Literature DB >> 22674325

Is it time for a metagenomic basis of therapeutics?

Henry J Haiser1, Peter J Turnbaugh.   

Abstract

The trillions of microbes associated with the human body are a key part of a comprehensive view of pharmacology. A mechanistic understanding of how the gut microbiota directly and indirectly affects drug metabolism is beginning to emerge.

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Year:  2012        PMID: 22674325     DOI: 10.1126/science.1224396

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  51 in total

1.  Microbial determinants of biochemical individuality and their impact on toxicology and pharmacology.

Authors:  Andrew D Patterson; Peter J Turnbaugh
Journal:  Cell Metab       Date:  2014-08-21       Impact factor: 27.287

Review 2.  Experimental approaches for defining functional roles of microbes in the human gut.

Authors:  Gautam Dantas; Morten O A Sommer; Patrick H Degnan; Andrew L Goodman
Journal:  Annu Rev Microbiol       Date:  2013       Impact factor: 15.500

Review 3.  Intestinal microbiome and digoxin inactivation: meal plan for digoxin users?

Authors:  Lingeng Lu; Yixing Wu; Lingjun Zuo; Xingguang Luo; Peter J Large
Journal:  World J Microbiol Biotechnol       Date:  2013-10-09       Impact factor: 3.312

Review 4.  Emerging roles of the microbiome in cancer.

Authors:  Scott J Bultman
Journal:  Carcinogenesis       Date:  2013-12-03       Impact factor: 4.944

5.  Gut microbes may facilitate insect herbivory of chemically defended plants.

Authors:  Tobin J Hammer; M Deane Bowers
Journal:  Oecologia       Date:  2015-05-05       Impact factor: 3.225

Review 6.  Microbiota in cancer development and treatment.

Authors:  Muhammad Hassan Raza; Kamni Gul; Abida Arshad; Naveeda Riaz; Usman Waheed; Abdul Rauf; Fahad Aldakheel; Shatha Alduraywish; Maqbool Ur Rehman; Muhammad Abdullah; Muhammad Arshad
Journal:  J Cancer Res Clin Oncol       Date:  2018-12-12       Impact factor: 4.553

7.  A complex microworld in the gut: gut microbiota and cardiovascular disease connectivity.

Authors:  Michael R Howitt; Wendy S Garrett
Journal:  Nat Med       Date:  2012-08       Impact factor: 53.440

Review 8.  Gut and root microbiota commonalities.

Authors:  Shamayim T Ramírez-Puebla; Luis E Servín-Garcidueñas; Berenice Jiménez-Marín; Luis M Bolaños; Mónica Rosenblueth; Julio Martínez; Marco Antonio Rogel; Ernesto Ormeño-Orrillo; Esperanza Martínez-Romero
Journal:  Appl Environ Microbiol       Date:  2012-10-26       Impact factor: 4.792

Review 9.  Symbiosis as a general principle in eukaryotic evolution.

Authors:  Angela E Douglas
Journal:  Cold Spring Harb Perspect Biol       Date:  2014-02-01       Impact factor: 10.005

10.  TLR signaling modulates side effects of anticancer therapy in the small intestine.

Authors:  Magdalena Frank; Eva Maria Hennenberg; Annette Eyking; Michael Rünzi; Guido Gerken; Paul Scott; Julian Parkhill; Alan W Walker; Elke Cario
Journal:  J Immunol       Date:  2015-01-14       Impact factor: 5.422

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