Literature DB >> 22456733

The role of ATM in response to metformin treatment and activation of AMPK.

Angela Woods, James M Leiper, David Carling.   

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Year:  2012        PMID： 22456733     DOI： 10.1038/ng.2235

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


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  10 in total

1.  Effects of culture duration on hydrogen peroxide-induced hepatocyte toxicity.

Authors:  R J Ruch; K A Crist; J E Klaunig
Journal:  Toxicol Appl Pharmacol       Date:  1989-09-15       Impact factor: 4.219

2.  Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.

Authors:  Marc Foretz; Sophie Hébrard; Jocelyne Leclerc; Elham Zarrinpashneh; Maud Soty; Gilles Mithieux; Kei Sakamoto; Fabrizio Andreelli; Benoit Viollet
Journal:  J Clin Invest       Date:  2010-06-23       Impact factor: 14.808

3.  ATM activation by oxidative stress.

Authors:  Zhi Guo; Sergei Kozlov; Martin F Lavin; Maria D Person; Tanya T Paull
Journal:  Science       Date:  2010-10-22       Impact factor: 47.728

4.  Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

Authors:  J N Sarkaria; E C Busby; R S Tibbetts; P Roos; Y Taya; L M Karnitz; R T Abraham
Journal:  Cancer Res       Date:  1999-09-01       Impact factor: 12.701

5.  Role of AMP-activated protein kinase in mechanism of metformin action.

Authors:  G Zhou; R Myers; Y Li; Y Chen; X Shen; J Fenyk-Melody; M Wu; J Ventre; T Doebber; N Fujii; N Musi; M F Hirshman; L J Goodyear; D E Moller
Journal:  J Clin Invest       Date:  2001-10       Impact factor: 14.808

6.  Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.

Authors:  Yan Shu; Steven A Sheardown; Chaline Brown; Ryan P Owen; Shuzhong Zhang; Richard A Castro; Alexandra G Ianculescu; Lin Yue; Joan C Lo; Esteban G Burchard; Claire M Brett; Kathleen M Giacomini
Journal:  J Clin Invest       Date:  2007-05       Impact factor: 14.808

7.  A single ataxia telangiectasia gene with a product similar to PI-3 kinase.

Authors:  K Savitsky; A Bar-Shira; S Gilad; G Rotman; Y Ziv; L Vanagaite; D A Tagle; S Smith; T Uziel; S Sfez; M Ashkenazi; I Pecker; M Frydman; R Harnik; S R Patanjali; A Simmons; G A Clines; A Sartiel; R A Gatti; L Chessa; O Sanal; M F Lavin; N G Jaspers; A M Taylor; C F Arlett; T Miki; S M Weissman; M Lovett; F S Collins; Y Shiloh
Journal:  Science       Date:  1995-06-23       Impact factor: 47.728

Review 8.  AMP-activated protein kinase: nature's energy sensor.

Authors:  David Carling; Faith V Mayer; Matthew J Sanders; Steven J Gamblin
Journal:  Nat Chem Biol       Date:  2011-07-18       Impact factor: 15.040

9.  Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.

Authors:  Kaixin Zhou; Celine Bellenguez; Chris C A Spencer; Amanda J Bennett; Ruth L Coleman; Roger Tavendale; Simon A Hawley; Louise A Donnelly; Chris Schofield; Christopher J Groves; Lindsay Burch; Fiona Carr; Amy Strange; Colin Freeman; Jenefer M Blackwell; Elvira Bramon; Matthew A Brown; Juan P Casas; Aiden Corvin; Nicholas Craddock; Panos Deloukas; Serge Dronov; Audrey Duncanson; Sarah Edkins; Emma Gray; Sarah Hunt; Janusz Jankowski; Cordelia Langford; Hugh S Markus; Christopher G Mathew; Robert Plomin; Anna Rautanen; Stephen J Sawcer; Nilesh J Samani; Richard Trembath; Ananth C Viswanathan; Nicholas W Wood; Lorna W Harries; Andrew T Hattersley; Alex S F Doney; Helen Colhoun; Andrew D Morris; Calum Sutherland; D Grahame Hardie; Leena Peltonen; Mark I McCarthy; Rury R Holman; Colin N A Palmer; Peter Donnelly; Ewan R Pearson
Journal:  Nat Genet       Date:  2010-12-26       Impact factor: 38.330

