Literature DB >> 23508185

Signaling: Making a leaner Hedgehog.

Chih-wei Fan, Rubina Tuladhar, Lawrence Lum.   

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Year:  2013        PMID： 23508185      PMCID： PMC4174596          DOI： 10.1038/nchembio.1209

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  11 in total

1.  A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling.

Authors:  K Hofmann
Journal:  Trends Biochem Sci       Date:  2000-03       Impact factor: 13.807

Review 2.  Novel lipid modifications of secreted protein signals.

Authors:  Randall K Mann; Philip A Beachy
Journal:  Annu Rev Biochem       Date:  2004       Impact factor: 23.643

Review 3.  Wnt signaling signaling at and above the receptor level.

Authors:  Tina Buechling; Michael Boutros
Journal:  Curr Top Dev Biol       Date:  2011       Impact factor: 4.897

4.  Hedgehog inhibitor gets landmark skin cancer approval, but questions remain for wider potential.

Authors:  Malini Guha
Journal:  Nat Rev Drug Discov       Date:  2012-03-30       Impact factor: 84.694

5.  Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor.

Authors:  Brad P Barnett; Yousang Hwang; Martin S Taylor; Henriette Kirchner; Paul T Pfluger; Vincent Bernard; Yu-yi Lin; Erin M Bowers; Chandrani Mukherjee; Woo-Jin Song; Patti A Longo; Daniel J Leahy; Mehboob A Hussain; Matthias H Tschöp; Jef D Boeke; Philip A Cole
Journal:  Science       Date:  2010-11-18       Impact factor: 47.728

Review 6.  Drugging the cancer stem cell compartment: lessons learned from the hedgehog and Wnt signal transduction pathways.

Authors:  Michael E Dodge; Lawrence Lum
Journal:  Annu Rev Pharmacol Toxicol       Date:  2011       Impact factor: 13.820

7.  Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides.

Authors:  Jing Yang; Tong-Jin Zhao; Joseph L Goldstein; Michael S Brown
Journal:  Proc Natl Acad Sci U S A       Date:  2008-07-31       Impact factor: 11.205

Review 8.  Hedgehog signaling in development and cancer.

Authors:  Jin Jiang; Chi-Chung Hui
Journal:  Dev Cell       Date:  2008-12       Impact factor: 12.270

Review 9.  Paracrine Hedgehog signaling in cancer.

Authors:  Jan-Willem Theunissen; Frederic J de Sauvage
Journal:  Cancer Res       Date:  2009-07-28       Impact factor: 12.701

10.  Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling.

Authors:  Elissaveta Petrova; Jessica Rios-Esteves; Ouathek Ouerfelli; J Fraser Glickman; Marilyn D Resh
Journal:  Nat Chem Biol       Date:  2013-02-17       Impact factor: 15.040
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