Literature DB >> 2236289

Antimalarial activity of Tanzanian medicinal plants.

H Weenen1, M H Nkunya, D H Bray, L B Mwasumbi, L S Kinabo, V A Kilimali.   

Abstract

Tanzanian medicinal plants were extracted and tested for in vitro antimalarial activity, using the multidrug resistant K1 strain of Plasmodium falciparum. Of 49 plants investigated, extracts of three plants were found to have an IC50 between 5-10 micrograms/ml, extracts of 18 other plants showed an IC50 between 10 and 50 micrograms/ml, all others were less active. The three most active extracts were obtained from the tubers of Cyperus rotundus L. (Cyperaceae), the rootbark of Hoslundia opposita Vahl. (Labiatae), and the rootbark of Lantana camara L. (Verbenaceae).

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Year:  1990        PMID: 2236289     DOI: 10.1055/s-2006-960984

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  17 in total

1.  Folk medicinal uses of Verbenaceae family plants in Bangladesh.

Authors:  Mohammed Rahmatullah; Rownak Jahan; F M Safiul Azam; S Hossan; M A H Mollik; Taufiq Rahman
Journal:  Afr J Tradit Complement Altern Med       Date:  2011-07-03

2.  The antiplasmodial agents of the stem bark of Entandrophragma angolense (Meliaceae).

Authors:  Jean Bickii; Guy Raymond Feuya Tchouya; Jean Claude Tchouankeu; Etienne Tsamo
Journal:  Afr J Tradit Complement Altern Med       Date:  2006-11-13

3.  Antimalarial activity in crude extracts of some Cameroonian medicinal plants.

Authors:  Jean Bickii; Guy Raymond Feuya Tchouya; Jean Claude Tchouankeu; Etienne Tsamo
Journal:  Afr J Tradit Complement Altern Med       Date:  2006-08-28

4.  In vitro antimalarial activity of traditionally used Western Ghats plants from India and their interactions with chloroquine against chloroquine-resistant Plasmodium falciparum.

Authors:  Kuppusamy Chenniappan; Murugan Kadarkarai
Journal:  Parasitol Res       Date:  2010-08-03       Impact factor: 2.289

5.  Potent antimalarial activity of the alkaloid nitidine, isolated from a Kenyan herbal remedy.

Authors:  D M Gakunju; E K Mberu; S F Dossaji; A I Gray; R D Waigh; P G Waterman; W M Watkins
Journal:  Antimicrob Agents Chemother       Date:  1995-12       Impact factor: 5.191

6.  Screening of traditionally used plants for in vivo antimalarial activity in mice.

Authors:  Esther Innocent; Mainen J Moshi; Pax J Masimba; Zakaria H Mbwambo; Modest C Kapingu; Appolinary Kamuhabwa
Journal:  Afr J Tradit Complement Altern Med       Date:  2009-03-07

Review 7.  Plants in traditional medicine with special reference to Cyperus rotundus L.: a review.

Authors:  Arunagiri Kamala; Sushil Kumar Middha; Chandrakant S Karigar
Journal:  3 Biotech       Date:  2018-07-09       Impact factor: 2.406

8.  In vitro reduction of Plasmodium falciparum gametocytes: Artemisia spp. tea infusions vs. artemisinin.

Authors:  Danielle Snider; Pamela J Weathers
Journal:  J Ethnopharmacol       Date:  2020-11-30       Impact factor: 4.360

9.  Cameroonian medicinal plants: pharmacology and derived natural products.

Authors:  Victor Kuete; Thomas Efferth
Journal:  Front Pharmacol       Date:  2010-10-25       Impact factor: 5.810

10.  Antinociceptive Effect of Cyperi rhizoma and Corydalis tuber Extracts on Neuropathic Pain in Rats.

Authors:  Jae-Gyun Choi; Suk-Yun Kang; Jae-Min Kim; Dae-Hyun Roh; Seo-Yeon Yoon; Jin Bong Park; Jang-Hern Lee; Hyun-Woo Kim
Journal:  Korean J Physiol Pharmacol       Date:  2012-12-10       Impact factor: 2.016

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