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Literature DB >> 22327631

Sorting cells by size, shape and deformability.

Jason P Beech¹, Stefan H Holm, Karl Adolfsson, Jonas O Tegenfeldt.

Abstract

While size has been widely used as a parameter in cellular separations, in this communication we show how shape and deformability, a mainly untapped source of specificity in preparative and analytical microfluidic devices can be measured and used to separate cells.

Mesh：

Year: 2012 PMID： 22327631 DOI： 10.1039/c2lc21083e

Source DB: PubMed Journal: Lab Chip ISSN： 1473-0189 Impact factor: 6.799

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Cited

62 in total

Review 1. Rare cell isolation and analysis in microfluidics.

Authors: Yuchao Chen; Peng Li; Po-Hsun Huang; Yuliang Xie; John D Mai; Lin Wang; Nam-Trung Nguyen; Tony Jun Huang
Journal: Lab Chip Date: 2014-02-21 Impact factor: 6.799

2. Motion of an elastic capsule in a constricted microchannel.

Authors: Cecilia Rorai; Antoine Touchard; Lailai Zhu; Luca Brandt
Journal: Eur Phys J E Soft Matter Date: 2015-05-26 Impact factor: 1.890

3. Deformability-based red blood cell separation in deterministic lateral displacement devices-A simulation study.

Authors: Timm Krüger; David Holmes; Peter V Coveney
Journal: Biomicrofluidics Date: 2014-10-13 Impact factor: 2.800

4. Real-time deformability cytometry: on-the-fly cell mechanical phenotyping.

Authors: Oliver Otto; Philipp Rosendahl; Alexander Mietke; Stefan Golfier; Christoph Herold; Daniel Klaue; Salvatore Girardo; Stefano Pagliara; Andrew Ekpenyong; Angela Jacobi; Manja Wobus; Nicole Töpfner; Ulrich F Keyser; Jörg Mansfeld; Elisabeth Fischer-Friedrich; Jochen Guck
Journal: Nat Methods Date: 2015-02-02 Impact factor: 28.547

5. Simultaneous measurement of erythrocyte deformability and blood viscoelasticity using micropillars and co-flowing streams under pulsatile blood flows.

Authors: Yang Jun Kang
Journal: Biomicrofluidics Date: 2017-01-06 Impact factor: 2.800

Sorting cells by size, shape and deformability.

Review 1. Rare cell isolation and analysis in microfluidics.

2. Motion of an elastic capsule in a constricted microchannel.

3. Deformability-based red blood cell separation in deterministic lateral displacement devices-A simulation study.

4. Real-time deformability cytometry: on-the-fly cell mechanical phenotyping.

5. Simultaneous measurement of erythrocyte deformability and blood viscoelasticity using micropillars and co-flowing streams under pulsatile blood flows.

6. On-chip density-based purification of liposomes.

Review 7. Shape-based separation of micro-/nanoparticles in liquid phases.

8. Rotational separation of non-spherical bioparticles using I-shaped pillar arrays in a microfluidic device.

9. Microfluidic electrical sorting of particles based on shape in a spiral microchannel.

10. Microfluidic Platform for the Isolation of Cancer-Cell Subpopulations Based on Single-Cell Glycolysis.