Literature DB >> 22555385

HIV-exposed uninfected infants are at increased risk for severe infections in the first year of life.

Amy Slogrove1, Brian Reikie, Shalena Naidoo, Corena De Beer, Kevin Ho, Mark Cotton, Julie Bettinger, David Speert, Monika Esser, Tobias Kollmann.   

Abstract

HIV-exposed uninfected (HEU) infants have higher infectious morbidity than HIV-unexposed uninfected (HUU) infants. We present the clinical outcomes from a pilot cohort study of 27 HEU and 28 HUU infants. In the absence of infant malnutrition or advanced maternal HIV, HEU infants experienced a 2.74 (0.85-8.78) times greater risk of hospitalization in the first year.

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Year:  2012        PMID： 22555385      PMCID： PMC3612013          DOI： 10.1093/tropej/fms019

Source DB:  PubMed          Journal:  J Trop Pediatr        ISSN： 0142-6338            Impact factor:   1.165


  8 in total

1.  Effect of perinatal antiretroviral drug exposure on hematologic values in HIV-uninfected children: An analysis of the women and infants transmission study.

Authors:  Susan E Pacheco; Kenneth McIntosh; Ming Lu; Lynne M Mofenson; Clemente Diaz; Marc Foca; Margaret Frederick; Edward Handelsman; Karen Hayani; William T Shearer
Journal:  J Infect Dis       Date:  2006-09-11       Impact factor: 5.226

2.  Morbidity among human immunodeficiency virus-exposed but uninfected, human immunodeficiency virus-infected, and human immunodeficiency virus-unexposed infants in Zimbabwe before availability of highly active antiretroviral therapy.

Authors:  Ai Koyanagi; Jean H Humphrey; Robert Ntozini; Kusum Nathoo; Lawrence H Moulton; Peter Iliff; Kuda Mutasa; Andrea Ruff; Brian Ward
Journal:  Pediatr Infect Dis J       Date:  2011-01       Impact factor: 2.129

3.  Effect of breastfeeding on infant and child mortality due to infectious diseases in less developed countries: a pooled analysis. WHO Collaborative Study Team on the Role of Breastfeeding on the Prevention of Infant Mortality.

Authors: 
Journal:  Lancet       Date:  2000-02-05       Impact factor: 79.321

4.  Does severity of HIV disease in HIV-infected mothers affect mortality and morbidity among their uninfected infants?

Authors:  Louise Kuhn; Prisca Kasonde; Moses Sinkala; Chipepo Kankasa; Katherine Semrau; Nancy Scott; Wei-Yann Tsai; Sten H Vermund; Grace M Aldrovandi; Donald M Thea
Journal:  Clin Infect Dis       Date:  2005-10-27       Impact factor: 9.079

5.  Early weaning of HIV-exposed uninfected infants and risk of serious gastroenteritis: Findings from two perinatal HIV prevention trials in Kampala, Uganda.

Authors:  Carolyne Onyango-Makumbi; Danstan Bagenda; Antony Mwatha; Saad B Omer; Philippa Musoke; Francis Mmiro; Sheryl L Zwerski; Brenda Asiimwe Kateera; Maria Musisi; Mary Glenn Fowler; J Brooks Jackson; Laura A Guay
Journal:  J Acquir Immune Defic Syndr       Date:  2010-01       Impact factor: 3.731

6.  Frequency of gastroenteritis and gastroenteritis-associated mortality with early weaning in HIV-1-uninfected children born to HIV-infected women in Malawi.

Authors:  George Kafulafula; Donald R Hoover; Taha E Taha; Michael Thigpen; Qing Li; Mary Glenn Fowler; Newton I Kumwenda; Kondwani Nkanaunena; Linda Mipando; Lynne M Mofenson
Journal:  J Acquir Immune Defic Syndr       Date:  2010-01       Impact factor: 3.731

7.  Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis.

