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Literature DB >> 24975580

Ballooned hepatocytes, undead cells, sonic hedgehog, and vitamin E: therapeutic implications for nonalcoholic steatohepatitis.

Petra Hirsova¹, Gregory J Gores.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

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Year: 2014 PMID： 24975580 PMCID： PMC4277507 DOI： 10.1002/hep.27279

Source DB: PubMed Journal: Hepatology ISSN： 0270-9139 Impact factor: 17.425

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16 in total

1. Hedgehog inhibitor gets landmark skin cancer approval, but questions remain for wider potential.

Authors: Malini Guha
Journal: Nat Rev Drug Discov Date: 2012-03-30 Impact factor: 84.694

2. A hedgehog survival pathway in 'undead' lipotoxic hepatocytes.

Authors: Keisuke Kakisaka; Sophie C Cazanave; Nathan W Werneburg; Nataliya Razumilava; Joachim C Mertens; Steve F Bronk; Gregory J Gores
Journal: J Hepatol Date: 2012-05-26 Impact factor: 25.083

Review 3. Apoptosis: controlled demolition at the cellular level.

Authors: Rebecca C Taylor; Sean P Cullen; Seamus J Martin
Journal: Nat Rev Mol Cell Biol Date: 2008-03 Impact factor: 94.444

4. Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity.

Authors: Cynthia D Guy; Ayako Suzuki; Manal F Abdelmalek; James L Burchette; Anna Mae Diehl
Journal: Hepatology Date: 2014-08-25 Impact factor: 17.425

5. Design and validation of a histological scoring system for nonalcoholic fatty liver disease.

Authors: David E Kleiner; Elizabeth M Brunt; Mark Van Natta; Cynthia Behling; Melissa J Contos; Oscar W Cummings; Linda D Ferrell; Yao-Chang Liu; Michael S Torbenson; Aynur Unalp-Arida; Matthew Yeh; Arthur J McCullough; Arun J Sanyal
Journal: Hepatology Date: 2005-06 Impact factor: 17.425

6. Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappaB in the liver of nonalcoholic and alcoholic steatohepatitis patients.

Authors: Paulo S Ribeiro; Helena Cortez-Pinto; Susana Solá; Rui E Castro; Rita M Ramalho; Amélia Baptista; Miguel C Moura; Maria E Camilo; Cecília M P Rodrigues
Journal: Am J Gastroenterol Date: 2004-09 Impact factor: 10.864

Review 7. The Hedgehog signal transduction network.

Authors: David J Robbins; Dennis Liang Fei; Natalia A Riobo
Journal: Sci Signal Date: 2012-10-16 Impact factor: 8.192

8. Hedgehog-stimulated chemotaxis is mediated by smoothened located outside the primary cilium.

Authors: Maarten F Bijlsma; Helene Damhofer; Henk Roelink
Journal: Sci Signal Date: 2012-08-21 Impact factor: 8.192

9. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis.

Authors: Ariel E Feldstein; Ali Canbay; Paul Angulo; Makiko Taniai; Lawrence J Burgart; Keith D Lindor; Gregory J Gores
Journal: Gastroenterology Date: 2003-08 Impact factor: 22.682

10. Vismodegib suppresses TRAIL-mediated liver injury in a mouse model of nonalcoholic steatohepatitis.

Authors: Petra Hirsova; Samar H Ibrahim; Steven F Bronk; Hideo Yagita; Gregory J Gores
Journal: PLoS One Date: 2013-07-22 Impact factor: 3.240

15 in total

1. Transcriptional Network Analysis Implicates Altered Hepatic Immune Function in NASH development and resolution.

Authors: Joel T Haas; Luisa Vonghia; Denis A Mogilenko; An Verrijken; Olivier Molendi-Coste; Sébastien Fleury; Audrey Deprince; Artemii Nikitin; Eloïse Woitrain; Lucie Ducrocq-Geoffroy; Samuel Pic; Bruno Derudas; Hélène Dehondt; Céline Gheeraert; Luc Van Gaal; Ann Driessen; Philippe Lefebvre; Bart Staels; Sven Francque; David Dombrowicz
Journal: Nat Metab Date: 2019-06-14

Review 2. Non-alcoholic steatohepatitis pathogenesis: sublethal hepatocyte injury as a driver of liver inflammation.

Authors: Samar H Ibrahim; Petra Hirsova; Gregory J Gores
Journal: Gut Date: 2018-01-24 Impact factor: 23.059

3. Evaluation of ballooned hepatocytes as a risk factor for future progression of fibrosis in patients with non-alcoholic fatty liver disease.

Authors: Keisuke Kakisaka; Yuji Suzuki; Yudai Fujiwara; Tamami Abe; Miki Yonezawa; Hidekatsu Kuroda; Kazuyuki Ishida; Tamotsu Sugai; Yasuhiro Takikawa
Journal: J Gastroenterol Date: 2018-04-21 Impact factor: 7.527

Review 4. Translating scientific discovery: the need for preclinical models of nonalcoholic steatohepatitis.

Authors: Abdul M Oseini; Banumathi K Cole; Danny Issa; Ryan E Feaver; Arun J Sanyal
Journal: Hepatol Int Date: 2018-01-03 Impact factor: 6.047

Review 5. Mechanisms of Fibrosis Development in Nonalcoholic Steatohepatitis.

Authors: Robert F Schwabe; Ira Tabas; Utpal B Pajvani
Journal: Gastroenterology Date: 2020-02-08 Impact factor: 22.682

6. Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease.

Authors: Mariana Verdelho Machado; Gregory Alexander Michelotti; Guanhua Xie; Thiago Almeida Pereira; Thiago Pereira de Almeida; Jerome Boursier; Brittany Bohnic; Cynthia D Guy; Anna Mae Diehl
Journal: PLoS One Date: 2015-05-27 Impact factor: 3.240

7. A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver.

Authors: Miyuki Suzawa; Diego A Miranda; Karmela A Ramos; Kenny K-H Ang; Emily J Faivre; Christopher G Wilson; Laura Caboni; Michelle R Arkin; Yeong-Sang Kim; Robert J Fletterick; Aaron Diaz; John S Schneekloth; Holly A Ingraham
Journal: Elife Date: 2015-12-11 Impact factor: 8.140