Literature DB >> 22332096

Omega-3 fatty acids EPA and DHA: health benefits throughout life.

Danielle Swanson1, Robert Block, Shaker A Mousa.   

Abstract

Omega-3 [(n-3)] fatty acids have been linked to healthy aging throughout life. Recently, fish-derived omega-3 fatty acids EPA and DHA have been associated with fetal development, cardiovascular function, and Alzheimer's disease. However, because our bodies do not efficiently produce some omega-3 fatty acids from marine sources, it is necessary to obtain adequate amounts through fish and fish-oil products. Studies have shown that EPA and DHA are important for proper fetal development, including neuronal, retinal, and immune function. EPA and DHA may affect many aspects of cardiovascular function including inflammation, peripheral artery disease, major coronary events, and anticoagulation. EPA and DHA have been linked to promising results in prevention, weight management, and cognitive function in those with very mild Alzheimer's disease.

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Year:  2012        PMID: 22332096      PMCID: PMC3262608          DOI: 10.3945/an.111.000893

Source DB:  PubMed          Journal:  Adv Nutr        ISSN: 2161-8313            Impact factor:   8.701


  55 in total

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Journal:  Circulation       Date:  2002-11-19       Impact factor: 29.690

2.  Omega-3 fatty acids and decidual cell prostaglandin production in response to the inflammatory cytokine IL-1beta.

Authors:  Ashley S Roman; Jeremy Schreher; Andrew P Mackenzie; Peter W Nathanielsz
Journal:  Am J Obstet Gynecol       Date:  2006-06-21       Impact factor: 8.661

3.  Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment.

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Journal:  Lipids       Date:  2000-12       Impact factor: 1.880

4.  Compartmental modeling to quantify alpha-linolenic acid conversion after longer term intake of multiple tracer boluses.

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5.  Algal docosahexaenoic acid affects plasma lipoprotein particle size distribution in overweight and obese adults.

Authors:  Lisa M Neff; Jill Culiner; Susanna Cunningham-Rundles; Cynthia Seidman; Diane Meehan; Janet Maturi; Knut M Wittkowski; Barbara Levine; Jan L Breslow
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6.  Omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trial.

Authors:  Yvonne Freund-Levi; Maria Eriksdotter-Jönhagen; Tommy Cederholm; Hans Basun; Gerd Faxén-Irving; Anita Garlind; Inger Vedin; Bengt Vessby; Lars-Olof Wahlund; Jan Palmblad
Journal:  Arch Neurol       Date:  2006-10

7.  A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.

Authors:  Giselle P Lim; Frédéric Calon; Takashi Morihara; Fusheng Yang; Bruce Teter; Oliver Ubeda; Norman Salem; Sally A Frautschy; Greg M Cole
Journal:  J Neurosci       Date:  2005-03-23       Impact factor: 6.167

8.  Long-chain conversion of [13C]linoleic acid and alpha-linolenic acid in response to marked changes in their dietary intake in men.

Authors:  Nahed Hussein; Eric Ah-Sing; Paul Wilkinson; Clare Leach; Bruce A Griffin; D Joe Millward
Journal:  J Lipid Res       Date:  2004-12-01       Impact factor: 5.922

9.  Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis.

Authors:  Mitsuhiro Yokoyama; Hideki Origasa; Masunori Matsuzaki; Yuji Matsuzawa; Yasushi Saito; Yuichi Ishikawa; Shinichi Oikawa; Jun Sasaki; Hitoshi Hishida; Hiroshige Itakura; Toru Kita; Akira Kitabatake; Noriaki Nakaya; Toshiie Sakata; Kazuyuki Shimada; Kunio Shirato
Journal:  Lancet       Date:  2007-03-31       Impact factor: 79.321

10.  Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study.

Authors:  A M Tully; H M Roche; R Doyle; C Fallon; I Bruce; B Lawlor; D Coakley; M J Gibney
Journal:  Br J Nutr       Date:  2003-04       Impact factor: 3.718

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  215 in total

1.  Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics: 2019 Lewis K. Dahl Memorial Lecture.

Authors:  John D Imig; Wojciech K Jankiewicz; Abdul H Khan
Journal:  Hypertension       Date:  2020-06-01       Impact factor: 10.190

2.  Evaluation of Contamination Status and Health Risk Assessment of Essential and Toxic Metals in Cyprinus carpio from Mangla Lake, Pakistan.

Authors:  Muhammad Saleem; Zongbo Shi; Munir H Shah
Journal:  Biol Trace Elem Res       Date:  2021-01-07       Impact factor: 3.738

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Review 4.  Impact of nutrition on pollutant toxicity: an update with new insights into epigenetic regulation.

Authors:  Jessie B Hoffman; Michael C Petriello; Bernhard Hennig
Journal:  Rev Environ Health       Date:  2017-03-01       Impact factor: 3.458

5.  Transcriptomic and microRNA analyses of gene networks regulated by eicosapentaenoic acid in brown adipose tissue of diet-induced obese mice.

Authors:  Mandana Pahlavani; Nadeeja N Wijayatunga; Nishan S Kalupahana; Latha Ramalingam; Preethi H Gunaratne; Cristian Coarfa; Kimal Rajapakshe; Pratibha Kottapalli; Naima Moustaid-Moussa
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2018-09-25       Impact factor: 4.698

Review 6.  Regulation of platelet function and thrombosis by omega-3 and omega-6 polyunsaturated fatty acids.

Authors:  Reheman Adili; Megan Hawley; Michael Holinstat
Journal:  Prostaglandins Other Lipid Mediat       Date:  2018-09-25       Impact factor: 3.072

7.  Maternal n-3 PUFA supplementation promotes fetal brown adipose tissue development through epigenetic modifications in C57BL/6 mice.

Authors:  Rong Fan; Ashley Mulcahy Toney; Yura Jang; Seung-Hyun Ro; Soonkyu Chung
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2018-09-25       Impact factor: 4.698

8.  Amyloid beta (Aβ) peptide modulators and other current treatment strategies for Alzheimer's disease (AD).

Authors:  Walter J Lukiw
Journal:  Expert Opin Emerg Drugs       Date:  2012-03-23       Impact factor: 4.191

9.  Lack of ∆5 Desaturase Activity Impairs EPA and DHA Synthesis in Fish Cells from Red Sea Bream and Japanese Flounder.

Authors:  Hayato Nyunoya; Tatsuki Noda; You Kawamoto; Yasuhiro Hayashi; Yohei Ishibashi; Makoto Ito; Nozomu Okino
Journal:  Mar Biotechnol (NY)       Date:  2021-06-26       Impact factor: 3.619

10.  Mechanism of the modulation of BK potassium channel complexes with different auxiliary subunit compositions by the omega-3 fatty acid DHA.

Authors:  Toshinori Hoshi; Yutao Tian; Rong Xu; Stefan H Heinemann; Shangwei Hou
Journal:  Proc Natl Acad Sci U S A       Date:  2013-03-04       Impact factor: 11.205

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