Literature DB >> 22491476

K48-linked ubiquitination and protein degradation regulate 53BP1 recruitment at DNA damage sites.

Frédérick A Mallette1, Stéphane Richard.   

Abstract

Efficient DNA damage sensing and repair is crucial to preserve genomic integrity and failure to detect or repair DNA breaks can cause mutations, contributing to the formation of tumors. One key protein required for mediating DNA repair is the tumor suppressor 53BP1. Recent studies now demonstrate the crucial role of K48-linked ubiquitination and protein degradation for 53BP1 recruitment at sites of DNA damage.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22491476      PMCID： PMC3411168          DOI： 10.1038/cr.2012.58

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  17 in total

1.  Proteasome function is required for DNA damage response and fanconi anemia pathway activation.

Authors:  Céline Jacquemont; Toshiyasu Taniguchi
Journal:  Cancer Res       Date:  2007-08-01       Impact factor: 12.701

2.  Proteasome involvement in the repair of DNA double-strand breaks.

Authors:  Nevan J Krogan; Mandy H Y Lam; Jeffrey Fillingham; Michael-Christopher Keogh; Marinella Gebbia; Joyce Li; Nira Datta; Gerard Cagney; Stephen Buratowski; Andrew Emili; Jack F Greenblatt
Journal:  Mol Cell       Date:  2004-12-22       Impact factor: 17.970

3.  L3MBTL1 recognition of mono- and dimethylated histones.

Authors:  Jinrong Min; Abdellah Allali-Hassani; Nataliya Nady; Chao Qi; Hui Ouyang; Yongsong Liu; Farrell MacKenzie; Masoud Vedadi; Cheryl H Arrowsmith
Journal:  Nat Struct Mol Biol       Date:  2007-11-18       Impact factor: 15.369

4.  RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.

Authors:  Niels Mailand; Simon Bekker-Jensen; Helene Faustrup; Fredrik Melander; Jiri Bartek; Claudia Lukas; Jiri Lukas
Journal:  Cell       Date:  2007-11-20       Impact factor: 41.582

5.  RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.

Authors:  Michael S Y Huen; Robert Grant; Isaac Manke; Kay Minn; Xiaochun Yu; Michael B Yaffe; Junjie Chen
Journal:  Cell       Date:  2007-11-20       Impact factor: 41.582

Review 6.  Regulatory ubiquitylation in response to DNA double-strand breaks.

Authors:  Stephanie Panier; Daniel Durocher
Journal:  DNA Repair (Amst)       Date:  2009-02-18

7.  RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.

Authors:  Carsten Doil; Niels Mailand; Simon Bekker-Jensen; Patrice Menard; Dorthe Helena Larsen; Rainer Pepperkok; Jan Ellenberg; Stephanie Panier; Daniel Durocher; Jiri Bartek; Jiri Lukas; Claudia Lukas
Journal:  Cell       Date:  2009-02-06       Impact factor: 41.582

8.  RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.

Authors:  Frédérick A Mallette; Francesca Mattiroli; Gaofeng Cui; Leah C Young; Michael J Hendzel; Georges Mer; Titia K Sixma; Stéphane Richard
Journal:  EMBO J       Date:  2012-02-28       Impact factor: 11.598

9.  Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase.

Authors:  Nadine K Kolas; J Ross Chapman; Shinichiro Nakada; Jarkko Ylanko; Richard Chahwan; Frédéric D Sweeney; Stephanie Panier; Megan Mendez; Jan Wildenhain; Timothy M Thomson; Laurence Pelletier; Stephen P Jackson; Daniel Durocher
Journal:  Science       Date:  2007-11-15       Impact factor: 47.728

10.  The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.

Authors:  Grant S Stewart; Stephanie Panier; Kelly Townsend; Abdallah K Al-Hakim; Nadine K Kolas; Edward S Miller; Shinichiro Nakada; Jarkko Ylanko; Signe Olivarius; Megan Mendez; Ceri Oldreive; Jan Wildenhain; Andrea Tagliaferro; Laurence Pelletier; Nadine Taubenheim; Anne Durandy; Philip J Byrd; Tatjana Stankovic; A Malcolm R Taylor; Daniel Durocher
Journal:  Cell       Date:  2009-02-06       Impact factor: 41.582
View more
  16 in total

