Literature DB >> 22585070

Stool transplants: ready for prime time?

Jeffrey S Weissman1, Walter Coyle.   

Abstract

Clostridium difficile infection (CDI) is a leading cause of antibiotic- and healthcare-related diarrhea. Predisposing factors for infection include antimicrobial use, exposure to healthcare settings, inflammatory bowel disease, chemotherapy and advanced age, although CDI is now seen in patients without traditional risk factors. The gut microbiome may hold clues to the pathophysiology of CDI and promoting a 'healthy' microbiome has become a focus for CDI therapy. Stool transplant or fecal microbiota transplantation has been shown to be safe and effective for management of recurrent CDI. We offer a protocol for stool transplantation.

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Year:  2012        PMID： 22585070     DOI： 10.1007/s11894-012-0263-7

Source DB:  PubMed          Journal:  Curr Gastroenterol Rep        ISSN： 1522-8037


  19 in total

1.  Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis.

Authors:  B EISEMAN; W SILEN; G S BASCOM; A J KAUVAR
Journal:  Surgery       Date:  1958-11       Impact factor: 3.982

2.  An epidemic, toxin gene-variant strain of Clostridium difficile.

Authors:  L Clifford McDonald; George E Killgore; Angela Thompson; Robert C Owens; Sophia V Kazakova; Susan P Sambol; Stuart Johnson; Dale N Gerding
Journal:  N Engl J Med       Date:  2005-12-01       Impact factor: 91.245

Review 3.  Treatment of refractory and recurrent Clostridium difficile infection.

Authors:  Christina M Surawicz; Jacob Alexander
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2011-04-19       Impact factor: 46.802

Review 4.  The growing incidence and severity of Clostridium difficile infection in inpatient and outpatient settings.

Authors:  Sahil Khanna; Darrell S Pardi
Journal:  Expert Rev Gastroenterol Hepatol       Date:  2010-08       Impact factor: 3.869

5.  Morbidity, mortality, and healthcare burden of nosocomial Clostridium difficile-associated diarrhea in Canadian hospitals.

Authors:  Mark A Miller; Meagan Hyland; Marianna Ofner-Agostini; Marie Gourdeau; Magued Ishak
Journal:  Infect Control Hosp Epidemiol       Date:  2002-03       Impact factor: 3.254

6.  Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium difficile infection.

Authors:  Matthew J Hamilton; Alexa R Weingarden; Michael J Sadowsky; Alexander Khoruts
Journal:  Am J Gastroenterol       Date:  2012-01-31       Impact factor: 10.864

7.  Fecal transplantation, through colonoscopy, is effective therapy for recurrent Clostridium difficile infection.

Authors:  Eero Mattila; Raija Uusitalo-Seppälä; Maarit Wuorela; Laura Lehtola; Heimo Nurmi; Matti Ristikankare; Veikko Moilanen; Kimmo Salminen; Maaria Seppälä; Petri S Mattila; Veli-Jukka Anttila; Perttu Arkkila
Journal:  Gastroenterology       Date:  2011-12-07       Impact factor: 22.682

8.  Fecal microbiota transplantation for relapsing Clostridium difficile infection in 26 patients: methodology and results.

Authors:  Colleen R Kelly; Lauren de Leon; Niren Jasutkar
Journal:  J Clin Gastroenterol       Date:  2012-02       Impact factor: 3.062

9.  Enterotypes of the human gut microbiome.

Authors:  Manimozhiyan Arumugam; Jeroen Raes; Eric Pelletier; Denis Le Paslier; Takuji Yamada; Daniel R Mende; Gabriel R Fernandes; Julien Tap; Thomas Bruls; Jean-Michel Batto; Marcelo Bertalan; Natalia Borruel; Francesc Casellas; Leyden Fernandez; Laurent Gautier; Torben Hansen; Masahira Hattori; Tetsuya Hayashi; Michiel Kleerebezem; Ken Kurokawa; Marion Leclerc; Florence Levenez; Chaysavanh Manichanh; H Bjørn Nielsen; Trine Nielsen; Nicolas Pons; Julie Poulain; Junjie Qin; Thomas Sicheritz-Ponten; Sebastian Tims; David Torrents; Edgardo Ugarte; Erwin G Zoetendal; Jun Wang; Francisco Guarner; Oluf Pedersen; Willem M de Vos; Søren Brunak; Joel Doré; María Antolín; François Artiguenave; Hervé M Blottiere; Mathieu Almeida; Christian Brechot; Carlos Cara; Christian Chervaux; Antonella Cultrone; Christine Delorme; Gérard Denariaz; Rozenn Dervyn; Konrad U Foerstner; Carsten Friss; Maarten van de Guchte; Eric Guedon; Florence Haimet; Wolfgang Huber; Johan van Hylckama-Vlieg; Alexandre Jamet; Catherine Juste; Ghalia Kaci; Jan Knol; Omar Lakhdari; Severine Layec; Karine Le Roux; Emmanuelle Maguin; Alexandre Mérieux; Raquel Melo Minardi; Christine M'rini; Jean Muller; Raish Oozeer; Julian Parkhill; Pierre Renault; Maria Rescigno; Nicolas Sanchez; Shinichi Sunagawa; Antonio Torrejon; Keith Turner; Gaetana Vandemeulebrouck; Encarna Varela; Yohanan Winogradsky; Georg Zeller; Jean Weissenbach; S Dusko Ehrlich; Peer Bork
Journal:  Nature       Date:  2011-04-20       Impact factor: 49.962

10.  The emerging infectious challenge of clostridium difficile-associated disease in Massachusetts hospitals: clinical and economic consequences.

Authors:  Judith A O'Brien; Betsy J Lahue; J Jaime Caro; David M Davidson
Journal:  Infect Control Hosp Epidemiol       Date:  2007-10-03       Impact factor: 3.254
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  3 in total

1.  Fecal transplantation therapy for Clostridium difficile-associated pouchitis.

Authors:  Lisa N Patel; Jason Schairer; Bo Shen
Journal:  Int J Colorectal Dis       Date:  2013-10-17       Impact factor: 2.571

Review 2.  Inflammation and colorectal cancer: colitis-associated neoplasia.

Authors:  Sergei I Grivennikov
Journal:  Semin Immunopathol       Date:  2012-11-16       Impact factor: 9.623

3.  Current status of surgical treatment for fulminant clostridium difficile colitis.

Authors:  Andrew J Klobuka; Alexey Markelov
Journal:  World J Gastrointest Surg       Date:  2013-06-27
  3 in total

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