Literature DB >> 2241574

Mutational analysis of enhancer domains responsive to trans-activation by the X gene of human hepatitis B virus.

G Goodarzi1, H Ohno, R Adams, A Darabi, A Tewari, M Watabe, K Watabe.   

Abstract

The X gene product of human hepatitis B virus (HBV) trans-activates the HBV enhancer. In order to identify domains responsive to trans-activation by the X gene, we introduced a series of mutations into the HBV enhancer and assayed the enhancer activities in the presence of the X gene product. Our results suggest that the EP domain of the enhancer is essential for trans-activation by the X gene.

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Year:  1990        PMID： 2241574     DOI： 10.1007/bf01310752

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  22 in total

1.  trans-activation of viral enhancers by the hepatitis B virus X protein.

Authors:  D F Spandau; C H Lee
Journal:  J Virol       Date:  1988-02       Impact factor: 5.103

2.  A single element within the hepatitis B virus enhancer binds multiple proteins and responds to multiple stimuli.

Authors:  O Faktor; S Budlovsky; R Ben-Levy; Y Shaul
Journal:  J Virol       Date:  1990-04       Impact factor: 5.103

3.  Transcriptional activation of homologous and heterologous genes by the hepatitis B virus X gene product in cells permissive for viral replication.

Authors:  R Colgrove; G Simon; D Ganem
Journal:  J Virol       Date:  1989-09       Impact factor: 5.103

4.  Rapid and efficient site-specific mutagenesis without phenotypic selection.

Authors:  T A Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

5.  Supercoil sequencing: a fast and simple method for sequencing plasmid DNA.

Authors:  E Y Chen; P H Seeburg
Journal:  DNA       Date:  1985-04

6.  Interactions between nuclear factors and the hepatitis B virus enhancer.

Authors:  N U Patel; S Jameel; H Isom; A Siddiqui
Journal:  J Virol       Date:  1989-12       Impact factor: 5.103

7.  Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors.

Authors:  E Seto; P J Mitchell; T S Yen
Journal:  Nature       Date:  1990-03-01       Impact factor: 49.962

8.  Identification of a region within the human immunodeficiency virus type 1 long terminal repeat that is essential for transactivation by the hepatitis B virus gene X.

Authors:  J S Twu; C A Rosen; W A Haseltine; W S Robinson
Journal:  J Virol       Date:  1989-06       Impact factor: 5.103

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  Binding of tissue-specific factors to the enhancer sequence of hepatitis B virus.

Authors:  H W Chou; D Harrell; R Forough; K Watabe
Journal:  FEBS Lett       Date:  1988-03-14       Impact factor: 4.124
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  3 in total

1.  Detection of a hepatitis B virus variant with a truncated X gene and enhancer II.

Authors:  R Repp; C Keller; A Borkhardt; A Csecke; S Schaefer; W H Gerlich; F Lampert
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

2.  Autorepression of rfx1 gene expression: functional conservation from yeast to humans in response to DNA replication arrest.

Authors:  Yoav Lubelsky; Nina Reuven; Yosef Shaul
Journal:  Mol Cell Biol       Date:  2005-12       Impact factor: 4.272

3.  RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer.

Authors:  C A Siegrist; B Durand; P Emery; E David; P Hearing; B Mach; W Reith
Journal:  Mol Cell Biol       Date:  1993-10       Impact factor: 4.272
  3 in total

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