Literature DB >> 22451336

Better function for fusions versus above-the-knee amputations for recurrent periprosthetic knee infection.

Antonia F Chen1, Nicholas C Kinback, Alma E Heyl, Edward J McClain, Brian A Klatt.   

Abstract

BACKGROUND: Treatment of chronic periprosthetic joint infections (PJIs) after TKA is limited to fusions, above-the-knee amputations (AKAs), revision TKA, and antibiotic suppression and is often based on the patient's medical condition. However, when both fusion and AKA are options, it is important to compare these two procedures with regard to function. QUESTIONS/PURPOSES: Do patients receiving a knee fusion for PJI after TKA have better function compared to patients receiving an AKA?
METHODS: We retrospectively reviewed patients who were eligible for either fusion or AKA after PJI TKA. Thirty-seven patients underwent a fusion for PJIs after TKA between 1999 and 2010. Nine patients died postoperatively and eight patients were lost to followup, leaving 20 patients. Patients completed a specialized questionnaire about their fusion, and functional capability was assessed by the SF-12. We compared fusions to a previously published group of six patients who underwent AKA for recurrent PJI after TKA.
RESULTS: For patients with fusion, community ambulators increased from five to 10 and nonambulators decreased from three to one. For patients with AKA, nonambulatory patients increased from zero to two, and community ambulators decreased from four to one. The SF-12 physical component summary measurements were higher for fusions (51) than for AKAs (26). The mental component summary was also higher in fusions (60) than in AKAs (44). Seventy percent of patients indicated they would undergo a fusion again instead of undergoing an amputation if they were presented with both options after undergoing their operation.
CONCLUSIONS: Patients receiving knee fusions for treating recurrent PJIs after TKA have better function and ambulatory status compared to patients receiving AKA. LEVEL OF EVIDENCE: Level III, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.

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Year:  2012        PMID: 22451336      PMCID: PMC3441991          DOI: 10.1007/s11999-012-2322-7

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  57 in total

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9.  Two-stage reimplantation for the salvage of total knee arthroplasty complicated by infection. Further follow-up and refinement of indications.

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Authors:  Z U Isiklar; G C Landon; H S Tullos
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  15 in total

Review 1.  [Treatment of periprosthetic infections].

Authors:  L Renner; C Perka; A Trampuz; N Renz
Journal:  Chirurg       Date:  2016-10       Impact factor: 0.955

2.  Knee arthrodesis with a long intramedullary nail as limb salvage for complex periprosthetic infections.

Authors:  Nima Razii; Ammar M I Abbas; Rahul Kakar; Sanjeev Agarwal; Rhidian Morgan-Jones
Journal:  Eur J Orthop Surg Traumatol       Date:  2016-07-29

Review 3.  Arthrodesis should be strongly considered after failed two-stage reimplantation TKA.

Authors:  Chia H Wu; Chancellor F Gray; Gwo-Chin Lee
Journal:  Clin Orthop Relat Res       Date:  2014-11       Impact factor: 4.176

4.  What Are the Frequency, Associated Factors, and Mortality of Amputation and Arthrodesis After a Failed Infected TKA?

Authors:  Min-Sun Son; Edmund Lau; Javad Parvizi; Michael A Mont; Kevin J Bozic; Steven Kurtz
Journal:  Clin Orthop Relat Res       Date:  2017-12       Impact factor: 4.176

Review 5.  [Reconstruction of the extensor apparatus with advanced structural defects in knee revision arthroplasty].

Authors:  K Welle; R K Hackenberg; K Kabir; I Habicht; D C Wirtz; H Kohlhof
Journal:  Oper Orthop Traumatol       Date:  2021-11-04       Impact factor: 1.154

6.  Success after treatment of periprosthetic joint infection: a Delphi-based international multidisciplinary consensus.

Authors:  Claudio Diaz-Ledezma; Carlos A Higuera; Javad Parvizi
Journal:  Clin Orthop Relat Res       Date:  2013-02-26       Impact factor: 4.176

Review 7.  Knee Fusion or Above-The-Knee Amputation after Failed Two-Stage Reimplantation Total Knee Arthroplasty.

Authors:  E Carlos Rodriguez-Merchan
Journal:  Arch Bone Jt Surg       Date:  2015-10

8.  High Rate of Fusion but High Complication Rate After Knee Arthrodesis for Infected Revision Total Knee Replacement.

Authors:  Gustavo Aparicio; Julio Otero; Silvia Bru
Journal:  Indian J Orthop       Date:  2020-06-04       Impact factor: 1.251

9.  What Is the Mid-term Survivorship of Infected Rotating-hinge Implants Treated with One-stage-exchange?

Authors:  Malte Ohlmeier; Fadi Alrustom; Mustafa Citak; Jochen Salber; Thorsten Gehrke; Jannik Frings
Journal:  Clin Orthop Relat Res       Date:  2021-12-01       Impact factor: 4.176

Review 10.  Periprosthetic knee infection: ten strategies that work.

Authors:  Javad Parvizi; Priscilla Ku Cavanaugh; Claudio Diaz-Ledezma
Journal:  Knee Surg Relat Res       Date:  2013-11-29
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