Literature DB >> 22645102

The role of endovascular expertise in carotid artery stenting: results from the ALKK-CAS-Registry in 5,535 patients.

Stephan Staubach1, Ralph Hein-Rothweiler, Matthias Hochadel, Manuela Segerer, Ralf Zahn, Jens Jung, Gotthard Riess, Hubert Seggewiss, Andre Schneider, Thomas Fürste, Christian Gottkehaskamp, Harald Mudra.   

Abstract

PURPOSE: Several scientific committees have proposed an accentuation of operator minimal requirements before accreditation for carotid artery stenting is granted. The current study aims to identify potential effects from increasing site experience on periprocedural safety and outcome of carotid artery stenting (CAS).
METHODS: Between 1996 and December 2009, 5,535 procedures have been entered into the prospective, controlled ALKK-CAS-Registry. The total cohort was divided in four subgroups according to the consecutive patient order at each participating center: patients 1-49 (n = 1,485), 50-99 (n = 1,118), 100-199 (n = 1,521) and ≥200 (n = 1,411).
RESULTS: The median age of all patients was 71 years; 52.8 % had a symptomatic carotid stenosis. A decline in the rates of in-hospital major stroke (2.1, 1.9, 1.6, 0.9, p for trend 0.014) and of ipsilateral strokes (3.1, 2.4, 2.5, 1.6 %, p for trend 0.019) was substantiated with increasing site experience. This significant trend was preserved in the combined rate of major stroke and death (4.0, 3.2, 3.4, 2.4 %, p for trend 0.034). Apart from CAS experience, improvements in CAS technique, a decreasing number of symptomatic patients and an increasing number of procedures under embolic protection (each p for trend <0.05) might have contributed to these results.
CONCLUSIONS: The results show a gradual reduction of in-hospital stroke rates with increasing center experience. Extensive supervision of CAS learners and further promotion of proctorship programs seem to be essential.

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Year:  2012        PMID: 22645102     DOI: 10.1007/s00392-012-0479-4

Source DB:  PubMed          Journal:  Clin Res Cardiol        ISSN: 1861-0684            Impact factor:   5.460


  42 in total

1.  Endarterectomy versus stenting for carotid stenosis.

Authors:  Robert F Bonvini; Marc Righini
Journal:  N Engl J Med       Date:  2007-01-18       Impact factor: 91.245

2.  Thirty-day outcomes for carotid artery stenting in 6320 patients from 2 prospective, multicenter, high-surgical-risk registries.

Authors:  William A Gray; Seemant Chaturvedi; Patrick Verta
Journal:  Circ Cardiovasc Interv       Date:  2009-03-06       Impact factor: 6.546

3.  Immediate and late clinical outcomes of carotid artery stenting in patients with symptomatic and asymptomatic carotid artery stenosis: a 5-year prospective analysis.

Authors:  G S Roubin; G New; S S Iyer; J J Vitek; N Al-Mubarak; M W Liu; J Yadav; C Gomez; R E Kuntz
Journal:  Circulation       Date:  2001-01-30       Impact factor: 29.690

4.  Influence of site and operator characteristics on carotid artery stent outcomes: analysis of the CAPTURE 2 (Carotid ACCULINK/ACCUNET Post Approval Trial to Uncover Rare Events) clinical study.

Authors:  William A Gray; Kenneth A Rosenfield; Michael R Jaff; Seemant Chaturvedi; Lei Peng; Patrick Verta
Journal:  JACC Cardiovasc Interv       Date:  2011-02       Impact factor: 11.195

5.  Endovascular versus surgical treatment in patients with carotid stenosis in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): a randomised trial.

