Literature DB >> 22456732

The role of ATM in response to metformin treatment and activation of AMPK.

Sook Wah Yee, Ligong Chen, Kathleen M Giacomini.   

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Year:  2012        PMID： 22456732      PMCID： PMC3359140          DOI： 10.1038/ng.2236

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


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  11 in total

1.  Activation of the ATM kinase by ionizing radiation and phosphorylation of p53.

Authors:  C E Canman; D S Lim; K A Cimprich; Y Taya; K Tamai; K Sakaguchi; E Appella; M B Kastan; J D Siliciano
Journal:  Science       Date:  1998-09-11       Impact factor: 47.728

2.  Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.

Authors:  Marc Foretz; Sophie Hébrard; Jocelyne Leclerc; Elham Zarrinpashneh; Maud Soty; Gilles Mithieux; Kei Sakamoto; Fabrizio Andreelli; Benoit Viollet
Journal:  J Clin Invest       Date:  2010-06-23       Impact factor: 14.808

3.  Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells.

Authors:  Toran Sanli; Ayesha Rashid; Caiqiong Liu; Shane Harding; Robert G Bristow; Jean-Claude Cutz; Gurmit Singh; James Wright; Theodoros Tsakiridis
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-07-07       Impact factor: 7.038

4.  Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions.

Authors:  G Ahlin; L Chen; L Lazorova; Y Chen; A G Ianculescu; R L Davis; K M Giacomini; P Artursson
Journal:  Pharmacogenomics J       Date:  2010-06-22       Impact factor: 3.550

5.  Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin.

Authors:  Ligong Chen; Bradley Pawlikowski; Avner Schlessinger; Swati S More; Doug Stryke; Susan J Johns; Michael A Portman; Eugene Chen; Thomas E Ferrin; Andrej Sali; Kathleen M Giacomini
Journal:  Pharmacogenet Genomics       Date:  2010-11       Impact factor: 2.089

6.  Role of AMP-activated protein kinase in mechanism of metformin action.

Authors:  G Zhou; R Myers; Y Li; Y Chen; X Shen; J Fenyk-Melody; M Wu; J Ventre; T Doebber; N Fujii; N Musi; M F Hirshman; L J Goodyear; D E Moller
Journal:  J Clin Invest       Date:  2001-10       Impact factor: 14.808

7.  Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.

Authors:  Yan Shu; Steven A Sheardown; Chaline Brown; Ryan P Owen; Shuzhong Zhang; Richard A Castro; Alexandra G Ianculescu; Lin Yue; Joan C Lo; Esteban G Burchard; Claire M Brett; Kathleen M Giacomini
Journal:  J Clin Invest       Date:  2007-05       Impact factor: 14.808

8.  AICAR induces phosphorylation of AMPK in an ATM-dependent, LKB1-independent manner.

Authors:  Yan Sun; Katie E Connors; Da-Qing Yang
Journal:  Mol Cell Biochem       Date:  2007-09-05       Impact factor: 3.396

9.  Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.

Authors:  Kaixin Zhou; Celine Bellenguez; Chris C A Spencer; Amanda J Bennett; Ruth L Coleman; Roger Tavendale; Simon A Hawley; Louise A Donnelly; Chris Schofield; Christopher J Groves; Lindsay Burch; Fiona Carr; Amy Strange; Colin Freeman; Jenefer M Blackwell; Elvira Bramon; Matthew A Brown; Juan P Casas; Aiden Corvin; Nicholas Craddock; Panos Deloukas; Serge Dronov; Audrey Duncanson; Sarah Edkins; Emma Gray; Sarah Hunt; Janusz Jankowski; Cordelia Langford; Hugh S Markus; Christopher G Mathew; Robert Plomin; Anna Rautanen; Stephen J Sawcer; Nilesh J Samani; Richard Trembath; Ananth C Viswanathan; Nicholas W Wood; Lorna W Harries; Andrew T Hattersley; Alex S F Doney; Helen Colhoun; Andrew D Morris; Calum Sutherland; D Grahame Hardie; Leena Peltonen; Mark I McCarthy; Rury R Holman; Colin N A Palmer; Peter Donnelly; Ewan R Pearson
Journal:  Nat Genet       Date:  2010-12-26       Impact factor: 38.330

10.  Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation.

