Literature DB >> 22492197

Limited V-shaped cement augmentation of the proximal femur to prevent secondary hip fractures.

Ladina Fliri1, An Sermon, Dirk Wähnert, Werner Schmoelz, Michael Blauth, Markus Windolf.   

Abstract

Patients with a femoral fracture due to osteoporosis are at high risk of sustaining a secondary fracture on the contralateral side. A prophylactic mechanical reinforcement of the contralateral side during operation of the initial fracture could be of interest for such patients. This biomechanical in vitro study investigates the potential of a limited V-shaped bone cement augmentation to prevent secondary hip fractures by targeting the areas of the proximal femur with the highest stresses during a fall. Five pairs of human cadaveric proximal femora were tested in a configuration simulating a fall on the greater trochanter. The femoral neck of one specimen of each pair was augmented with 8-14 ml polymethylmethacrylate from the lateral cortex towards inferior and superior, spanning a V-shaped cement pattern. Clinical relevant fractures were generated with a 45 kg mass in controlled free fall. Load-displacement data were recorded and energy to fracture, fracture load, yield load and stiffness were statistically evaluated. Augmented samples absorbed 124% more energy until fracture compared to their controls (p = 0.043). No significant differences were found between the two groups for fracture load (p = 0.5), yield load (p = 0.35) and stiffness (p = 0.5). Biomechanically, a limited V-shaped prophylactic cement augmentation carries potential to prevent secondary hip fractures indicated by increased energy absorption until fracture. Further investigations are necessary to minimize interference with the biology and to maximize the mechanical benefit of prophylactic augmentation.

Entities:  

Keywords:  Secondary hip fracture; cement augmentation; fall simulation; osteoporosis; polymethylmethacrylate; prophylactic

Mesh:

Substances:

Year:  2012        PMID: 22492197     DOI: 10.1177/0885328212443274

Source DB:  PubMed          Journal:  J Biomater Appl        ISSN: 0885-3282            Impact factor:   2.646


  16 in total

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Authors:  Ehsan Basafa; Mehran Armand
Journal:  J Biomech       Date:  2014-05-14       Impact factor: 2.712

Review 2.  Prophylactic augmentation of the osteoporotic proximal femur-mission impossible?

Authors:  Peter Varga; Ladina Hofmann-Fliri; Michael Blauth; Markus Windolf
Journal:  Bonekey Rep       Date:  2016-12-07

3.  Subject-specific planning of femoroplasty: an experimental verification study.

Authors:  Ehsan Basafa; Ryan J Murphy; Yoshito Otake; Michael D Kutzer; Stephen M Belkoff; Simon C Mears; Mehran Armand
Journal:  J Biomech       Date:  2014-11-12       Impact factor: 2.712

Review 4.  [Cement augmentation and bone graft substitutes-Materials and biomechanics].

Authors:  Boyko Gueorguiev; Mark Lenz
Journal:  Unfallchirurgie (Heidelb)       Date:  2022-04-29

5.  Significance of preoperative planning for prophylactic augmentation of osteoporotic hip: A computational modeling study.

Authors:  Amirhossein Farvardin; Ehsan Basafa; Mahsan Bakhtiarinejad; Mehran Armand
Journal:  J Biomech       Date:  2019-07-19       Impact factor: 2.712

6.  A biomechanically-guided planning and execution paradigm for osteoporotic hip augmentation: Experimental evaluation of the biomechanics and temperature-rise.

Authors:  Amirhossein Farvardin; Mahsan Bakhtiarinejad; Ryan J Murphy; Ehsan Basafa; Harpal Khanuja; Juluis K Oni; Mehran Armand
Journal:  Clin Biomech (Bristol, Avon)       Date:  2021-05-29       Impact factor: 2.034

7.  Implant augmentation: adding bone cement to improve the treatment of osteoporotic distal femur fractures: a biomechanical study using human cadaver bones.

Authors:  Dirk Wähnert; Ladina Hofmann-Fliri; R Geoff Richards; Boyko Gueorguiev; Michael J Raschke; Markus Windolf
Journal:  Medicine (Baltimore)       Date:  2014-11       Impact factor: 1.889

8.  Development of an animal fracture model for evaluation of cement augmentation femoroplasty: an in vitro biomechanical study.

Authors:  Qiang Luo; William W Lu; Tak-Wing Lau; Frankie Leung
Journal:  Biores Open Access       Date:  2014-04-01

9.  Discrete particle model for cement infiltration within open-cell structures: Prevention of osteoporotic fracture.

Authors:  Samuel Jesús Ramos-Infante; Amadeo Ten-Esteve; Angel Alberich-Bayarri; María Angeles Pérez
Journal:  PLoS One       Date:  2018-06-13       Impact factor: 3.240

10.  Static bending test after proximal femoral nail (PFN) removal - in vitro analysis.

Authors:  Leonardo Morais Paiva; Sílvio Leite de Macedo Neto; Diogo Ranier de Macedo Souto; George Neri Barros Ferreira; Hélio Ismael da Costa; Anderson Freitas
Journal:  Rev Bras Ortop       Date:  2017-08-30
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