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Literature DB >> 22433838

Lrig1: a new master regulator of epithelial stem cells.

Paloma Ordóñez-Morán¹, Joerg Huelsken.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2012 PMID： 22433838 PMCID： PMC3343471 DOI： 10.1038/emboj.2012.73

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

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10 in total

1. Interconversion between intestinal stem cell populations in distinct niches.

Authors: Norifumi Takeda; Rajan Jain; Matthew R LeBoeuf; Qiaohong Wang; Min Min Lu; Jonathan A Epstein
Journal: Science Date: 2011-11-10 Impact factor: 47.728

2. Growth retardation, duodenal lesions, and aberrant ileum architecture in triple null mice lacking EGF, amphiregulin, and TGF-alpha.

Authors: K L Troyer; N C Luetteke; M L Saxon; T H Qiu; C J Xian; D C Lee
Journal: Gastroenterology Date: 2001-07 Impact factor: 22.682

Review 3. Current view: intestinal stem cells and signaling.

Authors: David H Scoville; Toshiro Sato; Xi C He; Linheng Li
Journal: Gastroenterology Date: 2008-03 Impact factor: 22.682

4. A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable.

Authors: Hua Tian; Brian Biehs; Søren Warming; Kevin G Leong; Linda Rangell; Ophir D Klein; Frederic J de Sauvage
Journal: Nature Date: 2011-09-18 Impact factor: 49.962

5. Mice lacking transforming growth factor alpha have an increased susceptibility to dextran sulfate-induced colitis.

Authors: B Egger; F Procaccino; J Lakshmanan; M Reinshagen; P Hoffmann; A Patel; W Reuben; S Gnanakkan; L Liu; L Barajas; V E Eysselein
Journal: Gastroenterology Date: 1997-09 Impact factor: 22.682

Review 6. LRIG inhibitors of growth factor signalling - double-edged swords in human cancer?

Authors: Håkan Hedman; Roger Henriksson
Journal: Eur J Cancer Date: 2007-01-18 Impact factor: 9.162

7. Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling.

Authors: Tina L Gumienny; Lesley Macneil; Cole M Zimmerman; Huang Wang; Lena Chin; Jeffrey L Wrana; Richard W Padgett
Journal: PLoS Genet Date: 2010-05-20 Impact factor: 5.917

8. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer.

Authors: David Cunningham; Yves Humblet; Salvatore Siena; David Khayat; Harry Bleiberg; Armando Santoro; Danny Bets; Matthias Mueser; Andreas Harstrick; Chris Verslype; Ian Chau; Eric Van Cutsem
Journal: N Engl J Med Date: 2004-07-22 Impact factor: 91.245

9. Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling.

Authors: Vivian W Y Wong; Daniel E Stange; Mahalia E Page; Simon Buczacki; Agnieszka Wabik; Satoshi Itami; Marc van de Wetering; Richard Poulsom; Nicholas A Wright; Matthew W B Trotter; Fiona M Watt; Doug J Winton; Hans Clevers; Kim B Jensen
Journal: Nat Cell Biol Date: 2012-03-04 Impact factor: 28.824

10. Epidermal stem cell diversity and quiescence.

Authors: Fiona M Watt; Kim B Jensen
Journal: EMBO Mol Med Date: 2009-08 Impact factor: 12.137

10 in total

12 in total

Lrig1: a new master regulator of epithelial stem cells.

1. Interconversion between intestinal stem cell populations in distinct niches.

2. Growth retardation, duodenal lesions, and aberrant ileum architecture in triple null mice lacking EGF, amphiregulin, and TGF-alpha.

Review 3. Current view: intestinal stem cells and signaling.

4. A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable.

5. Mice lacking transforming growth factor alpha have an increased susceptibility to dextran sulfate-induced colitis.

Review 6. LRIG inhibitors of growth factor signalling - double-edged swords in human cancer?

7. Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling.

8. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer.

9. Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling.

10. Epidermal stem cell diversity and quiescence.

1. Stochastic control of proliferation and differentiation in stem cell dynamics.

Review 2. Wnt/β-catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration.

3. Analysis of stochastic stem cell models with control.

4. NTPDase2+ Cells Generate Lingual Epithelia and Papillae.

5. Principles of regulation of self-renewing cell lineages.

6. Symmetric vs. asymmetric stem cell divisions: an adaptation against cancer?

7. A compendium of developmental gene expression in Lake Malawi cichlid fishes.

Review 8. Intestinal Stem Cell Niche Insights Gathered from Both In Vivo and Novel In Vitro Models.

9. Loss of LRIG1 locus increases risk of early and late relapse of stage I/II breast cancer.

10. USP8 modulates ubiquitination of LRIG1 for Met degradation.