Literature DB >> 29285174

Kasabach-Merritt syndrome combined with hypercalcemia: A case report.

Runying Zou1, Fang Peng1, Tian Yu1, Saizhen Zeng1, Yalan You1, Keke Chen1, Hui Zou1, Xin Tian1, Chengguang Zhu1, Xiangling He1.   

Abstract

The present case report presented the diagnosis and treatment course of an infant diagnosed with Kasabach-Merritt syndrome (KMS) combined with hypercalcemia (HC). A 35-day-old infant with swelling on the upper right arm for >1 month and thrombocytopenia for 1 day was admitted to Hunan Provincial People's Hospital (Changsha, China) and a series of treatments, including γ-globulin impact, heparin anticoagulation, platelet transfusion, supplement of cryoprecipitate and fibrinogen following heparinization and inhabitation of vascular endothelial cell proliferation by propranolol, were performed. At 2 months after the initial admission to the hospital, surgery was conducted and the hemangioma was removed through pipeline arteriosclerosis embolization when the patient was hospitalized again with symptoms of vomiting and atrophy accompanied by HC. The level of blood calcium reduced to normal following surgery. Cases of KMS combined with HC are extremely rare and the most effective way to treat such cases is surgical resection of the hemangioma.

Entities:  

Keywords:  Kasabach-Merritt syndrome; hemangioma; hypercalcemia; thrombocytopenia

Year:  2017        PMID: 29285174      PMCID: PMC5740515          DOI: 10.3892/etm.2017.5332

Source DB:  PubMed          Journal:  Exp Ther Med        ISSN: 1792-0981            Impact factor:   2.447


  30 in total

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