Literature DB >> 22456734

The role of ATM in response to metformin treatment and activation of AMPK.

Kaixin Zhou, Celine Bellenguez, Calum Sutherland, Grahame Hardie, Colin Palmer, Peter Donnelly, Ewan Pearson.   

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Year:  2012        PMID: 22456734     DOI: 10.1038/ng.2234

Source DB:  PubMed          Journal:  Nat Genet        ISSN: 1061-4036            Impact factor:   38.330


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  14 in total

1.  The role of ATM in response to metformin treatment and activation of AMPK.

Authors:  Angela Woods; James M Leiper; David Carling
Journal:  Nat Genet       Date:  2012-03-28       Impact factor: 38.330

2.  An unusual form of diabetes mellitus in ataxia telangiectasia.

Authors:  D S Schalch; D E McFarlin; M H Barlow
Journal:  N Engl J Med       Date:  1970-06-18       Impact factor: 91.245

3.  From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.

Authors:  Kiran Musunuru; Alanna Strong; Maria Frank-Kamenetsky; Noemi E Lee; Tim Ahfeldt; Katherine V Sachs; Xiaoyu Li; Hui Li; Nicolas Kuperwasser; Vera M Ruda; James P Pirruccello; Brian Muchmore; Ludmila Prokunina-Olsson; Jennifer L Hall; Eric E Schadt; Carlos R Morales; Sissel Lund-Katz; Michael C Phillips; Jamie Wong; William Cantley; Timothy Racie; Kenechi G Ejebe; Marju Orho-Melander; Olle Melander; Victor Koteliansky; Kevin Fitzgerald; Ronald M Krauss; Chad A Cowan; Sekar Kathiresan; Daniel J Rader
Journal:  Nature       Date:  2010-08-05       Impact factor: 49.962

4.  Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.

Authors:  Marc Foretz; Sophie Hébrard; Jocelyne Leclerc; Elham Zarrinpashneh; Maud Soty; Gilles Mithieux; Kei Sakamoto; Fabrizio Andreelli; Benoit Viollet
Journal:  J Clin Invest       Date:  2010-06-23       Impact factor: 14.808

5.  Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells.

Authors:  Toran Sanli; Ayesha Rashid; Caiqiong Liu; Shane Harding; Robert G Bristow; Jean-Claude Cutz; Gurmit Singh; James Wright; Theodoros Tsakiridis
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-07-07       Impact factor: 7.038

6.  p53 is required for chloroquine-induced atheroprotection but not insulin sensitization.

Authors:  Babak Razani; Chu Feng; Clay F Semenkovich
Journal:  J Lipid Res       Date:  2010-03-05       Impact factor: 5.922

7.  The role of ATM in response to metformin treatment and activation of AMPK.

Authors:  Sook Wah Yee; Ligong Chen; Kathleen M Giacomini
Journal:  Nat Genet       Date:  2012-03-28       Impact factor: 38.330

8.  Mechanisms underlying metformin-induced secretion of glucagon-like peptide-1 from the intestinal L cell.

Authors:  Andrew J Mulherin; Amy H Oh; Helena Kim; Anthony Grieco; Lina M Lauffer; Patricia L Brubaker
Journal:  Endocrinology       Date:  2011-10-04       Impact factor: 4.736

9.  ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.

Authors:  Jochen G Schneider; Brian N Finck; Jie Ren; Kara N Standley; Masatoshi Takagi; Kirsteen H Maclean; Carlos Bernal-Mizrachi; Anthony J Muslin; Michael B Kastan; Clay F Semenkovich
Journal:  Cell Metab       Date:  2006-11       Impact factor: 27.287

10.  AICAR induces phosphorylation of AMPK in an ATM-dependent, LKB1-independent manner.

Authors:  Yan Sun; Katie E Connors; Da-Qing Yang
Journal:  Mol Cell Biochem       Date:  2007-09-05       Impact factor: 3.396

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  10 in total

Review 1.  The role of pharmacogenetics in drug disposition and response of oral glucose-lowering drugs.

Authors:  N van Leeuwen; J J Swen; H-J Guchelaar; L M 't Hart
Journal:  Clin Pharmacokinet       Date:  2013-10       Impact factor: 6.447

Review 2.  The genetics of drug efficacy: opportunities and challenges.

Authors:  Matthew R Nelson; Toby Johnson; Liling Warren; Arlene R Hughes; Stephanie L Chissoe; Chun-Fang Xu; Dawn M Waterworth
Journal:  Nat Rev Genet       Date:  2016-03-14       Impact factor: 53.242

3.  A role for ataxia telangiectasia mutated in insulin-independent stimulation of glucose transport.

Authors:  Larry D Spears; Allyson L Renth; Michael R McKuin; Anne R Kennedy; Stanley Andrisse; Nell E Briggs; Jonathan S Fisher
Journal:  Trends Cell Mol Biol       Date:  2017

Review 4.  A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer.

Authors:  Ayesha S Khan; Daniel E Frigo
Journal:  Nat Rev Urol       Date:  2017-02-01       Impact factor: 14.432

Review 5.  The genetic and epigenetic basis of type 2 diabetes and obesity.

Authors:  A W Drong; C M Lindgren; M I McCarthy
Journal:  Clin Pharmacol Ther       Date:  2012-10-10       Impact factor: 6.875

6.  Metformin: On Ongoing Journey across Diabetes, Cancer Therapy and Prevention.

Authors:  Claudio Pulito; Toran Sanli; Punam Rana; Paola Muti; Giovanni Blandino; Sabrina Strano
Journal:  Metabolites       Date:  2013-11-07

Review 7.  Recent advances in the use of metformin: can treating diabetes prevent breast cancer?

Authors:  Diana Hatoum; Eileen M McGowan
Journal:  Biomed Res Int       Date:  2015-03-19       Impact factor: 3.411

8.  Activation of AMPK by metformin promotes renal cancer cell proliferation under glucose deprivation through its interaction with PKM2.

Authors:  Meihan Liu; Zhuo Zhang; Hui Wang; Xiaoliang Chen; Chunxiang Jin
Journal:  Int J Biol Sci       Date:  2019-01-01       Impact factor: 6.580

9.  Phenformin and ataxia-telangiectasia mutated inhibitors synergistically co-suppress liver cancer cell growth by damaging mitochondria.

Authors:  Tianyu Wu; Sichun Zhou; Mei Qin; Jing Tang; Xinjian Yan; Lingli Huang; Meiyuan Huang; Jun Deng; Di Xiao; Xin Hu; Jingtao Wu; Xiaoping Yang; Gaofeng Li
Journal:  FEBS Open Bio       Date:  2021-04-03       Impact factor: 2.693

10.  Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs.

Authors:  Bruna Corominas-Faja; Rosa Quirantes-Piné; Cristina Oliveras-Ferraros; Alejandro Vazquez-Martin; Sílvia Cufí; Begoña Martin-Castillo; Vicente Micol; Jorge Joven; Antonio Segura-Carretero; Javier A Menendez
Journal:  Aging (Albany NY)       Date:  2012-07       Impact factor: 5.682

  10 in total

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