Authors: 
Journal:  Lancet       Date:  2001-06-02       Impact factor: 79.321

6.  Carotid artery stenting: first consensus document of the ICCS-SPREAD Joint Committee.

Authors:  Alberto Cremonesi; Carlo Setacci; Angelo Bignamini; Leonardo Bolognese; Francesco Briganti; Germano Di Sciascio; Domenico Inzitari; Gaetano Lanza; Luciano Lupattelli; Salvatore Mangiafico; Carlo Pratesi; Bernard Reimers; Stefano Ricci; Gianmarco de Donato; Ugo Ugolotti; Augusto Zaninelli; Gian Franco Gensini
Journal:  Stroke       Date:  2006-08-10       Impact factor: 7.914

7.  Carotid artery stenting in octogenarians: results from the ALKK Carotid Artery Stent (CAS) Registry.

Authors:  Ralf Zahn; Thomas Ischinger; Matthias Hochadel; Uwe Zeymer; Wolfgang Schmalz; Norbert Treese; Karl Eugen Hauptmann; Hubert Seggewiss; Ilse Janicke; Hartwig Haase; Harald Mudra; Jochen Senges
Journal:  Eur Heart J       Date:  2006-12-11       Impact factor: 29.983

8.  One-year clinical outcomes, midterm survival, and predictors of mortality after carotid stenting in elderly patients.

Authors:  Paul T L Chiam; Gary S Roubin; Georgia Panagopoulos; Sriram S Iyer; Richard M Green; Christina Brennan; Jiri J Vitek
Journal:  Circulation       Date:  2009-04-20       Impact factor: 29.690

9.  Carotid artery stenting: identification of risk factors for poor outcomes.

Authors:  Benjamin M Jackson; Sean J English; Ronald M Fairman; Jagajan Karmacharya; Jeffrey P Carpenter; Edward Y Woo
Journal:  J Vasc Surg       Date:  2008-05-23       Impact factor: 4.268

10.  Routine use of cerebral protection during carotid artery stenting: results of a multicenter registry of 753 patients.

Authors:  Bernhard Reimers; Michael Schlüter; Fausto Castriota; Thilo Tübler; Nicola Corvaja; Carlo Cernetti; Raffaella Manetti; Amedeo Picciolo; Francesco Liistro; Carlo Di Mario; Alberto Cremonesi; Joachim Schofer; Antonio Colombo
Journal:  Am J Med       Date:  2004-02-15       Impact factor: 4.965

View more
  6 in total

1.  [Carotid artery stenting: is there a volume-outcome correlation?].

Authors:  S Staubach; H Mudra
Journal:  Herz       Date:  2013-11       Impact factor: 1.443

2.  [GeCAS registry. Sense and purpose of a carotid percutaneous transluminal angioplasty register in the era of obligatory quality assurance].

Authors:  N Werner; R Zahn
Journal:  Herz       Date:  2013-11       Impact factor: 1.443

3.  [Current guidelines on carotid artery stenting. Critical evaluation].

Authors:  R Hein-Rothweiler; H Mudra
Journal:  Herz       Date:  2013-11       Impact factor: 1.443

4.  Complication rates and center enrollment volume in the carotid revascularization endarterectomy versus stenting trial.

Authors:  Nicole R Gonzales; Bart M Demaerschalk; Jenifer H Voeks; MeeLee Tom; George Howard; Alice J Sheffet; Lawrence Garcia; Daniel G Clair; John Barr; Steven Orlow; Thomas G Brott
Journal:  Stroke       Date:  2014-09-25       Impact factor: 7.914

5.  Predictors of minor versus major stroke during carotid artery stenting: results from the carotid artery stenting (CAS) registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK).

Authors:  Stephan Staubach; Ralph Hein-Rothweiler; Matthias Hochadel; Manuela Segerer; Ralf Zahn; Jens Jung; Gotthard Riess; Hubert Seggewiss; Andre Schneider; Thomas Fürste; Christian Gottkehaskamp; Harald Mudra
Journal:  Clin Res Cardiol       Date:  2014-01-11       Impact factor: 5.460

6.  [Carotid artery stenting technique].

Authors:  J Schofer; K Bijuklic
Journal:  Herz       Date:  2013-11       Impact factor: 1.443

  6 in total

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