Literature DB >> 22576046

Phosphatases in SMAD regulation.

David L Bruce1, Gopal P Sapkota.   

Abstract

SMAD transcription factors are key mediators of the transforming growth factor-beta (TGFß) family of cytokines. Reversible phosphorylation of SMAD proteins plays a key role in regulating their function. Several phosphatases have been proposed to act on SMAD proteins to influence TGFß/BMP signalling. Here we provide an overview of the SMAD regulation by different protein phosphatases and review the evidence supporting each phosphatase as a candidate SMAD-phosphatase.
Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

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Year:  2012        PMID： 22576046     DOI： 10.1016/j.febslet.2012.02.001

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  33 in total

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Authors:  Theresa M Filtz; Walter K Vogel; Mark Leid
Journal:  Trends Pharmacol Sci       Date:  2013-12-30       Impact factor: 14.819

2.  Ubiquitin removal in the TGF-β pathway.

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Journal:  Nat Cell Biol       Date:  2012-06-29       Impact factor: 28.824

3.  FAD104, a regulatory factor of adipogenesis, acts as a novel regulator of calvarial bone formation.

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Journal:  J Biol Chem       Date:  2013-09-19       Impact factor: 5.157

Review 4.  TGFβ signalling in context.

Authors:  Joan Massagué
Journal:  Nat Rev Mol Cell Biol       Date:  2012-09-20       Impact factor: 94.444

Review 5.  TGFβ/BMP Signaling Pathway in Cartilage Homeostasis.

Authors:  Nathalie G M Thielen; Peter M van der Kraan; Arjan P M van Caam
Journal:  Cells       Date:  2019-08-24       Impact factor: 6.600

Review 6.  Beyond TGFβ: roles of other TGFβ superfamily members in cancer.

Authors:  Lalage M Wakefield; Caroline S Hill
Journal:  Nat Rev Cancer       Date:  2013-05       Impact factor: 60.716

7.  High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds.

Authors:  Shayna T J Bradford; Egon J Ranghini; Edward Grimley; Pil H Lee; Gregory R Dressler
Journal:  J Biol Chem       Date:  2019-01-02       Impact factor: 5.157

Review 8.  Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease.

Authors:  Yael Aschner; Gregory P Downey
Journal:  Am J Respir Cell Mol Biol       Date:  2016-05       Impact factor: 6.914

9.  Expression of bone morphogenetic protein 2, 4, and related components of the BMP signaling pathway in the mouse uterus during the estrous cycle.

Authors:  Yan Li; Quan-wei Wei; Jian-gang Feng; Mu-lin Xu; Rui-hua Huang; Fang-xiong Shi
Journal:  J Zhejiang Univ Sci B       Date:  2014-07       Impact factor: 3.066

10.  Calcineurin signaling regulates neural induction through antagonizing the BMP pathway.

Authors:  Yitai Tang; Jonathan Davila; Ahryon Cho; Suhua Deng; Lei Chen; Erik Miller; Marius Wernig; Isabella A Graef
Journal:  Neuron       Date:  2014-04-02       Impact factor: 17.173
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