Literature DB >> 22460111

Hedgehog inhibitor gets landmark skin cancer approval, but questions remain for wider potential.

Malini Guha.   

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Year:  2012        PMID： 22460111     DOI： 10.1038/nrd3714

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  16 in total

Review 1.  Proteostasis in the Hedgehog signaling pathway.

Authors:  Aimin Liu
Journal:  Semin Cell Dev Biol       Date:  2018-11-14       Impact factor: 7.727

2.  Expression of Hedgehog ligand and signal transduction components in mutually distinct isocitrate dehydrogenase mutant glioma cells supports a role for paracrine signaling.

Authors:  Sunday A Abiria; Thomas V Williams; Alexander L Munden; Vandana K Grover; Ato Wallace; Christopher J Lundberg; J Gerardo Valadez; Michael K Cooper
Journal:  J Neurooncol       Date:  2014-05-28       Impact factor: 4.130

Review 3.  The hedgehog pathway in nonalcoholic fatty liver disease.

Authors:  Mariana Verdelho Machado; Anna Mae Diehl
Journal:  Crit Rev Biochem Mol Biol       Date:  2018-03-20       Impact factor: 8.250

Review 4.  The Hedgehog signal transduction network.

Authors:  David J Robbins; Dennis Liang Fei; Natalia A Riobo
Journal:  Sci Signal       Date:  2012-10-16       Impact factor: 8.192

5.  Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice.

Authors:  Guanhua Xie; Gamze Karaca; Marzena Swiderska-Syn; Gregory A Michelotti; Leandi Krüger; Yuping Chen; Richard T Premont; Steve S Choi; Anna Mae Diehl
Journal:  Hepatology       Date:  2013-09-30       Impact factor: 17.425

6.  Signaling: Making a leaner Hedgehog.

Authors:  Chih-wei Fan; Rubina Tuladhar; Lawrence Lum
Journal:  Nat Chem Biol       Date:  2013-04       Impact factor: 15.040

7.  Hedgehog inhibition reduces angiogenesis by downregulation of tumoral VEGF-A expression in hepatocellular carcinoma.

Authors:  Matthias Pinter; Wolfgang Sieghart; Monika Schmid; Bernhard Dauser; Gerald Prager; Hans Peter Dienes; Michael Trauner; Markus Peck-Radosavljevic
Journal:  United European Gastroenterol J       Date:  2013-08       Impact factor: 4.623

Review 8.  Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer.

Authors:  Jihoon W Lee; Kajan Ratnakumar; Kai-Feng Hung; Daiki Rokunohe; Masaoki Kawasumi
Journal:  Photochem Photobiol       Date:  2020-05-04       Impact factor: 3.421

9.  Ballooned hepatocytes, undead cells, sonic hedgehog, and vitamin E: therapeutic implications for nonalcoholic steatohepatitis.

Authors:  Petra Hirsova; Gregory J Gores
Journal:  Hepatology       Date:  2014-11-20       Impact factor: 17.425

10.  The dawn of hedgehog inhibitors: Vismodegib.

Authors:  Selvarajan Sandhiya; George Melvin; Srinivasamurthy Suresh Kumar; Steven Aibor Dkhar
Journal:  J Pharmacol Pharmacother       Date:  2013-01
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