Literature DB >> 21829141

Decreased innate immune cytokine responses correlate with disease severity in children with respiratory syncytial virus and human rhinovirus bronchiolitis.

Carla García1, Alejandra Soriano-Fallas, Juanita Lozano, Nora Leos, Ana M Gomez, Octavio Ramilo, Asuncion Mejias.   

Abstract

The immunopathogenesis of respiratory syncytial virus (RSV) and human rhinovirus lower respiratory tract infections in children remains to be defined. We measured nasal wash concentrations of 29 cytokines in infants with RSV or human rhinovirus lower respiratory tract infections. Concentrations of interferon-γ in RSV and innate immunity cytokines in both infections inversely correlated with disease severity.

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Year:  2012        PMID： 21829141     DOI： 10.1097/INF.0b013e31822dc8c1

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  43 in total

1.  Infant Viral Respiratory Infection Nasal Immune-Response Patterns and Their Association with Subsequent Childhood Recurrent Wheeze.

Authors:  Kedir N Turi; Jyoti Shankar; Larry J Anderson; Devi Rajan; Kelsey Gaston; Tebeb Gebretsadik; Suman R Das; Cosby Stone; Emma K Larkin; Christian Rosas-Salazar; Steven M Brunwasser; Martin L Moore; R Stokes Peebles; Tina V Hartert
Journal:  Am J Respir Crit Care Med       Date:  2018-10-15       Impact factor: 21.405

Review 2.  Role of Aging and the Immune Response to Respiratory Viral Infections: Potential Implications for COVID-19.

Authors:  Judy Chen; William J Kelley; Daniel R Goldstein
Journal:  J Immunol       Date:  2020-06-03       Impact factor: 5.422

3.  Novel inflammatory markers, clinical risk factors and virus type associated with severe respiratory syncytial virus infection.

Authors:  Christy M Tabarani; Cynthia A Bonville; Manika Suryadevara; Patrick Branigan; Dongliang Wang; Danning Huang; Helene F Rosenberg; Joseph B Domachowske
Journal:  Pediatr Infect Dis J       Date:  2013-12       Impact factor: 2.129

4.  Clinical Disease Severity Scores and Viral Loads in Children With Respiratory Syncytial Virus Infection.

Authors:  Asuncion Mejias; Helena Brenes-Chacon; Cristina Garcia-Mauriño; Melissa Moore-Clingenpeel; Octavio Ramilo
Journal:  Clin Infect Dis       Date:  2021-06-15       Impact factor: 9.079

5.  Respiratory Syncytial Virus Disease Severity Is Associated with Distinct CD8+ T-Cell Profiles.

Authors:  David T Siefker; Luan Vu; Dahui You; Andrew McBride; Ryleigh Taylor; Tamekia L Jones; John DeVincenzo; Stephania A Cormier
Journal:  Am J Respir Crit Care Med       Date:  2020-02-01       Impact factor: 21.405

Review 6.  Infant Immune Response to Respiratory Viral Infections.

Authors:  Santtu Heinonen; Rosa Rodriguez-Fernandez; Alejandro Diaz; Silvia Oliva Rodriguez-Pastor; Octavio Ramilo; Asuncion Mejias
Journal:  Immunol Allergy Clin North Am       Date:  2019-05-15       Impact factor: 3.479

7.  Depletion of alveolar macrophages prolongs survival in response to acute pneumovirus infection.

Authors:  Peter Rigaux; Kristin E Killoran; Zhijun Qiu; Helene F Rosenberg
Journal:  Virology       Date:  2011-11-30       Impact factor: 3.616

8.  Respiratory Syncytial Virus Genotypes, Host Immune Profiles, and Disease Severity in Young Children Hospitalized With Bronchiolitis.

Authors:  Rosa Rodriguez-Fernandez; Lorena I Tapia; Chin-Fen Yang; Juan Pablo Torres; Susana Chavez-Bueno; Carla Garcia; Lisa M Jaramillo; Melissa Moore-Clingenpeel; Hasan S Jafri; Mark E Peeples; Pedro A Piedra; Octavio Ramilo; Asuncion Mejias
Journal:  J Infect Dis       Date:  2017-12-27       Impact factor: 5.226

9.  Nasopharyngeal Microbiota, Host Transcriptome, and Disease Severity in Children with Respiratory Syncytial Virus Infection.

Authors:  Wouter A A de Steenhuijsen Piters; Santtu Heinonen; Raiza Hasrat; Eleonora Bunsow; Bennett Smith; Maria-Carmen Suarez-Arrabal; Damien Chaussabel; Daniel M Cohen; Elisabeth A M Sanders; Octavio Ramilo; Debby Bogaert; Asuncion Mejias
Journal:  Am J Respir Crit Care Med       Date:  2016-11-01       Impact factor: 21.405

10.  Innate immune dysfunction is associated with enhanced disease severity in infants with severe respiratory syncytial virus bronchiolitis.

Authors:  Cesar Mella; M Carmen Suarez-Arrabal; Santiago Lopez; Julie Stephens; Soledad Fernandez; Mark W Hall; Octavio Ramilo; Asuncion Mejias
Journal:  J Infect Dis       Date:  2012-11-29       Impact factor: 5.226
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