PURPOSE: To assess whether continuous veno-venous hemofiltration (CVVH) with high blood pump flow alters the measurements of cardiac index (CI), global end-diastolic volume indexed (GEDVI), and extravascular lung water indexed (EVLWI) performed by transpulmonary thermodilution. METHODS: Sixty-nine patients were included if they were monitored by a PiCCO2 device and received CVVH through a femoral (n = 62) or an internal jugular (n = 7) dialysis catheter. The blood pump flow was set at 250 mL/min (n = 31) or 350 mL/min (n = 38) and the filtration flow at 6,000 mL/h. A first set of data was collected with a first transpulmonary thermodilution (TD(on)). The blood pump was stopped and the continuous CI derived from pulse contour analysis was recorded (PC(off)). A second data set (TD(off)) was collected before and a last one (TD(on-last)) after restarting the blood pump. RESULTS: [Formula: see text], [Formula: see text], [Formula: see text] , and [Formula: see text] were not significantly different in patients with a femoral dialysis catheter (3.49 ± 0.96, 3.51 ± 0.96, 3.51 ± 0.99, and 3.44 ± 1.00 L min(-1) m(-2), respectively). This was observed with a blood pump flow at 350 mL/min and at 250 mL/min. In these patients with a femoral dialysis catheter, GEDVI did not significantly change when the blood pump was stopped. EVLWI significantly decreased when the blood pump was stopped but to a non-clinically relevant extent (-0.3 ± 0.8 mL/kg). No significant changes in CI, GEDVI, and EVLWI were observed in patients with an internal jugular dialysis catheter over the study period. CONCLUSIONS: CVVH with a high blood flow pump does not alter the transpulmonary thermodilution measurements of CI, GEDVI, and EVLWI.
PURPOSE: To assess whether continuous veno-venous hemofiltration (CVVH) with high blood pump flow alters the measurements of cardiac index (CI), global end-diastolic volume indexed (GEDVI), and extravascular lung water indexed (EVLWI) performed by transpulmonary thermodilution. METHODS: Sixty-nine patients were included if they were monitored by a PiCCO2 device and received CVVH through a femoral (n = 62) or an internal jugular (n = 7) dialysis catheter. The blood pump flow was set at 250 mL/min (n = 31) or 350 mL/min (n = 38) and the filtration flow at 6,000 mL/h. A first set of data was collected with a first transpulmonary thermodilution (TD(on)). The blood pump was stopped and the continuous CI derived from pulse contour analysis was recorded (PC(off)). A second data set (TD(off)) was collected before and a last one (TD(on-last)) after restarting the blood pump. RESULTS: [Formula: see text], [Formula: see text], [Formula: see text] , and [Formula: see text] were not significantly different in patients with a femoral dialysis catheter (3.49 ± 0.96, 3.51 ± 0.96, 3.51 ± 0.99, and 3.44 ± 1.00 L min(-1) m(-2), respectively). This was observed with a blood pump flow at 350 mL/min and at 250 mL/min. In these patients with a femoral dialysis catheter, GEDVI did not significantly change when the blood pump was stopped. EVLWI significantly decreased when the blood pump was stopped but to a non-clinically relevant extent (-0.3 ± 0.8 mL/kg). No significant changes in CI, GEDVI, and EVLWI were observed in patients with an internal jugular dialysis catheter over the study period. CONCLUSIONS: CVVH with a high blood flow pump does not alter the transpulmonary thermodilution measurements of CI, GEDVI, and EVLWI.
Authors: Daniel A Reuter; Cecil Huang; Thomas Edrich; Stanton K Shernan; Holger K Eltzschig Journal: Anesth Analg Date: 2010-03-01 Impact factor: 5.108
Authors: M Haller; C Zöllner; W Manert; J Briegel; E Kilger; J Polasek; T Hummel; H Forst; K Peter Journal: Am J Respir Crit Care Med Date: 1995-12 Impact factor: 21.405
Authors: Wolfgang Huber; Stephan Fuchs; Andreas Minning; Claudius Küchle; Marlena Braun; Analena Beitz; Caroline Schultheiss; Sebastian Mair; Veit Phillip; Sebastian Schmid; Roland M Schmid; Tobias Lahmer Journal: PLoS One Date: 2016-04-18 Impact factor: 3.240