| Literature DB >> 22489277 |
Chris Cleveland, David Liao, Robert Austin.
Abstract
This is a theoretical paper which examines at a game theoretical perspective the dynamics of cooperators and cheater cells under metabolic stress conditions and high spatial heterogeneity. Although the ultimate aim of this work is to understand the dynamics of cancer tumor evolution under stress, we use a simple bacterial model to gain fundamental insights into the progression of resistance to drugs under high competition and stress conditions.Entities:
Year: 2012 PMID: 22489277 PMCID: PMC3321518 DOI: 10.1063/1.3699043
Source DB: PubMed Journal: AIP Adv Impact factor: 1.548