Literature DB >> 22437158

A highly enantioselective approach towards 2-substituted 3-bromopyrrolidines.

Jie Chen1, Ling Zhou, Ying-Yeung Yeung.   

Abstract

A facile and highly enantioselective approach towards 2-substituted 3-bromopyrrolidines has been developed. The process involves an amino-thiocarbamate catalyzed bromoaminocyclization of 1,2-disubstituted olefinic amides. The pyrrolidine products could readily be converted into other useful building blocks including a dihydropyrrole and a 2-substituted pyrrolidine.

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Year:  2012        PMID： 22437158     DOI： 10.1039/c2ob25327e

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  5 in total

1.  Synthesis of 2-Aryl- and 2-Vinylpyrrolidines via Copper-Catalyzed Coupling of Styrenes and Dienes with Potassium β-Aminoethyl Trifluoroborates.

Authors:  Chanchamnan Um; Sherry R Chemler
Journal:  Org Lett       Date:  2016-05-10       Impact factor: 6.005

2.  Catalytic Aminohalogenation of Alkenes and Alkynes.

Authors:  Sherry R Chemler; Michael T Bovino
Journal:  ACS Catal       Date:  2013-06-07       Impact factor: 13.084

Review 3.  Catalytic, asymmetric halofunctionalization of alkenes--a critical perspective.

Authors:  Scott E Denmark; William E Kuester; Matthew T Burk
Journal:  Angew Chem Int Ed Engl       Date:  2012-09-25       Impact factor: 15.336

4.  Highly Stereoselective Intermolecular Haloetherification and Haloesterification of Allyl Amides.

Authors:  Bardia Soltanzadeh; Arvind Jaganathan; Richard J Staples; Babak Borhan
Journal:  Angew Chem Int Ed Engl       Date:  2015-06-25       Impact factor: 15.336

5.  2-[1'-(Benz-yloxy)spiro-[indane-1,2'-pyrrolidine]-5'-yl]aceto-nitrile.

Authors:  Rodolfo Moreno-Fuquen; Diana M Soto; Luz M Jaramillo-Gómez; Javier Ellena; Juan C Tenorio
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-07-03
  5 in total

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