Literature DB >> 22706928

Anaesthetic drug administration as a potential contributor to healthcare-associated infections: a prospective simulation-based evaluation of aseptic techniques in the administration of anaesthetic drugs.

Derryn A Gargiulo1, Janie Sheridan, Craig S Webster, Simon Swift, Jane Torrie, Jennifer Weller, Kaylene Henderson, Jacqueline Hannam, Alan F Merry.   

Abstract

OBJECTIVE: To evaluate the possibility that anaesthetists are administering potentially pathogenic micro-organisms to their patients.
DESIGN: Prospective microbiological and observational study in a realistic simulated setting. PARTICIPANTS: Ten anaesthetists supported by 10 anaesthetic technicians. PRIMARY OUTCOME MEASURE: The presence or absence of organisms cultured from sterile intravenous bags used to collect drugs injected during the simulated cases and from the needles and the contents of the syringes used. The authors also observed the aseptic techniques used.
RESULTS: Organisms were isolated from five of 38 (13%) bags from five of 20 simulated cases anaesthetised by four of 10 anaesthetists, 10 of 197 (5%) syringes and six of 17 (35%) needles. None of the anaesthetists washed their hands prior to entry, used the hand gel provided, disinfected the phial septa before drawing up drugs or disinfected the intravenous ports on the intravenous administration set before use. One was seen to recap a needle left on a syringe for possible reuse. Three participants were observed to place equipment such as stethoscopes, drug charts and pens on top of their inuse drug trays.
CONCLUSION: The administration of intravenous drugs during anaesthesia may be an important factor in the genesis (or potentially the prevention) of healthcare-associated infection. These observations suggest room for improvement in the aseptic techniques of at least some anaesthetists when preparing and administering intravenous drugs. Confirmation of these findings in clinical settings is needed. STUDY REGISTRY NUMBER (FOR THE VASER STUDY): Australian New Zealand Clinical Trials Registry: Ref: ACTRN 12609000530224, https://www.anzctr.org.au/registry/trial_review.aspx?ID=308128; note that the work presented here is a subset of the registered trial and its outcomes were not included in this registration.

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Year:  2012        PMID: 22706928     DOI: 10.1136/bmjqs-2012-000814

Source DB:  PubMed          Journal:  BMJ Qual Saf        ISSN: 2044-5415            Impact factor:   7.035


  8 in total

1.  An investigation into the stability and sterility of citric acid solutions used for cough reflex testing.

Authors:  James R Falconer; Zimei Wu; Hugo Lau; Joanna Suen; Lucy Wang; Sarah Pottinger; Elaine Lee; Nawar Alazawi; Molly Kallesen; Derryn A Gargiulo; Simon Swift; Darren Svirskis
Journal:  Dysphagia       Date:  2014-08-24       Impact factor: 3.438

2.  Development and content validation of an assessment tool for medicine compounding on hospital wards.

Authors:  Eeva Suvikas-Peltonen; Eija Granfors; Ercan Celikkayalar; Raisa Laaksonen; Joni Palmgren; Marja Airaksinen
Journal:  Int J Clin Pharm       Date:  2016-11-05

3.  Bacterial Contamination of Anaesthetic and Vasopressor Drugs in the Operating Theatres: Ameliyathanelerde Anestetik ve Vazopressör İlaçların Bakteriyel Kontaminasyonu.

Authors:  Rongrong Rueangchira-Urai; Panthila Rujirojindakul; Alan Frederick Geater; Edward McNeil
Journal:  Turk J Anaesthesiol Reanim       Date:  2017-02-01

4.  Existing Knowledge of Medication Error Must Be Better Translated Into Improved Patient Safety.

Authors:  Craig S Webster
Journal:  Front Med (Lausanne)       Date:  2022-05-17

Review 5.  A systematic review and meta-analysis of microbial contamination of parenteral medication prepared in a clinical versus pharmacy environment.

Authors:  Karin H M Larmené-Beld; Henderik W Frijlink; Katja Taxis
Journal:  Eur J Clin Pharmacol       Date:  2019-01-25       Impact factor: 2.953

6.  Incorrect aseptic techniques in medicine preparation and recommendations for safer practices: a systematic review.

Authors:  Eeva Suvikas-Peltonen; Suvi Hakoinen; Ercan Celikkayalar; Raisa Laaksonen; Marja Airaksinen
Journal:  Eur J Hosp Pharm       Date:  2016-10-12

7.  The effect of implementing an aseptic practice bundle for anaesthetists to reduce postoperative infections, the Anaesthetists Be Cleaner (ABC) study: protocol for a stepped wedge, cluster randomised, multi-site trial.

Authors:  Alan F Merry; Derryn A Gargiulo; Ian Bissett; David Cumin; Kerry English; Christopher Frampton; Richard Hamblin; Jacqueline Hannam; Matthew Moore; Papaarangi Reid; Sally Roberts; Elsa Taylor; Simon J Mitchell
Journal:  Trials       Date:  2019-06-10       Impact factor: 2.279

8.  Anesthesia Workspace Cleanliness and Safety: Implementation of a Novel Syringe Bracket Using 3D Printing Techniques.

Authors:  Dustin R Long; Allison Doney; Devan L Bartels; Crystal E Tan; Puneet K Sayal; Thomas A Anderson; Aalok V Agarwala
Journal:  Anesthesiol Res Pract       Date:  2019-07-01
  8 in total

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