Literature DB >> 22607273

Genetic discrimination: international perspectives.

M Otlowski1, S Taylor, Y Bombard.   

Abstract

Genetic discrimination (GD) is a complex, multifaceted ethical, psychosocial, and legal phenomenon. It is defined as the differential treatment of asymptomatic individuals or their relatives on the basis of their real or assumed genetic characteristics. This article presents an overview of GD within the contemporary international context. It describes the concept of GD and its contextual features, reviews research evidence regarding people's experiences of GD and the impact of GD within a range of domains, and provides an overview of legal and policy responses to GD that have emerged globally. We argue that GD is a significant and internationally established phenomenon that requires multilevel responses to ensure social justice and equitable outcomes for all citizens. Future research should monitor GD and its impacts within the community as well as institutions and should evaluate the effectiveness of legislative, policy, community education, and systemic responses.

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Year:  2012        PMID: 22607273     DOI: 10.1146/annurev-genom-090711-163800

Source DB:  PubMed          Journal:  Annu Rev Genomics Hum Genet        ISSN: 1527-8204            Impact factor:   8.929


  38 in total

Review 1.  Global trends on fears and concerns of genetic discrimination: a systematic literature review.

Authors:  Annet Wauters; Ine Van Hoyweghen
Journal:  J Hum Genet       Date:  2016-01-07       Impact factor: 3.172

2.  Genetic discrimination legislation in Canada: moving from rhetoric to real debate.

Authors:  Stuart G Nicholls; Patrick Fafard
Journal:  CMAJ       Date:  2016-02-08       Impact factor: 8.262

3.  Criteria for fairly allocating scarce health-care resources to genetic tests: which matter most?

Authors:  Wolf H Rogowski; Scott D Grosse; Jörg Schmidtke; Georg Marckmann
Journal:  Eur J Hum Genet       Date:  2013-08-07       Impact factor: 4.246

4.  Risks of nutrigenomics and nutrigenetics? What the scientists say.

Authors:  T Hurlimann; V Menuz; J Graham; J Robitaille; M-C Vohl; B Godard
Journal:  Genes Nutr       Date:  2013-11-29       Impact factor: 5.523

5.  The Genetic Non-Discrimination Act: critical for promoting health and science in Canada.

Authors:  Yvonne Bombard; Bev Heim-Myers
Journal:  CMAJ       Date:  2018-05-14       Impact factor: 8.262

Review 6.  Genomic medicine for kidney disease.

Authors:  Emily E Groopman; Hila Milo Rasouly; Ali G Gharavi
Journal:  Nat Rev Nephrol       Date:  2018-01-08       Impact factor: 28.314

7.  Opinions, hopes and concerns regarding pharmacogenomics: a comparison of healthy individuals, heart failure patients and heart transplant recipients.

Authors:  K Lachance; S Korol; E O'Meara; A Ducharme; N Racine; M Liszkowski; J L Rouleau; G B Pelletier; M Carrier; M White; S de Denus
Journal:  Pharmacogenomics J       Date:  2014-07-01       Impact factor: 3.550

8.  Living with a Rare Health Condition: The Influence of a Support Community and Public Stigma on Communication, Stress, and Available Support.

Authors:  Xun Zhu; Rachel A Smith; Roxanne L Parrott
Journal:  J Appl Commun Res       Date:  2017-03-22

9.  Harm, hype and evidence: ELSI research and policy guidance.

Authors:  Timothy Caulfield; Subhashini Chandrasekharan; Yann Joly; Robert Cook-Deegan
Journal:  Genome Med       Date:  2013-03-26       Impact factor: 11.117

10.  Citizens' perspectives on personalized medicine: a qualitative public deliberation study.

Authors:  Yvonne Bombard; Julia Abelson; Dorina Simeonov; Francois-Pierre Gauvin
Journal:  Eur J Hum Genet       Date:  2013-01-23       Impact factor: 4.246

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