Literature DB >> 22616704

The future of molecular diagnostics for drug-resistant tuberculosis.

Scott K Heysell1, Eric R Houpt.   

Abstract

The last decade has seen significant advances in tuberculosis diagnostics and drug susceptibility testing (DST). During the same time period the prevalence of drug-resistant tuberculosis has increased and therefore it has become critical to understand DST for medications used to treat multidrug-resistant and extensively drug-resistant tuberculosis. This review describes recent molecular diagnostic advances for DST. Recommendations are provided for clinicians interpreting molecular DST and we describe potential opportunities for the field.

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Year:  2012        PMID: 22616704     DOI: 10.1586/erm.12.25

Source DB:  PubMed          Journal:  Expert Rev Mol Diagn        ISSN: 1473-7159            Impact factor:   5.225


  14 in total

1.  Sensititre MycoTB plate compared to Bactec MGIT 960 for first- and second-line antituberculosis drug susceptibility testing in Tanzania: a call to operationalize MICs.

Authors:  Scott K Heysell; Suporn Pholwat; Stellah G Mpagama; Saumu J Pazia; Happy Kumburu; Norah Ndusilo; Jean Gratz; Eric R Houpt; Gibson S Kibiki
Journal:  Antimicrob Agents Chemother       Date:  2015-08-24       Impact factor: 5.191

2.  Infectious Uveitis.

Authors:  Phoebe Lin
Journal:  Curr Ophthalmol Rep       Date:  2015-06-13

Review 3.  Understanding pharmacokinetics to improve tuberculosis treatment outcome.

Authors:  Jonathan Reynolds; Scott K Heysell
Journal:  Expert Opin Drug Metab Toxicol       Date:  2014-03-06       Impact factor: 4.481

4.  Identification of Mycobacterium species and Mycobacterium tuberculosis complex resistance determinants by use of PCR-electrospray ionization mass spectrometry.

Authors:  Patricia J Simner; Seanne P Buckwalter; James R Uhl; Nancy L Wengenack
Journal:  J Clin Microbiol       Date:  2013-08-14       Impact factor: 5.948

5.  Collaborative Effort for a Centralized Worldwide Tuberculosis Relational Sequencing Data Platform.

Authors:  Angela M Starks; Enrique Avilés; Daniela M Cirillo; Claudia M Denkinger; David L Dolinger; Claudia Emerson; Jim Gallarda; Debra Hanna; Peter S Kim; Richard Liwski; Paolo Miotto; Marco Schito; Matteo Zignol
Journal:  Clin Infect Dis       Date:  2015-10-15       Impact factor: 9.079

Review 6.  The diagnostic accuracy of the GenoType(®) MTBDRsl assay for the detection of resistance to second-line anti-tuberculosis drugs.

Authors:  Grant Theron; Jonny Peter; Marty Richardson; Marinus Barnard; Sarah Donegan; Rob Warren; Karen R Steingart; Keertan Dheda
Journal:  Cochrane Database Syst Rev       Date:  2014-10-29

7.  Whole-genome sequencing for rapid susceptibility testing of M. tuberculosis.

Authors:  Claudio U Köser; Josephine M Bryant; Jennifer Becq; M Estée Török; Matthew J Ellington; Marc A Marti-Renom; Andrew J Carmichael; Julian Parkhill; Geoffrey P Smith; Sharon J Peacock
Journal:  N Engl J Med       Date:  2013-07-18       Impact factor: 91.245

Review 8.  Rapid diagnosis of drug resistance to fluoroquinolones, amikacin, capreomycin, kanamycin and ethambutol using genotype MTBDRsl assay: a meta-analysis.

Authors:  Yan Feng; Sijun Liu; Qungang Wang; Liang Wang; Shaowen Tang; Jianming Wang; Wei Lu
Journal:  PLoS One       Date:  2013-02-01       Impact factor: 3.240

9.  Primary multidrug-resistant Mycobacterium tuberculosis in 2 regions, Eastern Siberia, Russian Federation.

Authors:  Svetlana Zhdanova; Scott K Heysell; Oleg Ogarkov; Galina Boyarinova; Galina Alexeeva; Suporn Pholwat; Elena Zorkaltseva; Eric R Houpt; Eugeniy Savilov
Journal:  Emerg Infect Dis       Date:  2013-10       Impact factor: 6.883

10.  Application of quantitative second-line drug susceptibility testing at a multidrug-resistant tuberculosis hospital in Tanzania.

Authors:  Stellah G Mpagama; Eric R Houpt; Suzanne Stroup; Happiness Kumburu; Jean Gratz; Gibson S Kibiki; Scott K Heysell
Journal:  BMC Infect Dis       Date:  2013-09-14       Impact factor: 3.090

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