Literature DB >> 22517336

Nasopharyngeal lactate dehydrogenase concentrations predict bronchiolitis severity in a prospective multicenter emergency department study.

Jonathan M Mansbach1, Pedro A Piedra, Federico R Laham, Alexander J McAdam, Sunday Clark, Ashley F Sullivan, Carlos A Camargo.   

Abstract

We reexamined the finding of an inverse relationship between values of nasopharyngeal lactate dehydrogenase, a marker of the innate immune response, and bronchiolitis severity. In a prospective, multicenter study of 258 children, we found in a multivariable model that higher nasopharyngeal lactate dehydrogenase values in young children with bronchiolitis were independently associated with a decreased risk of hospitalization.

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Year:  2012        PMID： 22517336      PMCID： PMC3375381          DOI： 10.1097/INF.0b013e3182565eae

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  10 in total

1.  Decreased innate immune cytokine responses correlate with disease severity in children with respiratory syncytial virus and human rhinovirus bronchiolitis.

Authors:  Carla García; Alejandra Soriano-Fallas; Juanita Lozano; Nora Leos; Ana M Gomez; Octavio Ramilo; Asuncion Mejias
Journal:  Pediatr Infect Dis J       Date:  2012-01       Impact factor: 2.129

2.  Immunopathogenesis of respiratory syncytial virus bronchiolitis.

Authors:  Berkeley L Bennett; Roberto P Garofalo; Stanley G Cron; Yashoda M Hosakote; Robert L Atmar; Charles G Macias; Pedro A Piedra
Journal:  J Infect Dis       Date:  2007-04-12       Impact factor: 5.226

Review 3.  Immune responses and disease enhancement during respiratory syncytial virus infection.

Authors:  Peter J M Openshaw; John S Tregoning
Journal:  Clin Microbiol Rev       Date:  2005-07       Impact factor: 26.132

4.  Effect of practice variation on resource utilization in infants hospitalized for viral lower respiratory illness.

Authors:  D F Willson; S D Horn; J O Hendley; R Smout; J Gassaway
Journal:  Pediatrics       Date:  2001-10       Impact factor: 7.124

5.  Prospective multicenter study of bronchiolitis: predicting safe discharges from the emergency department.

Authors:  Jonathan M Mansbach; Sunday Clark; Norman C Christopher; Frank LoVecchio; Sarah Kunz; Uchechi Acholonu; Carlos A Camargo
Journal:  Pediatrics       Date:  2008-04       Impact factor: 7.124

6.  Prospective multicenter bronchiolitis study: predicting intensive care unit admissions.

Authors:  Dorothy Damore; Jonathan M Mansbach; Sunday Clark; Maria Ramundo; Carlos A Camargo
Journal:  Acad Emerg Med       Date:  2008-09-15       Impact factor: 3.451

7.  Differences in admission rates of children with bronchiolitis by pediatric and general emergency departments.

Authors:  David W Johnson; Carol Adair; Rollin Brant; Joanne Holmwood; Ian Mitchell
Journal:  Pediatrics       Date:  2002-10       Impact factor: 7.124

8.  LDH concentration in nasal-wash fluid as a biochemical predictor of bronchiolitis severity.

Authors:  Federico R Laham; Amanda A Trott; Berkeley L Bennett; Claudia A Kozinetz; Alan M Jewell; Roberto P Garofalo; Pedro A Piedra
Journal:  Pediatrics       Date:  2010-01-25       Impact factor: 7.124

9.  Maternal asthma and maternal smoking are associated with increased risk of bronchiolitis during infancy.

Authors:  Kecia N Carroll; Tebeb Gebretsadik; Marie R Griffin; William D Dupont; Edward F Mitchel; Pingsheng Wu; Rachel Enriquez; Tina V Hartert
Journal:  Pediatrics       Date:  2007-06       Impact factor: 7.124

10.  Prospective multicenter study of the viral etiology of bronchiolitis in the emergency department.

Authors:  Jonathan M Mansbach; Alexander J McAdam; Sunday Clark; Paul D Hain; Robert G Flood; Uchechi Acholonu; Carlos A Camargo
Journal:  Acad Emerg Med       Date:  2008-02       Impact factor: 3.451
  10 in total
  3 in total

1.  Lactate dehydrogenase and caspase activity in nasopharyngeal secretions are predictors of bronchiolitis severity.

Authors:  Reena Mehta; Margaret Scheffler; Lorena Tapia; Letisha Aideyan; Kirtida D Patel; Alan M Jewell; Vasanthi Avadhanula; Minghua Mei; Roberto P Garofalo; Pedro A Piedra
Journal:  Influenza Other Respir Viruses       Date:  2014-08-12       Impact factor: 4.380

2.  Prospective observational study in two Dutch hospitals to assess the performance of inflammatory plasma markers to determine disease severity of viral respiratory tract infections in children.

Authors:  Inge M L Ahout; Kim H Brand; Aldert Zomer; Wilhelma H van den Hurk; Geurt Schilders; Marianne L Brouwer; Chris Neeleman; Ronald de Groot; Gerben Ferwerda
Journal:  BMJ Open       Date:  2017-06-30       Impact factor: 2.692

3.  Lactate dehydrogenase as a marker of nasopharyngeal inflammatory injury during viral upper respiratory infection: implications for acute otitis media.

Authors:  Linda C Ede; James O'Brien; Tasnee Chonmaitree; Yimei Han; Janak A Patel
Journal:  Pediatr Res       Date:  2012-11-30       Impact factor: 3.756
  3 in total

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