Literature DB >> 22358676

Use of established hepatoma cell lines in biotoxicology.

M Ferro1, A M Bassi, S Penco, G Nanni.   

Abstract

CONCLUSIONS: In conclusion, hepatoma cell lines displaying multiple combinations of bioactivating and inactivating enzymes, even if do not seem to represent liver-specific bio-indicators of toxicity, are a polyvalent liver system, suitable to evaluate particular end-points.

Entities:  

Year:  1993        PMID： 22358676     DOI： 10.1007/BF00746076

Source DB:  PubMed          Journal:  Cytotechnology        ISSN： 0920-9069            Impact factor:   2.058


  14 in total

1.  Drug metabolism by the human hepatoma cell, Hep G2.

Authors:  S Sassa; O Sugita; R A Galbraith; A Kappas
Journal:  Biochem Biophys Res Commun       Date:  1987-02-27       Impact factor: 3.575

2.  Presence of cytochrome P-450- and cytochrome P-448-dependent monooxygenase functions in hepatoma cell lines.

Authors:  F J Wiebel; T Wolff; M Lambiotte
Journal:  Biochem Biophys Res Commun       Date:  1980-05-30       Impact factor: 3.575

3.  Metabolic activation of benzo[a]pyrene by a human hepatoma cell line.

Authors:  L Diamond; F Kruszewski; D P Aden; B B Knowles; W M Baird
Journal:  Carcinogenesis       Date:  1980       Impact factor: 4.944

4.  Characterization of the Ah receptor mediating aryl hydrocarbon hydroxylase induction in the human liver cell line Hep G2.

Authors:  E A Roberts; K C Johnson; P A Harper; A B Okey
Journal:  Arch Biochem Biophys       Date:  1990-02-01       Impact factor: 4.013

5.  Induction of cytochrome P450IA1 in mouse hepatoma cells by several chemicals. Phenobarbital and TCDD induce the same form of cytochrome P450.

Authors:  S O Kärenlampi; K Tuomi; M Korkalainen; H Raunio
Journal:  Biochem Pharmacol       Date:  1989-05-01       Impact factor: 5.858

6.  Metabolism of benzo(a)pyrene by variant mouse hepatoma cells.

Authors:  E L Schaefer; J K Selkirk
Journal:  Cancer Res       Date:  1985-08       Impact factor: 12.701

7.  Interleukin-6 down regulates the expression of transcripts encoding cytochrome P450 IA1, IA2 and IIIA3 in human hepatoma cells.

Authors:  Y Fukuda; N Ishida; T Noguchi; A Kappas; S Sassa
Journal:  Biochem Biophys Res Commun       Date:  1992-04-30       Impact factor: 3.575

8.  Evaluation of a human hepatoma cell line as a target cell in genetic toxicology.

Authors:  K L Dearfield; D Jacobson-Kram; N A Brown; J R Williams
Journal:  Mutat Res       Date:  1983-03       Impact factor: 2.433

9.  Induction of drug metabolizing enzymes in human liver cell line Hep G2.

Authors:  J R Dawson; D J Adams; C R Wolf
Journal:  FEBS Lett       Date:  1985-04-22       Impact factor: 4.124

10.  Biochemical properties of carcinogen-metabolizing enzymes in cultured hepatoma cells.

Authors:  M Ferro; U M Marinari; A M Bassi; G Nanni
Journal:  Toxicol Pathol       Date:  1987       Impact factor: 1.902
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