (16.5 %). Majority of the deformities in men were mild (9.9 %, grade = 1). The prevalence of vertebral fractures (grade ≥ 2) was 5.0 % among men and 12.1 % among women.
INTRODUCTION: Vertebral fracture is a serious consequence of osteoporosis and is often under-diagnosed. Researches on different ethnicities and territories to estimate the prevalence of vertebral fractures and to identify the risk factors are necessary.
METHODS: Mr. OS (Hong Kong) and Ms. OS (Hong Kong) represent the first large-scale cohort studies ever conducted on bone health in elderly Chinese men (n = 2,000) and women (n = 2,000). The current study investigated the prevalence of radiographic vertebral fractures in these subjects using Genant's SQ scoring system and identified risk factors for vertebral fractures.
RESULTS: The radiographs of all men (mean age, 72.4 years) and women (mean age, 72.6 years) were obtained. Six hundred twenty-seven subjects (15.7 %) had at least one vertebral deformity (SQ grade ≥ 1), including 297 men (14.9 %) and 330 women (16.5 %, p = 0.151). Three hundred forty-two participants (8.6 %) were defined as having at least one vertebra fracture (SQ grade ≥ 2), consisted of 100 men (5.0 %) and 242 women (12.1 %, p < 0.001). Older age, lower bone mineral density, lower physical activity, lower grip strength, fracture history, and low back pain were significantly associated with higher vertebral fracture rate for both men and women.
CONCLUSION: Vertebral deformity had similar prevalence in older men and women, while vertebral fracture was more common in women. Majority of deformities in men was mild. The vertebral deformity prevalence of women from this study is similar to previous reports of other East Asian women and Latin American women.

Entities:  

Mesh:

Year:  2012        PMID: 22707064     DOI: 10.1007/s00198-012-2040-8

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  43 in total

1.  Relationship between gender, bone mineral density, and disc degeneration in the lumbar spine: a study in elderly subjects using an eight-level MRI-based disc degeneration grading system.

Authors:  Y-X J Wang; J F Griffith; H T Ma; A W L Kwok; J C S Leung; D K W Yeung; A T Ahuja; P C Leung
Journal:  Osteoporos Int       Date:  2010-03-30       Impact factor: 4.507

2.  Defining incident vertebral deformity: a prospective comparison of several approaches. The Study of Osteoporotic Fractures Research Group.

Authors:  D M Black; L Palermo; M C Nevitt; H K Genant; L Christensen; S R Cummings
Journal:  J Bone Miner Res       Date:  1999-01       Impact factor: 6.741

3.  Assessment of total energy expenditure in a Chinese population by a physical activity questionnaire: examination of validity.

Authors:  B Liu; J Woo; N Tang; K Ng; R Ip; A Yu
Journal:  Int J Food Sci Nutr       Date:  2001-05       Impact factor: 3.833

4.  The determinants of bone mineral density in Chinese men--results from Mr. Os (Hong Kong), the first cohort study on osteoporosis in Asian men.

Authors:  E M C Lau; P C Leung; T Kwok; J Woo; H Lynn; E Orwoll; S Cummings; J Cauley
Journal:  Osteoporos Int       Date:  2005-09-21       Impact factor: 4.507

5.  Underdiagnosis of vertebral fractures is a worldwide problem: the IMPACT study.

Authors:  Pierre D Delmas; Lex van de Langerijt; Nelson B Watts; Richard Eastell; Harry Genant; Andreas Grauer; David L Cahall
Journal:  J Bone Miner Res       Date:  2004-12-06       Impact factor: 6.741

6.  Vertebral deformity in chinese men: prevalence, risk factors, bone mineral density, and body composition measurements.

Authors:  E M Lau; Y H Chan; M Chan; J Woo; J Griffith; H H Chan; P C Leung
Journal:  Calcif Tissue Int       Date:  2000-01       Impact factor: 4.333

7.  Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial.

Authors:  P D Delmas; H K Genant; G G Crans; J L Stock; M Wong; E Siris; J D Adachi
Journal:  Bone       Date:  2003-10       Impact factor: 4.398

8.  The prevalence of radiographic vertebral fractures in Latin American countries: the Latin American Vertebral Osteoporosis Study (LAVOS).

Authors:  P Clark; F Cons-Molina; M Deleze; S Ragi; L Haddock; J R Zanchetta; J J Jaller; L Palermo; J O Talavera; D O Messina; J Morales-Torres; J Salmeron; A Navarrete; E Suarez; C M Pérez; S R Cummings
Journal:  Osteoporos Int       Date:  2008-06-26       Impact factor: 4.507

Review 9.  Diagnosis of osteoporosis and assessment of fracture risk.

