Literature DB >> 20176168

Ankle and foot osteomyelitis: treatment protocol and clinical results.

Konstantinos N Malizos1, Nikolaos E Gougoulias, Zoe H Dailiana, Sokratis Varitimidis, Konstantinos A Bargiotas, Dionysios Paridis.   

Abstract

INTRODUCTION: A management protocol for ankle and foot osteomyelitis and the outcome in 84 patients treated in a unit with special interest in musculoskeletal infection, is presented. PATIENTS AND METHODS: Patients' mean age was 50.7+/-16.5 years and mean follow-up 31.5+/-18.2 months. Systemic antibiotics were administered initially empirically, and later according to cultures. Surgical treatment included surgical debridement and bead-pouch technique, minor amputation (ray or toe), below knee amputation, and joint fusion. "Second-look" procedures were performed after 48-7h. Vascularised grafts or Ilizarov's technique were used for bone defect reconstruction. Soft tissues were managed according the 'reconstructive ladder' concept.
RESULTS: Host-type (Cierny's classification) was A in 25, B in 53 and C in 6 patients. Seventy-six infections were chronic. Causes were: open trauma without fracture (45/84), open fractures (9/84), ORIF of closed fractures (25/84) and elective surgery (5/84). Patients underwent 3.0+/-1.5 (range 1-10) operative procedures and spent 14.8+/-12.2 (range 3-60) days in hospital. Two (host-C) patients died. Complications requiring reoperations occurred in 20/84 (2/25 host-A, 16/53 host-B, 2/6 host-C; significant difference between host-A versus host-B and -C patients, p<0.001). Infection recurrence occurred in 12 (none host-A; significant difference between host-A versus host-B and -C patients, p<0.001). Multiple organisms were isolated in 39/84. Ankle arthrodesis using external fixation was performed in 9 (fusion rate 8/9). The free vascularised fibula graft was used in 2 and distraction osteogenesis in 8 patients with a mean bone defect of 5.4 cm (range 3-13). Below knee amputations were performed in 5/84 (3/53 host-B, 2/6 host-C) and foot ray amputations in 8/84 (6/53 host-B, 2/6 host-C). Soft tissue coverage required: free muscle flap transfer in 6/84, reverse soleus flap in 1/84, local fasciocutaneous flaps in 7/84, split thickness skin grafts in 5/84, and vacuum assisted closure in 5/84 patients. Eighty-two surviving patients, including amputees, were able to mobilise independently and were satisfied with the result of treatment.
CONCLUSIONS: Host-B and -C patients had more complications and infection recurrences and occasionally required amputations. Reconstructive procedures were performed for limb salvage in patients with soft tissue and bone defects and restoration of a functional limb was achieved. Copyright 2009 Elsevier Ltd. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20176168     DOI: 10.1016/j.injury.2009.09.010

Source DB:  PubMed          Journal:  Injury        ISSN: 0020-1383            Impact factor:   2.586


  4 in total

1.  Silver nanoparticle deposited implants to treat osteomyelitis.

Authors:  Samit Kumar Nandi; Anish Shivaram; Susmita Bose; Amit Bandyopadhyay
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2017-05-15       Impact factor: 3.368

2.  Chronic calcaneal osteomyelitis associated with soft-tissue defect could be successfully treated with platelet-rich plasma: a case report.

Authors:  Hsin-Fu Wang; You-Shui Gao; Ting Yuan; Xiao-Wei Yu; Chang-Qing Zhang
Journal:  Int Wound J       Date:  2012-02-24       Impact factor: 3.315

3.  Predisposing factors for recurrence of chronic posttraumatic osteomyelitis: a retrospective observational cohort study from a tertiary referral center in Brazil.

Authors:  Luciana Souza Jorge; Alceu G Chueire; Patricia Silva Fucuta; Mauricio N Machado; Maria Gabriele L Oliveira; Marcelo A Nakazone; Mauro José Salles
Journal:  Patient Saf Surg       Date:  2017-06-02

4.  Insights into treatment and outcome of fracture-related infection: a systematic literature review.

Authors:  H Bezstarosti; E M M Van Lieshout; L W Voskamp; K Kortram; W Obremskey; M A McNally; W J Metsemakers; M H J Verhofstad
Journal:  Arch Orthop Trauma Surg       Date:  2018-10-20       Impact factor: 3.067

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.