Literature DB >> 22622145

Structural basis for oxygen sensing and signal transduction of the heme-based sensor protein Aer2 from Pseudomonas aeruginosa.

Hitomi Sawai1, Hiroshi Sugimoto, Yoshitsugu Shiro, Haruto Ishikawa, Yasuhisa Mizutani, Shigetoshi Aono.   

Abstract

The crystal structure of a truncated Aer2, a signal transducer protein from Pseudomonas aeruginosa, consisting of the heme-containing PAS and di-HAMP domains revealed that a distal tryptophan residue (Trp283) plays an important role in stabilizing the heme-bound O(2) and intra-molecular signal transduction upon O(2) binding.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22622145     DOI： 10.1039/c2cc32549g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  14 in total

Review 1.  Sensory Repertoire of Bacterial Chemoreceptors.

Authors:  Álvaro Ortega; Igor B Zhulin; Tino Krell
Journal:  Microbiol Mol Biol Rev       Date:  2017-10-25       Impact factor: 11.056

2.  Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling.

Authors:  Michael V Airola; Doowon Huh; Nattakan Sukomon; Joanne Widom; Ria Sircar; Peter P Borbat; Jack H Freed; Kylie J Watts; Brian R Crane
Journal:  J Mol Biol       Date:  2012-12-26       Impact factor: 5.469

3.  Gas Sensing and Signaling in the PAS-Heme Domain of the Pseudomonas aeruginosa Aer2 Receptor.

Authors:  Darysbel Garcia; Emilie Orillard; Mark S Johnson; Kylie J Watts
Journal:  J Bacteriol       Date:  2017-08-22       Impact factor: 3.490

4.  New Roles for HAMP Domains: the Tri-HAMP Region of Pseudomonas aeruginosa Aer2 Controls Receptor Signaling and Cellular Localization.

Authors:  Selina Anaya; Emilie Orillard; Suzanne E Greer-Phillips; Kylie J Watts
Journal:  J Bacteriol       Date:  2022-08-02       Impact factor: 3.476

Review 5.  Heme-based globin-coupled oxygen sensors: linking oxygen binding to functional regulation of diguanylate cyclase, histidine kinase, and methyl-accepting chemotaxis.

Authors:  Markéta Martínková; Kenichi Kitanishi; Toru Shimizu
Journal:  J Biol Chem       Date:  2013-08-08       Impact factor: 5.157

6.  An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.

Authors:  Mary Ortmayer; Pierre Lafite; Binuraj R K Menon; Tewes Tralau; Karl Fisher; Lukas Denkhaus; Nigel S Scrutton; Stephen E J Rigby; Andrew W Munro; Sam Hay; David Leys
Journal:  Nature       Date:  2016-11-16       Impact factor: 49.962

Review 7.  Pseudomonas aeruginosa as a Model To Study Chemosensory Pathway Signaling.

Authors:  Miguel A Matilla; David Martín-Mora; Jose A Gavira; Tino Krell
Journal:  Microbiol Mol Biol Rev       Date:  2021-01-13       Impact factor: 11.056

8.  Oxygen-Induced Conformational Changes in the PAS-Heme Domain of the Pseudomonas aeruginosa Aer2 Receptor.

Authors:  Emilie Orillard; Selina Anaya; Mark S Johnson; Kylie J Watts
Journal:  Biochemistry       Date:  2021-08-12       Impact factor: 3.321

9.  Deciphering the Che2 chemosensory pathway and the roles of individual Che2 proteins from Pseudomonas aeruginosa.

Authors:  Emilie Orillard; Kylie J Watts
Journal:  Mol Microbiol       Date:  2020-10-16       Impact factor: 3.501

10.  The Aer2 receptor from Vibrio cholerae is a dual PAS-heme oxygen sensor.

Authors:  Suzanne E Greer-Phillips; Nattakan Sukomon; Teck Khiang Chua; Mark S Johnson; Brian R Crane; Kylie J Watts
Journal:  Mol Microbiol       Date:  2018-07       Impact factor: 3.979
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.