BACKGROUND: Previous studies have reported that a consistent proportion of patients with Essential Tremor may have psychiatric disorders but it is unclear whether these disorders are increased in frequency as compared to healthy subjects. METHODS: In a case-control study, we adopted the structured interviews for DSM-IV, SCID-I and SCID-II, to investigate psychiatric and personality disorders in 37 ET patients and 34 healthy subjects. As cognitive changes in ET may be a confounding factor we enrolled patients and healthy control subjects without cognitive dysfunction. RESULTS: SCID-I showed that Axis-I psychiatric disorders, mainly depressive disorders, were more frequent in ET patients (20 of 37; 54%) than in healthy subjects (8 of 34; 22%) (p < 0.01). Depressive disorders were more frequent in patients with a family history of ET (p < 0.05) in comparison to patients without a family history. SCID-II disclosed that the frequency of personality disorders was similar in patients with ET and healthy subjects. CONCLUSION: Psychiatric disorders may be associated to the neurological manifestations of ET.
BACKGROUND: Previous studies have reported that a consistent proportion of patients with Essential Tremor may have psychiatric disorders but it is unclear whether these disorders are increased in frequency as compared to healthy subjects. METHODS: In a case-control study, we adopted the structured interviews for DSM-IV, SCID-I and SCID-II, to investigate psychiatric and personality disorders in 37 ET patients and 34 healthy subjects. As cognitive changes in ET may be a confounding factor we enrolled patients and healthy control subjects without cognitive dysfunction. RESULTS: SCID-I showed that Axis-I psychiatric disorders, mainly depressive disorders, were more frequent in ET patients (20 of 37; 54%) than in healthy subjects (8 of 34; 22%) (p < 0.01). Depressive disorders were more frequent in patients with a family history of ET (p < 0.05) in comparison to patients without a family history. SCID-II disclosed that the frequency of personality disorders was similar in patients with ET and healthy subjects. CONCLUSION:Psychiatric disorders may be associated to the neurological manifestations of ET.
Authors: Edward D Huey; Stephanie Cosentino; Silvia Chapman; Martina Azar; Brittany Rohl; Kathleen Collins; Sarah Morgan; Xinhua Liu; Elan D Louis Journal: Parkinsonism Relat Disord Date: 2018-02-20 Impact factor: 4.891
Authors: Jacob A Lafo; Ania Mikos; Paul C Mangal; Bonnie M Scott; Erin Trifilio; Michael S Okun; Dawn Bowers Journal: Parkinsonism Relat Disord Date: 2016-11-17 Impact factor: 4.891