Literature DB >> 22368247

SiteComp: a server for ligand binding site analysis in protein structures.

Yingjie Lin1, Seungyeul Yoo, Roberto Sanchez.   

Abstract

MOTIVATION: Computational characterization of ligand-binding sites in proteins provides preliminary information for functional annotation, protein design and ligand optimization. SiteComp implements binding site analysis for comparison of binding sites, evaluation of residue contribution to binding sites and identification of sub-sites with distinct molecular interaction properties.
AVAILABILITY AND IMPLEMENTATION: The SiteComp server and tutorials are freely available at http://sitecomp.sanchezlab.org.

Mesh:

Substances:

Year:  2012        PMID: 22368247      PMCID: PMC3324516          DOI: 10.1093/bioinformatics/bts095

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  13 in total

1.  Computational alanine scanning of protein-protein interfaces.

Authors:  Tanja Kortemme; David E Kim; David Baker
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2.  Predicting free energy changes using structural ensembles.

Authors:  Alexander Benedix; Caroline M Becker; Bert L de Groot; Amedeo Caflisch; Rainer A Böckmann
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3.  EasyMIFS and SiteHound: a toolkit for the identification of ligand-binding sites in protein structures.

Authors:  Dario Ghersi; Roberto Sanchez
Journal:  Bioinformatics       Date:  2009-09-29       Impact factor: 6.937

4.  A computational procedure for determining energetically favorable binding sites on biologically important macromolecules.

Authors:  P J Goodford
Journal:  J Med Chem       Date:  1985-07       Impact factor: 7.446

5.  Comparison between computational alanine scanning and per-residue binding free energy decomposition for protein-protein association using MM-GBSA: application to the TCR-p-MHC complex.

Authors:  Vincent Zoete; Olivier Michielin
Journal:  Proteins       Date:  2007-06-01

Review 6.  Beyond structural genomics: computational approaches for the identification of ligand binding sites in protein structures.

Authors:  Dario Ghersi; Roberto Sanchez
Journal:  J Struct Funct Genomics       Date:  2011-05-03

7.  Kinetic computational alanine scanning: application to p53 oligomerization.

Authors:  Lillian T Chong; William C Swope; Jed W Pitera; Vijay S Pande
Journal:  J Mol Biol       Date:  2006-01-17       Impact factor: 5.469

8.  High-resolution structures of adenylate kinase from yeast ligated with inhibitor Ap5A, showing the pathway of phosphoryl transfer.

Authors:  U Abele; G E Schulz
Journal:  Protein Sci       Date:  1995-07       Impact factor: 6.725

9.  The FoldX web server: an online force field.

Authors:  Joost Schymkowitz; Jesper Borg; Francois Stricher; Robby Nys; Frederic Rousseau; Luis Serrano
Journal:  Nucleic Acids Res       Date:  2005-07-01       Impact factor: 16.971

10.  SITEHOUND-web: a server for ligand binding site identification in protein structures.

Authors:  Marylens Hernandez; Dario Ghersi; Roberto Sanchez
Journal:  Nucleic Acids Res       Date:  2009-04-26       Impact factor: 16.971

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  11 in total

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Authors:  Xiliang Zheng; Linfeng Gan; Erkang Wang; Jin Wang
Journal:  AAPS J       Date:  2012-11-22       Impact factor: 4.009

2.  Crystal Structures of the SpoIID Lytic Transglycosylases Essential for Bacterial Sporulation.

Authors:  Salvatore Nocadello; George Minasov; Ludmilla S Shuvalova; Ievgeniia Dubrovska; Elisabetta Sabini; Wayne F Anderson
Journal:  J Biol Chem       Date:  2016-05-18       Impact factor: 5.157

3.  Considerations of Protein Subpockets in Fragment-Based Drug Design.

Authors:  Matthew Bartolowits; V Jo Davisson
Journal:  Chem Biol Drug Des       Date:  2015-08-31       Impact factor: 2.817

4.  Creation of a free, Internet-accessible database: the Multiple Target Ligand Database.

Authors:  Chao Chen; Yang He; Jianhui Wu; Jinming Zhou
Journal:  J Cheminform       Date:  2015-04-15       Impact factor: 5.514

Review 5.  Computer-Aided Protein Directed Evolution: a Review of Web Servers, Databases and other Computational Tools for Protein Engineering.

Authors:  Rajni Verma; Ulrich Schwaneberg; Danilo Roccatano
Journal:  Comput Struct Biotechnol J       Date:  2012-10-22       Impact factor: 7.271

Review 6.  Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology.

Authors:  Bruno O Villoutreix; Melaine A Kuenemann; Jean-Luc Poyet; Heriberto Bruzzoni-Giovanelli; Céline Labbé; David Lagorce; Olivier Sperandio; Maria A Miteva
Journal:  Mol Inform       Date:  2014-06-02       Impact factor: 3.353

Review 7.  Proteins and Their Interacting Partners: An Introduction to Protein-Ligand Binding Site Prediction Methods.

Authors:  Daniel Barry Roche; Danielle Allison Brackenridge; Liam James McGuffin
Journal:  Int J Mol Sci       Date:  2015-12-15       Impact factor: 5.923

8.  Biological and functional relevance of CASP predictions.

Authors:  Tianyun Liu; Shirbi Ish-Shalom; Wen Torng; Aleix Lafita; Christian Bock; Matthew Mort; David N Cooper; Spencer Bliven; Guido Capitani; Sean D Mooney; Russ B Altman
Journal:  Proteins       Date:  2017-10-17

9.  AFAL: a web service for profiling amino acids surrounding ligands in proteins.

Authors:  Mauricio Arenas-Salinas; Samuel Ortega-Salazar; Fernando Gonzales-Nilo; Ehmke Pohl; David S Holmes; Raquel Quatrini
Journal:  J Comput Aided Mol Des       Date:  2014-08-02       Impact factor: 3.686

Review 10.  Exploring the computational methods for protein-ligand binding site prediction.

Authors:  Jingtian Zhao; Yang Cao; Le Zhang
Journal:  Comput Struct Biotechnol J       Date:  2020-02-17       Impact factor: 7.271

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