| Literature DB >> 22648868 |
Yvonne E Chiu1, Beth A Drolet, Francine Blei, Manuel Carcao, Jason Fangusaro, Michael E Kelly, Alfons Krol, Sabra Lofgren, Anthony J Mancini, Denise W Metry, Michael Recht, Robert A Silverman, Wynnis L Tom, Elena Pope.
Abstract
Propranolol is a non-selective beta-adrenergic antagonist successfully used in a case of kaposiform hemangioendothelioma (KHE) associated with Kasabach-Merritt phenomenon (KMP). We report 11 patients treated with propranolol for KHE and the related variant tufted angioma (TA), six of whom also had KMP. The varied responses to treatment, with only 36% responding in our series, demonstrate the need for further study of this medication before routine use for these indications.Entities:
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Year: 2012 PMID: 22648868 PMCID: PMC3528889 DOI: 10.1002/pbc.24103
Source DB: PubMed Journal: Pediatr Blood Cancer ISSN: 1545-5009 Impact factor: 3.167