Authors:  John A Kanis
Journal:  Lancet       Date:  2002-06-01       Impact factor: 79.321

10.  Prevalence of vertebral fractures on chest radiographs of elderly African American and Caucasian women.

Authors:  D Lansdown; B Bennet; S Thiel; O Ahmed; L Dixon; T J Vokes
Journal:  Osteoporos Int       Date:  2011-08       Impact factor: 4.507

View more
  48 in total

1.  The Predictive Value of Sarcopenia and Falls for 2-Year Major Osteoporotic Fractures in Community-Dwelling Older Adults.

Authors:  Yi Su; Freddy M H Lam; Jason Leung; Wing-Hoi Cheung; Suzanne C Ho; Timothy Kwok
Journal:  Calcif Tissue Int       Date:  2020-05-30       Impact factor: 4.333

2.  The protocol for the Prospective Urban Rural Epidemiology China Action on Spine and Hip status study.

Authors:  Kai Li; Yong Zhang; Ling Wang; Yang-Yang Duanmu; Wei Tian; Hui Chen; Lu Yin; Jian Bo; Yang Wang; Wei Li; Li He; Wen-Hua Zhao; Shao-Qi Xu; Lin-Fen Zhao; Jun Zhou; Feng-Zhe Wang; Yu Liu; Lei Zhu; Yi-Zhong Chen; Xiao-Lin Zhang; Xiao-Guang Hao; Zhi-Wei Shi; Jun-Ying Wang; Ji-Man Shao; Zhi-Jian Chen; Ren-Sheng Lei; Gang Ning; Qian Zhao; Yong-Hong Jiang; Ya-Hong Zhi; Bao-Qing Li; Xiao Chen; Quan-Yong Xiang; Liang Wang; Yuan-Zheng Ma; Shi-Wei Liu; Xiao-Guang Cheng
Journal:  Quant Imaging Med Surg       Date:  2018-08

3.  Situational risk factors for fall-related vertebral fractures in older men and women.

Authors:  W-Y Yu; H-F Hwang; C-Y Chen; M-R Lin
Journal:  Osteoporos Int       Date:  2021-01-07       Impact factor: 4.507

4.  Impact of femoral neck and lumbar spine BMD discordances on FRAX probabilities in women: a meta-analysis of international cohorts.

Authors:  H Johansson; J A Kanis; A Odén; W D Leslie; S Fujiwara; C C Glüer; H Kroger; A Z LaCroix; E Lau; L J Melton; J A Eisman; T W O'Neill; D Goltzman; D M Reid; E McCloskey
Journal:  Calcif Tissue Int       Date:  2014-09-04       Impact factor: 4.333

5.  Self-reported everyday physical activities in older people with osteoporotic vertebral fractures: a systematic review and meta-analysis.

Authors:  U A Al-Sari; J H Tobias; E M Clark
Journal:  Osteoporos Int       Date:  2017-11-03       Impact factor: 4.507

6.  Prediction models of prevalent radiographic vertebral fractures among older women.

Authors:  John T Schousboe; Harold R Rosen; Tamara J Vokes; Jane A Cauley; Steven R Cummings; Michael Nevitt; Dennis M Black; Eric S Orwoll; Deborah M Kado; Kristine E Ensrud
Journal:  J Clin Densitom       Date:  2014-02-25       Impact factor: 2.617

7.  Prediction models of prevalent radiographic vertebral fractures among older men.

Authors:  John T Schousboe; Harold R Rosen; Tamara J Vokes; Jane A Cauley; Steven R Cummings; Michael C Nevitt; Dennis M Black; Eric S Orwoll; Deborah M Kado; Kristine E Ensrud
Journal:  J Clin Densitom       Date:  2013-11-27       Impact factor: 2.617

8.  The added value of trabecular bone score to FRAX® to predict major osteoporotic fractures for clinical use in Chinese older people: the Mr. OS and Ms. OS cohort study in Hong Kong.

Authors:  Y Su; J Leung; D Hans; O Lamy; T Kwok
Journal:  Osteoporos Int       Date:  2016-08-26       Impact factor: 4.507

9.  Prevalence and risk factors associated with low-impact fractures in men with rheumatoid arthritis.

Authors:  José Carlos Amaral Filho; Marcelo Medeiros Pinheiro; Charlles Heldan de Moura Castro; Vera Lúcia Szejnfeld
Journal:  Clin Rheumatol       Date:  2013-11-14       Impact factor: 2.980

10.  The effect of physical activity on dose-relationship between serum 25-hydroxyvitamin D and cardiovascular health events in older adults.

Authors:  Yi Su; Jason Leung; Jenny Lee; Kin-Fai Ho; Timothy Kwok
Journal:  Nutr Metab Cardiovasc Dis       Date:  2019-12-14       Impact factor: 4.222

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.