Literature DB >> 22676314

Behaviour problems, maternal internalising symptoms and family relations in families of adolescents and adults with fragile X syndrome.

J K Baker1, M M Seltzer, J S Greenberg.   

Abstract

BACKGROUND: Studies have linked the behaviour problems of children with fragile X syndrome (FXS) to maternal well-being, but less is known about how behaviour problems relate to important family factors such as marital satisfaction and family cohesion.
METHODS: Married mothers of 115 adolescents and adults with FXS completed questionnaires and interviews, and maternal CGG repeat length was obtained by medical/laboratory records or by blood analysis.
RESULTS: Indirect effects were present between behaviour problems and family variables in that behaviour problems were positively related to maternal internalising symptoms which were, in turn, negatively associated with both family cohesion and marital satisfaction. Direct associations between behaviour problems and family relationship variables were not significant.
CONCLUSIONS: Findings suggest the importance of intervening with behaviour problems in individuals with FXS and identify maternal mental health as a potentially powerful conduit for the effects of child behaviour on relationships within these families. Implications for targeted interventions are discussed.
© 2012 The Authors. Journal of Intellectual Disability Research © 2012 Blackwell Publishing Ltd.

Entities:  

Mesh:

Year:  2012        PMID: 22676314      PMCID: PMC3443295          DOI: 10.1111/j.1365-2788.2012.01580.x

Source DB:  PubMed          Journal:  J Intellect Disabil Res        ISSN: 0964-2633


  36 in total

1.  Adult and geriatric normative data and validation of the profile of mood states.

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2.  Differential sensitivity to life stress in FMR1 premutation carrier mothers of children with fragile X syndrome.

Authors:  Marsha Mailick Seltzer; Erin T Barker; Jan S Greenberg; Jinkuk Hong; Christopher Coe; David Almeida
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3.  Behavioral phenotype of fragile X syndrome in adolescence and adulthood.

Authors:  Leann E Smith; Erin T Barker; Marsha Mailick Seltzer; Leonard Abbeduto; Jan S Greenberg
Journal:  Am J Intellect Dev Disabil       Date:  2012-01

4.  Family experiences associated with a child's diagnosis of fragile X or Down syndrome: evidence for disruption and resilience.

Authors:  Julie Poehlmann; Melissa Clements; Len Abbeduto; Venous Farsad
Journal:  Ment Retard       Date:  2005-08

5.  Behavioral treatment and normal educational and intellectual functioning in young autistic children.

Authors:  O I Lovaas
Journal:  J Consult Clin Psychol       Date:  1987-02

6.  The contribution of marital quality to the well-being of parents of children with developmental disabilities.

Authors:  J Kersh; T T Hedvat; P Hauser-Cram; M E Warfield
Journal:  J Intellect Disabil Res       Date:  2006-12

7.  Latent class analysis of anxiety and depressive symptoms of the Youth Self-Report in a general population sample of young adolescents.

Authors:  Natasja D J van Lang; Robert F Ferdinand; Johan Ormel; Frank C Verhulst
Journal:  Behav Res Ther       Date:  2005-08-24

8.  Marital Quality and Families of Children with Developmental Disabilities.

Authors:  Sigan L Hartley; Marsha Mailick Seltzer; Erin T Barker; Jan S Greenberg
Journal:  Int Rev Res Dev Disabil       Date:  2011

Review 9.  Intellectual disabilities and child psychiatry: looking to the future.

Authors:  Robert M Hodapp; Elisabeth M Dykens
Journal:  J Child Psychol Psychiatry       Date:  2009-01       Impact factor: 8.982

10.  Cortisol response to behavior problems in FMR1 premutation mothers of adolescents and adults with fragile X syndrome: A diathesis-stress model.

Authors:  Sigan L Hartley; Marsha Mailick Seltzer; Jinkuk Hong; Jan S Greenberg; Leann Smith; David Almeida; Chris Coe; Leonard Abbeduto
Journal:  Int J Behav Dev       Date:  2012-01
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  18 in total

1.  Change in the Behavioral Phenotype of Adolescents and Adults with FXS: Role of the Family Environment.

Authors:  Leann E Smith; Jinkuk Hong; Jan S Greenberg; Marsha R Mailick
Journal:  J Autism Dev Disord       Date:  2016-05

Review 2.  Epigenetics, autism spectrum, and neurodevelopmental disorders.

Authors:  Sampathkumar Rangasamy; Santosh R D'Mello; Vinodh Narayanan
Journal:  Neurotherapeutics       Date:  2013-10       Impact factor: 7.620

3.  Executive Functioning Mediates the Effect of Behavioral Problems on Depression in Mothers of Children With Developmental Disabilities.

Authors:  Wai Chan; Leann E Smith; Jan S Greenberg; Jinkuk Hong; Marsha R Mailick
Journal:  Am J Intellect Dev Disabil       Date:  2017-01

4.  The Future of Fragile X Syndrome: CDC Stakeholder Meeting Summary.

Authors:  Catharine Riley; Marsha Mailick; Elizabeth Berry-Kravis; Julie Bolen
Journal:  Pediatrics       Date:  2017-06       Impact factor: 7.124

Review 5.  Public Health Literature Review of Fragile X Syndrome.

Authors:  Melissa Raspa; Anne C Wheeler; Catharine Riley
Journal:  Pediatrics       Date:  2017-06       Impact factor: 7.124

6.  Frequency and correlates of service access among youth with autism transitioning to adulthood.

Authors:  Julie Lounds Taylor; Natalie A Henninger
Journal:  J Autism Dev Disord       Date:  2015-01

7.  Trajectories of Change in the Behavioral and Health Phenotype of Adolescents and Adults with Fragile X Syndrome and Intellectual Disability: Longitudinal Trends Over a Decade.

Authors:  Lauren V Usher; Leann S DaWalt; Jinkuk Hong; Jan S Greenberg; Marsha R Mailick
Journal:  J Autism Dev Disord       Date:  2020-08

8.  Maternal Pragmatic Language Difficulties in the FMR1 Premutation and the Broad Autism Phenotype: Associations with Individual and Family Outcomes.

Authors:  Jessica Klusek; Angela John Thurman; Leonard Abbeduto
Journal:  J Autism Dev Disord       Date:  2021-04-04

9.  Stress and genetics influence hair cortisol in FMR1 premutation carrier mothers of children with fragile X syndrome.

Authors:  Jinkuk Hong; Amita Kapoor; Leann Smith DaWalt; Nell Maltman; Bryan Kim; Elizabeth M Berry-Kravis; David Almeida; Christopher Coe; Marsha Mailick
Journal:  Psychoneuroendocrinology       Date:  2021-05-13       Impact factor: 4.693

10.  Parental stress and adjustment in the context of rare genetic syndromes: A scoping review.

Authors:  Jacqueline Fitzgerald; Louise Gallagher
Journal:  J Intellect Disabil       Date:  2021-04-19
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