Literature DB >> 22688704

In vitro explant culture and related protocols for the study of mouse retinal development.

Kangxin Jin1, Mengqing Xiang.   

Abstract

The mouse retina is composed of many cell types and subtypes with distinct morphology and function; how these cells are differentiated from the multipotent progenitors is still largely unknown. Retinal in vitro explant culture has proven to be a useful tool to study the molecular and cellular mechanisms underlying retinal development. Here, we provide detailed descriptions about how to prepare retroviruses, dissect retinal cups, perform in vitro explant culture, and collect explant samples.

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Year:  2012        PMID： 22688704     DOI： 10.1007/978-1-61779-848-1_10

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  6 in total

1.  Developmental stage-specific proliferation and retinoblastoma genesis in RB-deficient human but not mouse cone precursors.

Authors:  Hardeep P Singh; Sijia Wang; Kevin Stachelek; Sunhye Lee; Mark W Reid; Matthew E Thornton; Cheryl Mae Craft; Brendan H Grubbs; David Cobrinik
Journal:  Proc Natl Acad Sci U S A       Date:  2018-09-13       Impact factor: 11.205

2.  Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development.

Authors:  Yufeng Lu; Fion Shiau; Wenyang Yi; Suying Lu; Qian Wu; Joel D Pearson; Alyssa Kallman; Suijuan Zhong; Thanh Hoang; Zhentao Zuo; Fangqi Zhao; Mei Zhang; Nicole Tsai; Yan Zhuo; Sheng He; Jun Zhang; Genevieve L Stein-O'Brien; Thomas D Sherman; Xin Duan; Elana J Fertig; Loyal A Goff; Donald J Zack; James T Handa; Tian Xue; Rod Bremner; Seth Blackshaw; Xiaoqun Wang; Brian S Clark
Journal:  Dev Cell       Date:  2020-05-07       Impact factor: 12.270

3.  Requirement of the Mowat-Wilson Syndrome Gene Zeb2 in the Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.

Authors:  Wen Wei; Bin Liu; Haisong Jiang; Kangxin Jin; Mengqing Xiang
Journal:  Mol Neurobiol       Date:  2018-06-19       Impact factor: 5.590

4.  Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis.

Authors:  Kangxin Jin; Haisong Jiang; Dongchang Xiao; Min Zou; Jun Zhu; Mengqing Xiang
Journal:  Mol Brain       Date:  2015-05-13       Impact factor: 4.041

5.  Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.

Authors:  Dongchang Xiao; Kangxin Jin; Mengqing Xiang
Journal:  Front Mol Neurosci       Date:  2018-08-06       Impact factor: 5.639

6.  Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity.

Authors:  Joel D Pearson; Katherine Huang; Marek Pacal; Sean R McCurdy; Suying Lu; Arthur Aubry; Tao Yu; Kristine M Wadosky; Letian Zhang; Tao Wang; Alex Gregorieff; Mohammad Ahmad; Helen Dimaras; Ellen Langille; Susan P C Cole; Philippe P Monnier; Benjamin H Lok; Ming-Sound Tsao; Nagako Akeno; Daniel Schramek; Kathryn A Wikenheiser-Brokamp; Erik S Knudsen; Agnieszka K Witkiewicz; Jeffrey L Wrana; David W Goodrich; Rod Bremner
Journal:  Cancer Cell       Date:  2021-07-21       Impact factor: 31.743
  6 in total

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