10.  LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice.

Authors:  Angela Woods; Amanda J Heslegrave; Phillip J Muckett; Adam P Levene; Melanie Clements; Margaret Mobberley; Timothy A Ryder; Shadi Abu-Hayyeh; Catherine Williamson; Robert D Goldin; Alan Ashworth; Dominic J Withers; David Carling
Journal:  Biochem J       Date:  2011-02-15       Impact factor: 3.857
  10 in total
  10 in total

1.  The role of ATM in response to metformin treatment and activation of AMPK.

Authors:  Kaixin Zhou; Celine Bellenguez; Calum Sutherland; Grahame Hardie; Colin Palmer; Peter Donnelly; Ewan Pearson
Journal:  Nat Genet       Date:  2012-03-28       Impact factor: 38.330

Review 2.  The role of pharmacogenetics in drug disposition and response of oral glucose-lowering drugs.

Authors:  N van Leeuwen; J J Swen; H-J Guchelaar; L M 't Hart
Journal:  Clin Pharmacokinet       Date:  2013-10       Impact factor: 6.447

Review 3.  Metformin as an Adjunctive Therapy for Pancreatic Cancer: A Review of the Literature on Its Potential Therapeutic Use.

Authors:  Philip J Broadhurst; Andrew R Hart
Journal:  Dig Dis Sci       Date:  2018-08-29       Impact factor: 3.199

4.  A role for ataxia telangiectasia mutated in insulin-independent stimulation of glucose transport.

Authors:  Larry D Spears; Allyson L Renth; Michael R McKuin; Anne R Kennedy; Stanley Andrisse; Nell E Briggs; Jonathan S Fisher
Journal:  Trends Cell Mol Biol       Date:  2017

Review 5.  A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer.

Authors:  Ayesha S Khan; Daniel E Frigo
Journal:  Nat Rev Urol       Date:  2017-02-01       Impact factor: 14.432

Review 6.  AMP-activated protein kinase (AMPK) beyond metabolism: a novel genomic stress sensor participating in the DNA damage response pathway.

Authors:  Toran Sanli; Gregory R Steinberg; Gurmit Singh; Theodoros Tsakiridis
Journal:  Cancer Biol Ther       Date:  2013-11-01       Impact factor: 4.742

7.  Metformin pharmacogenomics: current status and future directions.

Authors:  Aaron C Pawlyk; Kathleen M Giacomini; Catherine McKeon; Alan R Shuldiner; Jose C Florez
Journal:  Diabetes       Date:  2014-08       Impact factor: 9.461

8.  Metformin pharmacogenomics: biomarkers to mechanisms.

Authors:  Liewei Wang; Richard Weinshilboum
Journal:  Diabetes       Date:  2014-08       Impact factor: 9.461

9.  Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin.

Authors:  Mahvash Zakikhani; Miguel Bazile; Sina Hashemi; Shiva Javeshghani; Daina Avizonis; Julie St Pierre; Michael N Pollak
Journal:  PLoS One       Date:  2012-11-21       Impact factor: 3.240

10.  Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs.

Authors:  Bruna Corominas-Faja; Rosa Quirantes-Piné; Cristina Oliveras-Ferraros; Alejandro Vazquez-Martin; Sílvia Cufí; Begoña Martin-Castillo; Vicente Micol; Jorge Joven; Antonio Segura-Carretero; Javier A Menendez
Journal:  Aging (Albany NY)       Date:  2012-07       Impact factor: 5.682
  10 in total

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