Literature DB >> 22482500

In epigenetic therapy, less is more.

Hui Shen1, Peter W Laird.   

Abstract

How DNA methylation inhibitors exert their anticancer effects in patients is not well understood. In the latest issue of Cancer Cell, Tsai et al. (2012) use low-dose drug treatment to induce persistent attenuation of tumorigenicity by targeting tumor-initiating cells.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22482500     DOI： 10.1016/j.stem.2012.03.012

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  15 in total

1.  DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR.

Authors:  Goran Micevic; Viswanathan Muthusamy; William Damsky; Nicholas Theodosakis; Xiaoni Liu; Katrina Meeth; Emily Wingrove; Manjula Santhanakrishnan; Marcus Bosenberg
Journal:  Cell Rep       Date:  2016-02-25       Impact factor: 9.423

2.  DNA Methylation and Colorectal Cancer.

Authors:  Hassan Ashktorab; Hassan Brim
Journal:  Curr Colorectal Cancer Rep       Date:  2014-12-01

Review 3.  Combining Epigenetic and Immunotherapy to Combat Cancer.

Authors:  Katherine B Chiappinelli; Cynthia A Zahnow; Nita Ahuja; Stephen B Baylin
Journal:  Cancer Res       Date:  2016-03-17       Impact factor: 12.701

4.  DNA methylome profiling identifies novel methylated genes in African American patients with colorectal neoplasia.

Authors:  Hassan Ashktorab; M Daremipouran; Ajay Goel; Sudhir Varma; R Leavitt; Xueguang Sun; Hassan Brim
Journal:  Epigenetics       Date:  2014-01-17       Impact factor: 4.528

Review 5.  Harnessing the potential of epigenetic therapy to target solid tumors.

Authors:  Nita Ahuja; Hariharan Easwaran; Stephen B Baylin
Journal:  J Clin Invest       Date:  2014-01-02       Impact factor: 14.808

Review 6.  Leveraging modeling and simulation to optimize the therapeutic window for epigenetic modifier drugs.

Authors:  Antje-Christine Walz; Arthur J Van De Vyver; Li Yu; Marc R Birtwistle; Nevan J Krogan; Mehdi Bouhaddou
Journal:  Pharmacol Ther       Date:  2022-02-18       Impact factor: 13.400

7.  DNA methyltransferase inhibition restores erythropoietin production in fibrotic murine kidneys.

Authors:  Yu-Ting Chang; Ching-Chin Yang; Szu-Yu Pan; Yu-Hsiang Chou; Fan-Chi Chang; Chun-Fu Lai; Ming-Hsuan Tsai; Huan-Lun Hsu; Ching-Hung Lin; Wen-Chih Chiang; Ming-Shiou Wu; Tzong-Shinn Chu; Yung-Ming Chen; Shuei-Liong Lin
Journal:  J Clin Invest       Date:  2016-01-05       Impact factor: 14.808

8.  Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

Authors:  Reena Shakya; Tamas Gonda; Michael Quante; Martha Salas; Samuel Kim; Jenna Brooks; Steffen Hirsch; Justine Davies; Angelica Cullo; Kenneth Olive; Timothy C Wang; Matthias Szabolcs; Benjamin Tycko; Thomas Ludwig
Journal:  Cancer Res       Date:  2012-11-29       Impact factor: 12.701

Review 9.  Episensitization: Defying Time's Arrow.

Authors:  Bryan T Oronsky; Arnold L Oronsky; Michelle Lybeck; Neil C Oronsky; Jan J Scicinski; Corey Carter; Regina M Day; Jose F Rodriguez Orengo; Maribel Rodriguez-Torres; Gary F Fanger; Tony R Reid
Journal:  Front Oncol       Date:  2015-06-11       Impact factor: 6.244

10.  A reciprocal role of prostate cancer on stromal DNA damage.

Authors:  J Banerjee; R Mishra; X Li; R S Jackson; A Sharma; N A Bhowmick
Journal:  Oncogene       Date:  2013-10-21       Impact factor: 9.867
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