Literature DB >> 22564520

Metastatic disease of the long bones: a review of the health care burden in a major trauma centre.

Michael Kelly1, Mitchell Lee, Paul Clarkson, Peter J O'Brien.   

Abstract

BACKGROUND: More than 140,000 new cases of cancer are diagnosed annually in Canada, nearly half of which metastasize to bone. The implications for orthopedic oncology services are potentially huge. We reviewed the experience in a major Canadian orthopedic trauma centre treating long bone metastases. The primary aim was to quantify the caseload, and the secondary aim was to report on the methods of fixation.
METHODS: We conducted a retrospective review of all patients treated for pathologic lesions or fracture secondary to metastatic disease over a 20-year period from July 1987 to March 2007.
RESULTS: The mean number of cases treated annually was 13. Most patients came from the local oncology centre. The median length of stay in hospital was 11 days. In-hospital mortality was 14%. The fatal pulmonary embolus rate was 5% for femoral lesions. The revision rate for the operative intervention was 3%.
CONCLUSION: The caseload was much lower than anticipated, likely owing to under-referring from oncology services. The high mortality rate may reflect delay in seeking orthopedic opinion, but overall the fixation methods appeared durable.

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Mesh:

Year:  2012        PMID: 22564520      PMCID: PMC3310763          DOI: 10.1503/cjs.049009

Source DB:  PubMed          Journal:  Can J Surg        ISSN: 0008-428X            Impact factor:   2.089


  9 in total

1.  Surgical treatment of skeletal metastatic lesions of the proximal femur: endoprosthesis or reconstruction nail?

Authors:  R Wedin; H C F Bauer
Journal:  J Bone Joint Surg Br       Date:  2005-12

Review 2.  Managing skeletal related events resulting from bone metastases.

Authors:  Anna N Wilkinson; Raymond Viola; Michael D Brundage
Journal:  BMJ       Date:  2008-11-03

3.  Failures after operation for skeletal metastatic lesions of long bones.

Authors:  R Wedin; H C Bauer; P Wersäll
Journal:  Clin Orthop Relat Res       Date:  1999-01       Impact factor: 4.176

4.  Solitary bony metastasis from renal cell carcinoma: significance of surgical treatment.

Authors:  Bruno Fuchs; Robert T Trousdale; Michael G Rock
Journal:  Clin Orthop Relat Res       Date:  2005-02       Impact factor: 4.176

Review 5.  Complications of bone metastases: surgical management.

Authors:  J H Healey; H K Brown
Journal:  Cancer       Date:  2000-06-15       Impact factor: 6.860

6.  Metastatic bone disease. A study of the surgical treatment of 166 pathologic humeral and femoral fractures.

Authors:  Y Yazawa; F J Frassica; E Y Chao; D J Pritchard; F H Sim; T C Shives
Journal:  Clin Orthop Relat Res       Date:  1990-02       Impact factor: 4.176

Review 7.  Management of pathologic fractures of the proximal femur: state of the art.

Authors:  David J Jacofsky; George J Haidukewych
Journal:  J Orthop Trauma       Date:  2004-08       Impact factor: 2.512

8.  Endoprosthetic reconstructions for bone metastases.

Authors:  Jeffrey J Eckardt; J Michael Kabo; Cynthia M Kelly; William G Ward; Christopher P Cannon
Journal:  Clin Orthop Relat Res       Date:  2003-10       Impact factor: 4.176

9.  The use of massive endoprostheses for the treatment of bone metastases.

Authors:  D H Park; P K Jaiswal; W Al-Hakim; W J S Aston; R C Pollock; J A Skinner; S R Cannon; T W R Briggs
Journal:  Sarcoma       Date:  2007
  9 in total
  6 in total

1.  Physician preferences for bone metastasis drug therapy in Canada.

Authors:  J Arellano; J M González; Y Qian; M Habib; A F Mohamed; F Gatta; A B Hauber; J Posner; N Califaretti; E Chow
Journal:  Curr Oncol       Date:  2015-10       Impact factor: 3.677

2.  The Influence of Hospital Characteristics on Patient Survival in Surgically Managed Metastatic Disease of Bone: An Analysis of the SEER-Medicare Linked Database.

Authors:  Emma L Herbach; Bradley D McDowell; Elizabeth A Chrischilles; Benjamin J Miller
Journal:  Am J Clin Oncol       Date:  2022-07-06       Impact factor: 2.787

3.  Treatment of Metastasis in the Appendicular Skeleton.

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Journal:  Rev Bras Ortop (Sao Paulo)       Date:  2022-05-27

4.  The burden of metastatic disease of the femur on the Medicare system.

Authors:  Kirollos Gendi; David Hennessy; John Heiner
Journal:  Springerplus       Date:  2016-11-04

Review 5.  Percutaneous consolidation of bone metastases: strategies and techniques.

Authors:  Roberto Luigi Cazzato; Julien Garnon; Benham Shaygi; Emanuele Boatta; Guillaume Koch; Jean Palussiere; Xavier Buy; Afshin Gangi
Journal:  Insights Imaging       Date:  2019-02-06

6.  Biomechanical effects of osteoplasty with or without Kirschner wire augmentation on long bone diaphyses undergoing bending stress: implications for percutaneous imaging-guided consolidation in cancer patients.

Authors:  Roberto Luigi Cazzato; Guillaume Koch; Julien Garnon; Nitin Ramamurthy; Jérémie Jégu; Philippe Clavert; Afshin Gangi
Journal:  Eur Radiol Exp       Date:  2019-01-28
  6 in total

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