Tomasz Szponder1,2, Joanna Wessely-Szponder3, Aleksandra Sobczyńska-Rak4,2, Beata Żylińska4,2, Radosław P Radzki5, Izabella Polkowska4,2. 1. Clinic of Animal Surgery, Faculty of Veterinary Medicine, University of Life Sciences, Lublin, Poland tomszpon@op.pl. 2. Department of Animal Surgery, Faculty of Veterinary Medicine, University of Life Sciences, Lublin, Poland. 3. Department of Pathophysiology, Faculty of Veterinary Medicine, University of Life Sciences, Lublin, Poland. 4. Clinic of Animal Surgery, Faculty of Veterinary Medicine, University of Life Sciences, Lublin, Poland. 5. Department of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences, Lublin, Poland.
Abstract
AIM: To assess the applicability of β-tri-calcium phosphate (TCP) and platelet-rich plasma (PRP) in the treatment of comminuted fractures in small animals. MATERIAL AND METHODS: The experimental study was carried out on 16 New Zealand White rabbits. After creating the bone defect and performing tibial osteotomy, TCP implants containing activated PRP were introduced into the fracture and the defect. The fracture was stabilised using external fixators or intramedullary nails. After 12 weeks, the animals were euthanised, and radiological, histological, scanning electron microscopy and peripheral quantitative computed tomography examinations were performed. The analysis also covered the results of fracture treatment in 37 small animals (cats and dogs) in which treatment with TCP containing PRP was used as an alternative to cancellous bone implantation. RESULTS: Correct bone union was observed in the experimental groups, TCP remained visible at the site of the fracture after 12 weeks. In the clinical application in small animals, bone union was observed in over 91% of treated animals. CONCLUSION: β-TCP and activated PRP may be an effective method of bone union enhancement in the treatment of comminuted fractures in small animals. Copyright
AIM: To assess the applicability of β-tri-calcium phosphate (TCP) and platelet-rich plasma (PRP) in the treatment of comminuted fractures in small animals. MATERIAL AND METHODS: The experimental study was carried out on 16 New Zealand White rabbits. After creating the bone defect and performing tibial osteotomy, TCP implants containing activated PRP were introduced into the fracture and the defect. The fracture was stabilised using external fixators or intramedullary nails. After 12 weeks, the animals were euthanised, and radiological, histological, scanning electron microscopy and peripheral quantitative computed tomography examinations were performed. The analysis also covered the results of fracture treatment in 37 small animals (cats and dogs) in which treatment with TCP containing PRP was used as an alternative to cancellous bone implantation. RESULTS: Correct bone union was observed in the experimental groups, TCP remained visible at the site of the fracture after 12 weeks. In the clinical application in small animals, bone union was observed in over 91% of treated animals. CONCLUSION: β-TCP and activated PRP may be an effective method of bone union enhancement in the treatment of comminuted fractures in small animals. Copyright
Authors: Adelina S Plachokova; Juliette van den Dolder; Paul J Stoelinga; John A Jansen Journal: Clin Oral Implants Res Date: 2006-06 Impact factor: 5.977
Authors: H G Schmoekel; F E Weber; K Hurter; J C Schense; G Seiler; U Ryrz; D Spreng; P Schawalder; J Hubbell Journal: J Small Anim Pract Date: 2005-01 Impact factor: 1.522
Authors: G Hauschild; H A Merten; A Bader; G Uhr; A Deivick; A MeyeLindenberg; M Fehr Journal: Vet Comp Orthop Traumatol Date: 2005 Impact factor: 1.358
Authors: Zvi Artzi; Miron Weinreb; Navot Givol; Michael D Rohrer; Carlos E Nemcovsky; Hari S Prasad; Haim Tal Journal: Int J Oral Maxillofac Implants Date: 2004 May-Jun Impact factor: 2.804
Authors: Ihsan Caglar Cinar; Bahattin Alper Gultekin; Alper Saglanmak; Serdar Yalcin; Vakur Olgac; Eitan Mijiritsky Journal: Int J Environ Res Public Health Date: 2020-03-15 Impact factor: 3.390