Authors:  Xuan Fu; Shan Wan; Yi Lisa Lyu; Leroy F Liu; Haiyan Qi
Journal:  PLoS One       Date:  2008-04-23       Impact factor: 3.240
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  21 in total

1.  The role of ATM in response to metformin treatment and activation of AMPK.

Authors:  Kaixin Zhou; Celine Bellenguez; Calum Sutherland; Grahame Hardie; Colin Palmer; Peter Donnelly; Ewan Pearson
Journal:  Nat Genet       Date:  2012-03-28       Impact factor: 38.330

Review 2.  Metformin pathways: pharmacokinetics and pharmacodynamics.

Authors:  Li Gong; Srijib Goswami; Kathleen M Giacomini; Russ B Altman; Teri E Klein
Journal:  Pharmacogenet Genomics       Date:  2012-11       Impact factor: 2.089

3.  Activation of AMPK attenuates LPS-induced acute lung injury by upregulation of PGC1α and SOD1.

Authors:  Guizuo Wang; Yang Song; Wei Feng; Lu Liu; Yanting Zhu; Xinming Xie; Yilin Pan; Rui Ke; Shaojun Li; Fangwei Li; Lan Yang; Manxiang Li
Journal:  Exp Ther Med       Date:  2016-06-17       Impact factor: 2.447

Review 4.  Metformin as an Adjunctive Therapy for Pancreatic Cancer: A Review of the Literature on Its Potential Therapeutic Use.

Authors:  Philip J Broadhurst; Andrew R Hart
Journal:  Dig Dis Sci       Date:  2018-08-29       Impact factor: 3.199

5.  A Genetic Interaction Map of Insulin Production Identifies Mfi as an Inhibitor of Mitochondrial Fission.

Authors:  Jessica Lee; Zachary Pappalardo; Deeksha Gambhir Chopra; Thomas G Hennings; Ian Vaughn; Christopher Lan; Justin J Choe; Kenny Ang; Steven Chen; Michelle Arkin; Michael T McManus; Michael S German; Gregory M Ku
Journal:  Endocrinology       Date:  2018-09-01       Impact factor: 4.736

6.  A role for ataxia telangiectasia mutated in insulin-independent stimulation of glucose transport.

Authors:  Larry D Spears; Allyson L Renth; Michael R McKuin; Anne R Kennedy; Stanley Andrisse; Nell E Briggs; Jonathan S Fisher
Journal:  Trends Cell Mol Biol       Date:  2017

Review 7.  A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer.

Authors:  Ayesha S Khan; Daniel E Frigo
Journal:  Nat Rev Urol       Date:  2017-02-01       Impact factor: 14.432

8.  Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.

Authors:  Ping Yuan; Koichi Ito; Rolando Perez-Lorenzo; Christina Del Guzzo; Jung Hyun Lee; Che-Hung Shen; Marcus W Bosenberg; Martin McMahon; Lewis C Cantley; Bin Zheng
Journal:  Proc Natl Acad Sci U S A       Date:  2013-10-21       Impact factor: 11.205

Review 9.  Pharmacogenetics: Implications for Modern Type 2 Diabetes Therapy.

Authors:  Harald Staiger; Elke Schaeffeler; Matthias Schwab; Hans-Ulrich Häring
Journal:  Rev Diabet Stud       Date:  2016-02-10

Review 10.  An update on the pharmacogenomics of metformin: progress, problems and potential.

Authors:  Jennifer N Todd; Jose C Florez
Journal:  Pharmacogenomics       Date:  2014-03       Impact factor: 2.533
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