Authors:  Marie-Louise Newell; Hoosen Coovadia; Marjo Cortina-Borja; Nigel Rollins; Philippe Gaillard; Francois Dabis
Journal:  Lancet       Date:  2004 Oct 2-8       Impact factor: 79.321

8.  Child mortality according to maternal and infant HIV status in Zimbabwe.

Authors:  Edmore Marinda; Jean H Humphrey; Peter J Iliff; Kuda Mutasa; Kusum J Nathoo; Ellen G Piwoz; Lawrence H Moulton; Peter Salama; Brian J Ward
Journal:  Pediatr Infect Dis J       Date:  2007-06       Impact factor: 2.129
  8 in total
  66 in total

1.  Factors Associated with Lower Respiratory Tract Infections in HIV-Exposed Uninfected Infants.

Authors:  Adriana Weinberg; Marisa M Mussi-Pinhata; Qilu Yu; Rachel A Cohen; Volia C Almeida; Fabiana R Amaral; Laura Freimanis; Donald Robert Harris; Christiana Smith; George Siberry
Journal:  AIDS Res Hum Retroviruses       Date:  2018-04-23       Impact factor: 2.205

Review 2.  Impact of maternal HIV exposure, feeding status, and microbiome on infant cellular immunity.

Authors:  Sonwabile Dzanibe; Heather B Jaspan; Michael Z Zulu; Agano Kiravu; Clive M Gray
Journal:  J Leukoc Biol       Date:  2018-12-21       Impact factor: 4.962

3.  Considerations in evaluating infectious morbidity and mortality in HIV-exposed uninfected infants.

Authors:  Amy L Slogrove; Kathleen M Powis; Julie A Bettinger; Mark F Cotton
Journal:  AIDS       Date:  2018-11-28       Impact factor: 4.177

4.  High-risk enteric pathogens associated with HIV infection and HIV exposure in Kenyan children with acute diarrhoea.

Authors:  Patricia B Pavlinac; Grace C John-Stewart; Jaqueline M Naulikha; Frankline M Onchiri; Donna M Denno; Elizabeth A Odundo; Benson O Singa; Barbra A Richardson; Judd L Walson
Journal:  AIDS       Date:  2014-09-24       Impact factor: 4.177

Review 5.  The Immune System of HIV-Exposed Uninfected Infants.

Authors:  Bahaa Abu-Raya; Tobias R Kollmann; Arnaud Marchant; Duncan M MacGillivray
Journal:  Front Immunol       Date:  2016-09-28       Impact factor: 7.561

6.  Words-in-Noise Test Performance in Young Adults Perinatally HIV Infected and Exposed, Uninfected.

Authors:  Peter Torre; Jonathan S Russell; Renee Smith; Howard J Hoffman; Sonia Lee; Paige L Williams; Tzy-Jyun Yao
Journal:  Am J Audiol       Date:  2020-01-31       Impact factor: 1.493

7.  High Burden of Morbidity and Mortality but Not Growth Failure in Infants Exposed to but Uninfected with Human Immunodeficiency Virus in Tanzania.

Authors:  Lindsey M Locks; Karim P Manji; Roland Kupka; Enju Liu; Rodrick Kisenge; Christine M McDonald; Said Aboud; Molin Wang; Wafaie W Fawzi; Christopher P Duggan
Journal:  J Pediatr       Date:  2016-11-07       Impact factor: 4.406

Review 8.  HIV-exposed uninfected children: a growing population with a vulnerable immune system?

Authors:  L Afran; M Garcia Knight; E Nduati; B C Urban; R S Heyderman; S L Rowland-Jones
Journal:  Clin Exp Immunol       Date:  2014-04       Impact factor: 4.330

9.  Infectious Morbidity, Mortality and Nutrition in HIV-exposed, Uninfected, Formula-fed Infants: Results From the HPTN 040/PACTG 1043 Trial.

Authors:  Nava Yeganeh; D Heather Watts; Jiahong Xu; Tara Kerin; Esau C Joao; Jose Henrique Pilotto; Gerhard Theron; Glenda Gray; Breno Santos; Rosana Fonseca; Regis Kreitchmann; Jorge Pinto; Marisa M Mussi-Pinhata; Valdilea Veloso; Margaret Camarca; Lynne Mofenson; Jack Moye; Karin Nielsen-Saines
Journal:  Pediatr Infect Dis J       Date:  2018-12       Impact factor: 2.129

10.  Maternal HIV infection influences the microbiome of HIV-uninfected infants.

Authors:  Jeffrey M Bender; Fan Li; Shoria Martelly; Erin Byrt; Vanessa Rouzier; Marguerite Leo; Nicole Tobin; Pia S Pannaraj; Helty Adisetiyo; Adrienne Rollie; Chintda Santiskulvong; Shaun Wang; Chloe Autran; Lars Bode; Daniel Fitzgerald; Louise Kuhn; Grace M Aldrovandi
Journal:  Sci Transl Med       Date:  2016-07-27       Impact factor: 17.956
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