Literature DB >> 22457316

Troponin-positive chest pain with unobstructed coronary arteries: definitive differential diagnosis using cardiac MRI.

M Mahmoudi1, S Harden, N Abid, C Peebles, Z Nicholas, T Jones, D McKenzie, N Curzen.   

Abstract

OBJECTIVE: The purpose of this study was to assess the outcome of cardiac MRI (CMRI) with late gadolinium enhancement (LGE) at outpatient follow-up in a consecutive series of patients with troponin-positive chest pain but unobstructed coronary arteries at the index admission.
METHODS: The study group comprised 91 consecutive patients who presented to our institution with cardiac chest pain, elevated troponin I and unobstructed coronary arteries on coronary angiography. All patients underwent an outpatient CMRI with LGE imaging in order to establish a definitive diagnosis.
RESULTS: The average time from coronary angiography to LGE-CMRI was 2 months. 73% of patients had no abnormality on their LGE-CMRI, 16% of patients had patchy late enhancement consistent with myocarditis and 11% had focal subendocardial or full thickness late enhancement consistent with myocardial infarction. There were no deaths in this cohort during a mean follow-up of 21 months.
CONCLUSION: LGE-CMRI is a useful tool for establishing whether such patients have definitive evidence of non-ST-segment elevation myocardial infarction (NSTEMI), and can make an important contribution to the long-term management strategy of these patients as an inappropriate diagnosis of NSTEMI carries important medical, social and financial implications.

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Year:  2012        PMID: 22457316      PMCID: PMC3587061          DOI: 10.1259/bjr/90663866

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  18 in total

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3.  ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non ST-Elevation Myocardial Infarction): developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine.

Authors:  Jeffrey L Anderson; Cynthia D Adams; Elliott M Antman; Charles R Bridges; Robert M Califf; Donald E Casey; William E Chavey; Francis M Fesmire; Judith S Hochman; Thomas N Levin; A Michael Lincoff; Eric D Peterson; Pierre Theroux; Nanette Kass Wenger; R Scott Wright; Sidney C Smith; Alice K Jacobs; Jonathan L Halperin; Sharon A Hunt; Harlan M Krumholz; Frederick G Kushner; Bruce W Lytle; Rick Nishimura; Joseph P Ornato; Richard L Page; Barbara Riegel
Journal:  Circulation       Date:  2007-08-06       Impact factor: 29.690

4.  Troponin-positive chest pain with unobstructed coronary arteries: a role for delayed enhanced cardiovascular magnetic resonance in the diagnosis of non-ST elevation myocardial infarction.

Authors:  Nick G Bellenger; Charles Peebles; Stephen Harden; Keith Dawkins; Nick Curzen
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5.  The role of cardiovascular magnetic resonance in patients presenting with chest pain, raised troponin, and unobstructed coronary arteries.

Authors:  Ravi G Assomull; Jonathan C Lyne; Niall Keenan; Ankur Gulati; Nicholas H Bunce; Simon W Davies; Dudley J Pennell; Sanjay K Prasad
Journal:  Eur Heart J       Date:  2007-05-03       Impact factor: 29.983

6.  Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes.

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Authors:  C P Cannon; W S Weintraub; L A Demopoulos; R Vicari; M J Frey; N Lakkis; F J Neumann; D H Robertson; P T DeLucca; P M DiBattiste; C M Gibson; E Braunwald
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  9 in total

1.  The incremental impact of cardiac MRI on clinical decision-making.

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Journal:  Br J Radiol       Date:  2015-10-23       Impact factor: 3.039

Review 2.  The Role of Cardiac MRI in Patients with Troponin-Positive Chest Pain and Unobstructed Coronary Arteries.

Authors:  Amardeep Ghosh Dastidar; Jonathan C L Rodrigues; Nauman Ahmed; Anna Baritussio; Chiara Bucciarelli-Ducci
Journal:  Curr Cardiovasc Imaging Rep       Date:  2015

3.  The unique value of cardiovascular magnetic resonance in patients with suspected acute coronary syndrome and culprit-free coronary angiograms.

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Journal:  BMC Cardiovasc Disord       Date:  2017-06-28       Impact factor: 2.298

4.  Early cardiac magnetic resonance imaging in troponin-positive acute chest pain and non-obstructed coronary arteries.

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Journal:  Heart       Date:  2020-05-23       Impact factor: 5.994

Review 5.  Epidemiological Impact of Myocarditis.

Authors:  Ainoosh Golpour; Dimitri Patriki; Paul J Hanson; Bruce McManus; Bettina Heidecker
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6.  Imaging diagnoses and outcome in patients presenting for primary angioplasty but no obstructive coronary artery disease.

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Journal:  Heart       Date:  2016-07-01       Impact factor: 5.994

Review 7.  Guidelines for the management of myocardial infarction/injury with non-obstructive coronary arteries (MINOCA): a position paper from the Dutch ACS working group.

Authors:  T F S Pustjens; Y Appelman; P Damman; J M Ten Berg; J W Jukema; R J de Winter; W R P Agema; M L J van der Wielen; F Arslan; S Rasoul; A W J van 't Hof
Journal:  Neth Heart J       Date:  2020-03       Impact factor: 2.380

Review 8.  Troponin-Positive Non-Obstructive Coronary Arteries and Myocardial Infarction with Non-Obstructive Coronary Arteries: Definition, Etiologies, and Role of CT and MR Imaging.

Authors:  Seung Min Yoo; Sowon Jang; Jeong A Kim; Eun Ju Chun
Journal:  Korean J Radiol       Date:  2020-08-11       Impact factor: 3.500

9.  Role of cardiovascular magnetic resonance in the prognosis of patients with myocardial infarction with non-obstructive coronary arteries.

Authors:  Nuria Vicente-Ibarra; Eloisa Feliu; Vicente Bertomeu-Martínez; Pedro Cano-Vivar; Pilar Carrillo-Sáez; Pedro Morillas; Juan Miguel Ruiz-Nodar
Journal:  J Cardiovasc Magn Reson       Date:  2021-07-01       Impact factor: 5.364

  9 in total

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