BACKGROUND: Assessing collateral status is important in acute ischemic stroke. The purpose of this study was to compare multiphasic perfusion computed tomography (MPCT) with digital subtraction angiography (DSA) in predicting leptomeningeal collateral flow in acute middle cerebral artery (MCA) infarction. METHODS: Consecutive patients underwent MPCT and DSA for acute MCA infarction that presented within 6 h of symptom onset. We included patients who showed MCA occlusion in the same location on both modalities and assessed the agreement rate and correlation between the MPCT and DSA collateral grades. RESULTS: Of 54 patients, 44 (81.5%) had proximal MCA (M1) occlusions and 10 (18.5%) had distal MCA (M2) occlusions based on MPCT and DSA. The κ-coefficients were 0.87 and 0.81 in the MPCT and DSA collateral grade systems, respectively. Forty-four patients (81.5%) belonged to the same category in both collateral-grading systems. MPCT collateral grades correlated positively with those of DSA (Spearman's correlation coefficient 0.827, p < 0.001). CONCLUSION: Our data show that MPCT can predict leptomeningeal collateral flow in acute ischemic stroke. Based on collateral status assessed by MPCT, different therapeutic approaches might be warranted.
BACKGROUND: Assessing collateral status is important in acute ischemic stroke. The purpose of this study was to compare multiphasic perfusion computed tomography (MPCT) with digital subtraction angiography (DSA) in predicting leptomeningeal collateral flow in acute middle cerebral artery (MCA) infarction. METHODS: Consecutive patients underwent MPCT and DSA for acute MCA infarction that presented within 6 h of symptom onset. We included patients who showed MCA occlusion in the same location on both modalities and assessed the agreement rate and correlation between the MPCT and DSA collateral grades. RESULTS: Of 54 patients, 44 (81.5%) had proximal MCA (M1) occlusions and 10 (18.5%) had distal MCA (M2) occlusions based on MPCT and DSA. The κ-coefficients were 0.87 and 0.81 in the MPCT and DSA collateral grade systems, respectively. Forty-four patients (81.5%) belonged to the same category in both collateral-grading systems. MPCT collateral grades correlated positively with those of DSA (Spearman's correlation coefficient 0.827, p < 0.001). CONCLUSION: Our data show that MPCT can predict leptomeningeal collateral flow in acute ischemic stroke. Based on collateral status assessed by MPCT, different therapeutic approaches might be warranted.
Authors: I G H Jansen; O A Berkhemer; A J Yoo; J A Vos; G J Lycklama À Nijeholt; M E S Sprengers; W H van Zwam; W J Schonewille; J Boiten; M A A van Walderveen; R J van Oostenbrugge; A van der Lugt; H A Marquering; C B L M Majoie Journal: AJNR Am J Neuroradiol Date: 2016-07-14 Impact factor: 3.825
Authors: Mina Park; Kyung-Eun Kim; Na-Young Shin; Seung-Koo Lee; Soo Mee Lim; Dongbeom Song; Ji Hoe Heo; Jin Woo Kim; Se Won Oh Journal: Eur Radiol Date: 2015-09-22 Impact factor: 5.315
Authors: Andreas M J Frölich; Sarah Lena Wolff; Marios N Psychogios; Ernst Klotz; Ramona Schramm; Katrin Wasser; Michael Knauth; Peter Schramm Journal: Eur Radiol Date: 2014-02 Impact factor: 5.315
Authors: Na-Young Shin; Kyung-eun Kim; Mina Park; Young Dae Kim; Dong Joon Kim; Sung Jun Ahn; Ji Hoe Heo; Seung-Koo Lee Journal: PLoS One Date: 2014-09-11 Impact factor: 3.240