| Literature DB >> 226889 |
L F Liu, C C Liu, B M Alberts.
Abstract
A novel ATP-dependent DNA topoisomerase which makes reversible double-strand breaks in the DNA double helix has been purified to near homogeneity from T4 bacteriophage-infected Escherichia coli cells. Genetic data suggest that this activity is essential for initiating T4 DNA replication forks in vivo.Entities:
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Year: 1979 PMID: 226889 DOI: 10.1038/281456a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962