Literature DB >> 22431243

Protein oriented ligation on nanoparticles exploiting O6-alkylguanine-DNA transferase (SNAP) genetically encoded fusion.

Miriam Colombo1, Serena Mazzucchelli, Josè Maria Montenegro, Elisabetta Galbiati, Fabio Corsi, Wolfgang J Parak, Davide Prosperi.   

Abstract

A bimodular genetic fusion comprising a delivery module (scFv) and a capture module (SNAP) is proposed as a novel strategy for the site-specific covalent conjugation of targeting peptides to nanoparticles. An scFv mutant selective for HER2 tumor antigen is chosen as the targeting ligand. SNAP-scFv is immobilized on magnetofluorescent nanoparticles and its targeting efficiency against HER2-positive cells is assessed by flow cytometry and immunofluorescence.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID: 22431243     DOI: 10.1002/smll.201102284

Source DB:  PubMed          Journal:  Small        ISSN: 1613-6810            Impact factor:   13.281


  14 in total

1.  X-ray-Based Techniques to Study the Nano-Bio Interface.

Authors:  Carlos Sanchez-Cano; Ramon A Alvarez-Puebla; John M Abendroth; Tobias Beck; Robert Blick; Yuan Cao; Frank Caruso; Indranath Chakraborty; Henry N Chapman; Chunying Chen; Bruce E Cohen; Andre L C Conceição; David P Cormode; Daxiang Cui; Kenneth A Dawson; Gerald Falkenberg; Chunhai Fan; Neus Feliu; Mingyuan Gao; Elisabetta Gargioni; Claus-C Glüer; Florian Grüner; Moustapha Hassan; Yong Hu; Yalan Huang; Samuel Huber; Nils Huse; Yanan Kang; Ali Khademhosseini; Thomas F Keller; Christian Körnig; Nicholas A Kotov; Dorota Koziej; Xing-Jie Liang; Beibei Liu; Sijin Liu; Yang Liu; Ziyao Liu; Luis M Liz-Marzán; Xiaowei Ma; Andres Machicote; Wolfgang Maison; Adrian P Mancuso; Saad Megahed; Bert Nickel; Ferdinand Otto; Cristina Palencia; Sakura Pascarelli; Arwen Pearson; Oula Peñate-Medina; Bing Qi; Joachim Rädler; Joseph J Richardson; Axel Rosenhahn; Kai Rothkamm; Michael Rübhausen; Milan K Sanyal; Raymond E Schaak; Heinz-Peter Schlemmer; Marius Schmidt; Oliver Schmutzler; Theo Schotten; Florian Schulz; A K Sood; Kathryn M Spiers; Theresa Staufer; Dominik M Stemer; Andreas Stierle; Xing Sun; Gohar Tsakanova; Paul S Weiss; Horst Weller; Fabian Westermeier; Ming Xu; Huijie Yan; Yuan Zeng; Ying Zhao; Yuliang Zhao; Dingcheng Zhu; Ying Zhu; Wolfgang J Parak
Journal:  ACS Nano       Date:  2021-03-02       Impact factor: 15.881

2.  Stable small quantum dots for synaptic receptor tracking on live neurons.

Authors:  En Cai; Pinghua Ge; Sang Hak Lee; Okunola Jeyifous; Yong Wang; Yanxin Liu; Katie M Wilson; Sung Jun Lim; Michelle A Baird; John E Stone; Kwan Young Lee; Michael W Davidson; Hee Jung Chung; Klaus Schulten; Andrew M Smith; William N Green; Paul R Selvin
Journal:  Angew Chem Int Ed Engl       Date:  2014-09-26       Impact factor: 15.336

Review 3.  Fluorescent Nanoparticles for Super-Resolution Imaging.

Authors:  Wei Li; Gabriele S Kaminski Schierle; Bingfu Lei; Yingliang Liu; Clemens F Kaminski
Journal:  Chem Rev       Date:  2022-06-27       Impact factor: 72.087

Review 4.  The pharmacology of plant virus nanoparticles.

Authors:  Christian Isalomboto Nkanga; Nicole F Steinmetz
Journal:  Virology       Date:  2021-01-28       Impact factor: 3.616

5.  Comparison of a mouse and a novel human scFv-SNAP-auristatin F drug conjugate with potent activity against EGFR-overexpressing human solid tumor cells.

Authors:  Mira Woitok; Diana Klose; Stefano Di Fiore; Wolfgang Richter; Christoph Stein; Gerrit Gresch; Elena Grieger; Stefan Barth; Rainer Fischer; Katharina Kolberg; Judith Niesen
Journal:  Onco Targets Ther       Date:  2017-07-06       Impact factor: 4.147

6.  Conjugation of Polymer-Coated Gold Nanoparticles with Antibodies-Synthesis and Characterization.

Authors:  Gamze Tan; Karsten Kantner; Qian Zhang; Mahmoud G Soliman; Pablo Del Pino; Wolfgang J Parak; Mehmet A Onur; Daniel Valdeperez; Joanna Rejman; Beatriz Pelaz
Journal:  Nanomaterials (Basel)       Date:  2015-08-07       Impact factor: 5.076

7.  Silicon particles as trojan horses for potential cancer therapy.

Authors:  Roberto Fenollosa; Eduardo Garcia-Rico; Susana Alvarez; Rosana Alvarez; Xiang Yu; Isabel Rodriguez; Susana Carregal-Romero; Carlos Villanueva; Manuel Garcia-Algar; Pilar Rivera-Gil; Angel R de Lera; Wolfgang J Parak; Francisco Meseguer; Ramón A Alvarez-Puebla
Journal:  J Nanobiotechnology       Date:  2014-09-16       Impact factor: 10.435

Review 8.  In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?

Authors:  Moritz Nazarenus; Qian Zhang; Mahmoud G Soliman; Pablo Del Pino; Beatriz Pelaz; Susana Carregal-Romero; Joanna Rejman; Barbara Rothen-Rutishauser; Martin J D Clift; Reinhard Zellner; G Ulrich Nienhaus; James B Delehanty; Igor L Medintz; Wolfgang J Parak
Journal:  Beilstein J Nanotechnol       Date:  2014-09-09       Impact factor: 3.649

9.  Immobilization of carboxypeptidase from Sulfolobus solfataricus on magnetic nanoparticles improves enzyme stability and functionality in organic media.

Authors:  Silvia Sommaruga; Elisabetta Galbiati; Jesus Peñaranda-Avila; Chiara Brambilla; Paolo Tortora; Miriam Colombo; Davide Prosperi
Journal:  BMC Biotechnol       Date:  2014-09-05       Impact factor: 2.563

Review 10.  New Routes and Opportunities for Modular Construction of Particulate Vaccines: Stick, Click, and Glue.

Authors:  Karl D Brune; Mark Howarth
Journal:  Front Immunol       Date:  2018-06-26       Impact factor: 7.561

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