1.  SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication.

Authors:  Yan Liu; Zhenhua Zheng; Bo Shu; Jin Meng; Yuan Zhang; Caishang Zheng; Xianliang Ke; Peng Gong; Qinxue Hu; Hanzhong Wang
Journal:  J Virol       Date:  2016-11-14       Impact factor: 5.103

2.  Carrier-free nanoprodrug for p53-mutated tumor therapy via concurrent delivery of zinc-manganese dual ions and ROS.

Authors:  Jinping Wang; Chang Qu; Xinyue Shao; Guoqiang Song; Jingyu Sun; Donghong Shi; Ran Jia; Hailong An; Hongjun Wang
Journal:  Bioact Mater       Date:  2022-06-18

3.  Per- and polyfluoroalkyl substances, epigenetic age and DNA methylation: a cross-sectional study of firefighters.

Authors:  Jaclyn M Goodrich; Miriam M Calkins; Alberto J Caban-Martinez; Todd Stueckle; Casey Grant; Antonia M Calafat; Amy Nematollahi; Alesia M Jung; Judith M Graber; Timothy Jenkins; Angela L Slitt; Alisa Dewald; Julianne Cook Botelho; Shawn Beitel; Sally Littau; John Gulotta; Darin Wallentine; Jeff Hughes; Charles Popp; Jefferey L Burgess
Journal:  Epigenomics       Date:  2021-10-21       Impact factor: 4.357

4.  CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair.

Authors:  T R Shenoy; G Boysen; M Y Wang; Q Z Xu; W Guo; F M Koh; C Wang; L Z Zhang; Y Wang; V Gil; S Aziz; R Christova; D N Rodrigues; M Crespo; P Rescigno; N Tunariu; R Riisnaes; Z Zafeiriou; P Flohr; W Yuan; E Knight; A Swain; M Ramalho-Santos; D Y Xu; J de Bono; H Wu
Journal:  Ann Oncol       Date:  2017-07-01       Impact factor: 32.976

5.  Regulation of 53BP1 protein stability by RNF8 and RNF168 is important for efficient DNA double-strand break repair.

Authors:  Yiheng Hu; Chao Wang; Kun Huang; Fen Xia; Jeffrey D Parvin; Neelima Mondal
Journal:  PLoS One       Date:  2014-10-22       Impact factor: 3.240

6.  Adenovirus-mediated downregulation of the ubiquitin ligase RNF8 sensitizes bladder cancer to radiotherapy.

Authors:  Mei-Jun Zhao; Yan-Feng Song; Hai-Tao Niu; Ying-Xia Tian; Xu-Guang Yang; Kun Xie; Yu-Hong Jing; De-Gui Wang
Journal:  Oncotarget       Date:  2016-02-23

Review 7.  HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response.

Authors:  Nicholas A Mathieu; Ermela Paparisto; Stephen D Barr; Donald E Spratt
Journal:  Viruses       Date:  2021-06-09       Impact factor: 5.048

8.  Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.

Authors:  Volker Hable; Guido A Drexler; Tino Brüning; Christian Burgdorf; Christoph Greubel; Anja Derer; Judith Seel; Hilmar Strickfaden; Thomas Cremer; Anna A Friedl; Günther Dollinger
Journal:  PLoS One       Date:  2012-07-30       Impact factor: 3.240

Review 9.  The Skp2 Pathway: A Critical Target for Cancer Therapy.

Authors:  Zhen Cai; Asad Moten; Danni Peng; Che-Chia Hsu; Bo-Syong Pan; Rajeshkumar Manne; Hong-Yu Li; Hui-Kuan Lin
Journal:  Semin Cancer Biol       Date:  2020-02-01       Impact factor: 17.012

10.  Long non-coding RNA ANRIL promotes homologous recombination-mediated DNA repair by maintaining ATR protein stability to enhance cancer resistance.

Authors:  Lei Liu; Yuanyuan Chen; Yijuan Huang; Kun Cao; Tingting Liu; Hui Shen; Jianguo Cui; Bailong Li; Jianming Cai; Fu Gao; Yanyong Yang
Journal:  Mol Cancer       Date:  2021-07-05       Impact factor: 27.401
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.