| Literature DB >> 22688088 |
Alister J Hart1, Paul D Quinn, Ferdinand Lali, Barry Sampson, John A Skinner, Jonathan J Powell, John Nolan, Keith Tucker, Simon Donell, Adrienne Flanagan, J Fred W Mosselmans.
Abstract
Some types of metal-on-metal (MOM) hip replacements have unacceptably high rates of failure, such as the Ultima TPS MOM hip, with 13.8% failure at 5 years. This has been attributed to an inflammatory reaction following the release of cobalt (Co) and chromium (Cr) from the bearing surfaces and modular junctions. There is in vitro evidence that Co is more important than Cr in the inflammatory process, but there are no reported human tissue studies of the analysis of implant-derived metals.Entities:
Mesh：
Substances：
Year: 2012 PMID： 22688088 DOI： 10.1016/j.actbio.2012.05.003
Source DB: PubMed Journal: Acta Biomater ISSN： 1742-7061 Impact factor: 8.947