Literature DB >> 22364433

Chronic calcaneal osteomyelitis associated with soft-tissue defect could be successfully treated with platelet-rich plasma: a case report.

Hsin-Fu Wang1, You-Shui Gao, Ting Yuan, Xiao-Wei Yu, Chang-Qing Zhang.   

Abstract

Chronic osteomyelitis associated with soft-tissue defect following surgical management is a severe complication for orthopaedic surgeons. Traditionally, the treatment protocol for the notorious complication involved thorough debridement, bone grafting, long-term antibiotic use and flap surgery. Alternatively, platelet-rich plasma (PRP), a high concentration of platelets collected via centrifugation, has been successfully used as an adjuvant treatment for bone and soft-tissue infection in medical practices. PRP has numerous significant advantages, including stypsis, inflammation remission and reducing the amount of infected fluid. It increases bone and soft-tissue healing and allows fewer opportunities for transplant rejection. Through many years of studies showing the advantages of PRP, it has become preferred organic product for the clinical treatment of infections, especially for chronic osteomyelitis associated with soft-tissue defect. To promote the clinical use of this simple and efficacious technique in trauma, we report the case of a patient with chronic calcaneal osteomyelitis associated with soft-tissue defect that healed uneventfully with PRP.
© 2012 The Authors. International Wound Journal © 2012 Blackwell Publishing Ltd and Medicalhelplines.com Inc.

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Year:  2012        PMID: 22364433      PMCID: PMC7950503          DOI: 10.1111/j.1742-481X.2012.00951.x

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  29 in total

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2.  The role of growth factors in the healing of chronic wounds.

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Review 4.  Systemic antibiotic therapy for chronic osteomyelitis in adults.

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Review 5.  Infection and musculoskeletal conditions: Osteomyelitis.

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7.  [Experimental study on effect of platelet-rich plasma in repair of bone defect].

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  6 in total

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Review 3.  Platelet-Rich Plasma Therapy in the Treatment of Diseases Associated with Orthopedic Injuries.

Authors:  Jie Fang; Xin Wang; Wen Jiang; Yaqiong Zhu; Yongqiang Hu; Yanxu Zhao; Xueli Song; Jinjuan Zhao; Wenlong Zhang; Jiang Peng; Yu Wang
Journal:  Tissue Eng Part B Rev       Date:  2020-11-03       Impact factor: 7.376

4.  Temporal Bacteriostatic Effect and Growth Factor Loss in Equine Platelet Components and Plasma Cultured with Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus: A Comparative In Vitro Study.

Authors:  Catalina López; María E Alvarez; Jorge U Carmona
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Review 5.  An overview of platelet products (PRP, PRGF, PRF, etc.) in the Iranian studies.

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6.  Antibacterial Activity of Leukocyte- and Platelet-Rich Plasma: An In Vitro Study.

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Journal:  Biomed Res Int       Date:  2018-06-27       Impact factor: 3.411

  6 in total

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