Literature DB >> 22336130

Redefining the golden hour for severe head injury in an urban setting: the effect of prehospital arrival times on patient outcomes.

Michael M Dinh1, Kendall Bein, Susan Roncal, Christopher M Byrne, Jeffrey Petchell, Jeffrey Brennan.   

Abstract

BACKGROUND: In patients with severe head injuries, transportation to a trauma centre within the "golden hour" are important markers of trauma system effectiveness but evidence regarding impacts on patient outcomes is limited.
OBJECTIVE: To determine the effect of patient arrival within the golden hour on patient outcomes.
METHODS: A retrospective cohort of adult patients with severe head injuries (head AIS ≥ 3) arriving within 24h of injury was identified using the trauma registry from 2000 to 2011. Survival analysis was used to determine the effect of patient arrival time on overall mortality. Study outcomes were in hospital mortality and survival to hospital discharge without requiring transfer for ongoing rehabilitation or nursing home care.
RESULTS: There was a significant association with mortality with each incremental minute of patient arrival (HR 1.002, 95%CI 1.001-1.004, p=0.001). There was however no survival benefit observed for patients arriving within 60 min of injury time (HR 0.77, 95%CI 0.50-1.18, p=0.22) but an apparent benefit for those presenting within 2h of injury time (HR 0.31, 95%CI 0.15-0.66, p=0.002). Patient arrival within 60 min of injury time was associated with increased odds of survival to hospital discharge without requiring ongoing rehabilitation (OR 1.78, 95%CI 1.14-2.79, p=0.01).
CONCLUSION: A survival benefit exists in patients arriving earlier to hospital after severe head injury but the benefit may extend beyond the golden hour. There was evidence of improved functional outcomes in patients arriving within 60 min of injury time. Crown
Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 22336130     DOI: 10.1016/j.injury.2012.01.011

Source DB:  PubMed          Journal:  Injury        ISSN: 0020-1383            Impact factor:   2.586


  28 in total

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9.  Association of transport time with adverse outcome in paediatric trauma.

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10.  Real-Time Detection and Monitoring of Acute Brain Injury Utilizing Evoked Electroencephalographic Potentials.

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